Patents by Inventor Toshio Satoh
Toshio Satoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5006548Abstract: Compounds of the general formula: ##STR1## wherein R.sup.1 is heterocyclic group other than pyridyl and which is unsubstituted or substituted with lower alkyl or lower alkoxycarbonyl, R.sup.2 is hydrogen, halogen, or nitro, and R.sup.3 is carboxy group or its functional derivative, with the proviso that when R.sup.1 is an unsubstituted furyl, or furyl mono- or polysubstituted with alkyl and R.sup.2 is hydrogen, then R.sup.3 is functional derivative of carboxy and, where applicable, pharmaceutically acceptable salts thereof are hyaluronidase inhibitors and useful as anti-allergic agent.Type: GrantFiled: August 7, 1989Date of Patent: April 9, 1991Assignee: Sawai Pharmaceutical Co., Ltd.Inventors: Toshio Satoh, Hitoshi Matsumoto, Hisao Kakegawa, Yoshiko Kato, Juichi Riku, Junji Yoshinaga, Yoshifumi Kanamoto
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Patent number: 5004742Abstract: The present invention relates to novel benzothiazine-1,1-dioxide derivatives. These benzothiazine-1,1-dioxide derivatives have a high hyaluronidase-inhibiting activity and accordingly can be used in drugs such as anti-inflammatory agent, anti-allergic agent and the like.Type: GrantFiled: August 14, 1989Date of Patent: April 2, 1991Assignee: Nippon Hypox Laboratories IncorporatedInventors: Toshio Satoh, Yasunori Niiro, Hisao Kakegawa, Hitoshi Matsumoto
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Patent number: 4822791Abstract: This invention relates to pharmaceutical compositions of compounds of the general formula: ##STR1## wherein R.sup.1 is an aryl group or a substituted aryl group wherein the substituent is halogen, hydroxy, C.sub.(1-6) lower alkoxy, C.sub.(1-6) lower alkylenedioxy, halo C.sub.(1-6) lower alkyl, cyano, nitro, mono- or di-C.sub.(1-6) alkylamino or C.sub.(1-6) lower alkanoylamino; or a 5-membered or 6-membered C.sub.(1-6) alkyl substituted or unsubstituted heterocyclic group containing a heteroatom selected from oxygen, nitrogen, and sulfur, or a condensed heterocyclic group consisting of a heterocycle as defined above and a benzene nucleus, and R.sup.2 and R.sup.2' are, independently, hydrogen, halogen, nitro, C.sub.(1-6) lower alkyl or C.sub.(1-6) lower alkoxy. These compounds have been found to exhibit hyaluronidase inhibiting activity, anti-allergic activity and anti-ulcerous activity.Type: GrantFiled: March 2, 1988Date of Patent: April 18, 1989Assignee: Sawai Pharmaceutical Co., Ltd.Inventors: Toshio Satoh, Hitoshi Matsumoto, Hisao Kakegawa, Yoshiko Kato, Juichi Riku, Junji Yoshinaga, Yoshifumi Kanamoto
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Patent number: 4755506Abstract: Compounds of the general formula: ##STR1## wherein A and B are both hydrogen, or one of A and B is a group (G) of the formula: ##STR2## and the other is a group R.sup.5 wherein R.sup.1 is an aryl group or a heterocyclic group, both of them being optionally substituted, and R.sup.4 and R.sup.5 are both hydrogen or together form a single chemical bond,R.sup.2 and R.sup.2 ' are independently hydrogen, halogen, nitro, lower alkyl or lower alkoxy, andR.sup.3 and R.sup.3 ' are independently carboxy or its functional derivative, with the proviso that (a) when A and B are both hydrogen, then R.sup.2 and R.sup.2 ' cannot be both hydrogen,and, where applicable, pharmaceuticably acceptable salts thereof are hyaluronidase inhibitors, and useful as anti-allergic agent and anti-ulcerous agent. Among the compound (I'), those wherein when one of A and B is the group (G) and the other is the group R.sup.5 wherein R.sup.4 and R.sup.5 together form a single chemical bond, R.sup.1 is unsubstituted aryl and R.sup.2 and R.sup.Type: GrantFiled: September 19, 1986Date of Patent: July 5, 1988Assignee: Sawai Pharmaceutical Co., Ltd.Inventors: Toshio Satoh, Hitoshi Matsumoto, Hisao Kakegawa, Yoshiko Kato, Juichi Riku, Junji Yoshinaga, Yoshifumi Kanamoto
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Patent number: 4732916Abstract: A guanidinomethylbenzoic acid derivative represented by the formula ##STR1## or a salt thereof. An antiulcer agent comprising the compounds of the afore-said formula as an effective ingredient is also disclosed.Type: GrantFiled: July 16, 1986Date of Patent: March 22, 1988Assignees: Kabushiki Kaisha Med-Creat, Toshio SatohInventors: Toshio Satoh, Hitoshi Matsumoto, Hisao Kakegawa
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Patent number: 4700336Abstract: In an optical recording and playback disc apparatus, two light beams (l, m) are focused by a common focusing lens (108) onto an information track (51) of the optical recording disc, and the focused light means (l, m) form two light spots (L, M), the position thereof being controlled by a first tracking servo loop (115, 116 and 117), and furthermore, one (M) of the light spots is independently controlled from the other light spot (L) by a second tracking servo loop (120, 121 and 122).Type: GrantFiled: June 17, 1985Date of Patent: October 13, 1987Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Tomio Yoshida, Yoshinobu Nakata, Shunji Ohara, Toshio Satoh
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Patent number: 4686206Abstract: A pharmaceutical or veterinary composition for activating the function of phygocytes comprising as an effective ingredient a certain tocopheryl glycoside. The composition is useful for treating infectious diseases and malignant tumor.Type: GrantFiled: November 22, 1985Date of Patent: August 11, 1987Assignee: Sunstar Kabushiki KaishaInventors: Yasuhiro Katsuragi, Naoki Matsuda, Yoshiko Saiga, Yasunobu Kobayashi, Masakazu Nakamura, Toshio Satoh
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Patent number: 4681895Abstract: Novel N-phenyl-trans-4-guanidinomethylcyclohexanecarboxamide compounds of the formula: ##STR1## wherein R is hydrogen atom or a lower alkyl group, or a pharmaceutically acceptable salt thereof, which have excellent anti-ulcer activities and hence are useful as an anti-ulcer drug, and a pharmaceutical composition useful for the treatment and prophylaxis of peptic ulcers which comprises as an active ingredient the compound as set forth above in admixture with a conventional pharmaceutically acceptable carrier or diluent.Type: GrantFiled: March 6, 1986Date of Patent: July 21, 1987Assignee: Kanebo, Ltd.Inventors: Toshio Satoh, Goro Tsukamoto
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Patent number: 4634777Abstract: Compounds of the general formula: ##STR1## wherein A and B are both hydrogen, or one of A and B is a group (G) of the formula: ##STR2## and the other is a group R.sup.5 wherein R.sup.1 is an aryl group or a heterocyclic group, both of them being optionally substituted, and R.sup.4 and R.sup.5 are both hydrogen or together form a single chemical bond,R.sup.2 and R.sup.2 ' are independently hydrogen, halogen, nitro, lower alkyl or lower alkoxy, andR.sup.3 and R.sup.3 ' are independently carboxy or its functional derivative, with the proviso that (a) when A and B are both hydrogen, then R.sup.2 and R.sup.2 ' cannot be both hydrogen,and, where applicable, pharmaceuticably acceptable salts thereof are hyaluronidase inhibitors, and useful as anti-allergic agent and anti-ulcerous agent. Among the compound (I'), those wherein when one of A and B is the group (G) and the other is the group R.sup.5 wherein R.sup.4 and R.sup.5 together form a single chemical bond, R.sup.1 is unsubstituted aryl and R.sup.2 and R.sup.Type: GrantFiled: February 1, 1985Date of Patent: January 6, 1987Assignee: Sawai Pharmaceutical Co., Ltd.Inventors: Toshio Satoh, Hitoshi Matsumoto, Hisao Kakegawa, Yoshiko Kato, Juichi Riku, Junji Yoshinaga, Yoshifumi Kanamoto
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Patent number: 4617292Abstract: A pharmaceutical composition for producing antiallergic activity containing as an active ingredient a certain tocopherol derivative having a sugar residue at 6-position of the 3,4-dihydrobenzopyrane ring thereof. A method for producing antiallergic activity using such a tocopherol derivative and some novel tocopherol derivatives are also disclosed.Type: GrantFiled: July 17, 1985Date of Patent: October 14, 1986Assignee: Sunstar Kabushiki KaishaInventors: Toshio Satoh, Hideki Miyataka, Yukimitsu Masamoto, Takashi Asai, Kenji Hasegawa, Hisao Kakegawa
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Patent number: 4465851Abstract: A compound having the formula ##STR1## wherein R.sub.1 represents an indanyl, indolyl, quinolyl or chromonyl group, the group of the formula ##STR2## (in which R.sub.2 represents a halogen atom or a nitro group), or the group of the formula ##STR3## (in which R.sub.3 represents a halogen atom, or an alkyl, nitro, cyano, acetamino, aminosulfonyl, benzoyl, phenoxy or trifluoromethyl group, R.sub.4 represents a hydrogen or halogen atom, or an alkyl group, and R.sub.5 represents a hydrogen or halogen atom, or an alkyl group), or a pharmaceutically acceptable salt thereof. The compound is obtained by reacting 4-guanidinomethylcyclohexanecarboxylic acid or a reactive derivative thereof with a compound of the formula R.sub.1 --OH wherein R.sub.1 is the same as defined above, or a reactive derivative thereof.Type: GrantFiled: January 4, 1982Date of Patent: August 14, 1984Assignee: Nippon Chemiphar Co., Ltd.Inventors: Mutsumi Muramatsu, Toshio Satoh, Hiroyasu Sekine, Atsushi Tendo
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Patent number: 4433152Abstract: A compound of the formula, ##STR1## wherein R represents a hydrogen atom, a naphthyl, indanyl, tetrahydronaphthyl or pyridyl group, or a phenyl group which may have 1 to 3 substituents selected from the group consisting of a halogen atom, and an alkyl, alkenyl, alkoxy, alkanoyl, cyano, formyl, trifluoromethyl, phenyl, phenylalkyl, alkanoyl-amino, aminosulfonyl, carboxyl, alkoxycarbonyl, benzyloxycarbonyl, benzoylvinyl, phenylvinylcarbonyl, carboxyvinyl, and diphenyl-methyloxycarobnylvinyl group, A represents an oxygen or sulfur atom, and n represents an integer of 0 to 3, with the proviso that when n is an integer of 0, R must not be a hydrogen atom, or a pharmaceutically acceptable salt thereof is effectively useful for inhibiting a complement reaction, inflammation caused by an allergic reaction, and platelet aggregation.Type: GrantFiled: May 19, 1982Date of Patent: February 21, 1984Assignee: Nippon Chemiphar Co., Ltd.Inventors: Mutsumi Muramatsu, Toshio Satoh, Hiroyasu Sekine, Atsushi Tendo, Yoshio Kikawa, Kaname Kondo
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Patent number: 4358770Abstract: An multi-frequency antenna feed system has a corrugated conical horn and a diplexer interconnected serially to be operative in two frequency bands represented by frequencies f.sub.H and f.sub.L corresponding to wavelengths .lambda..sub.H and .lambda..sub.L respectively, where 2f.sub.L .ltoreq.f.sub.H. Corrugated grooves on the inner surface of the conical horn have the depth h, where .lambda..sub.L /4<h<.lambda..sub.L /2. The corrugated conical horn has the inside diameter at its reduced diameter end which is not less than 2.6.lambda..sub.o, where .lambda..sub.o designates a wavelength at which the depth of the corrugated grooves ranges from three quarters of the wavelength and one complete wavelength.Type: GrantFiled: September 11, 1980Date of Patent: November 9, 1982Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Toshio Satoh, Motoo Mizusawa, Fumio Takeda
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Patent number: 4348410Abstract: A compound of the formula: ##STR1## wherein R.sub.1 represents a vanilyl, napthyl, pyridyl or .alpha.-tocopheryl group, or a group of the formula, ##STR2## wherein R.sub.2 represents a hydrogen atom, a lower alkoxy, formyl, lower alkanoyl or phenyl group, or a group of the formula --(CH.sub.2).sub.n COOR.sub.3, wherein R.sub.3 represents a hydrogen atom, a lower alkyl, phenyl, benzyl, anisyl or lower alkoxycarbonylmethyl group, and n represents an integer of 0 to 2, or a pharmaceutically acceptable salt thereof is effective for use as an anti-ulcer agent.Type: GrantFiled: September 15, 1980Date of Patent: September 7, 1982Assignees: Nippon Chemiphar Co., Ltd., Teikoku Chemical Industry Co., Ltd.Inventors: Mutsumi Muramatsu, Toshio Satoh, Yukio Yanagimoto, Tadami Shinuchi, Toshio Nakajima, Isao Nakajima
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Patent number: 4215862Abstract: Disclosed is a water-surface target towed by a mother ship which comprises a towed member running underwater with a ballast weight suspended therefrom, a target pole set up on the top of the towed member, and a stabilizing plate attached to a position above the waterline of the target pole at an angle of incidence. The water-surface target can be used even under bad conditions and towed at a high speed, e.g. 30 knots, due to the towed member being capable of continually maintaining stability underwater.Type: GrantFiled: June 21, 1978Date of Patent: August 5, 1980Assignee: Japan Aircraft Mfg. Co., Ltd.Inventors: Takashi Yoshikawa, Shigeru Kato, Akira Obata, Hiroshi Shibazaki, Shigeaki Ishikawa, Toshio Satoh
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Patent number: 4216357Abstract: This invention relates to a system for optically playing back recorded signals from a recorded medium on which signals of images or sounds are continuously recorded so as to constitute a signal recorded line or signal track. In play-back the images or sounds are optically recognized by the width-change of the signal recorded line. A narrow light beam for the play-back is deflected at a predetermined frequency in the direction perpendicular to the signal recorded line, i.e. in the direction of the width of the signal recorded line, in order to perform the optical scanning. The narrow light beam which is reflected or transmitted on the recorded medium surface reaches photo-sensitive elements such as photo-diodes.Type: GrantFiled: November 22, 1976Date of Patent: August 5, 1980Assignee: Fuji Telecasting Co., Ltd.Inventors: Norio Iwasaki, Toshio Satoh, Hiroyuki Ito, Ikuya Koike