Patents by Inventor Toshiro Higuchi

Toshiro Higuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7268167
    Abstract: A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner. A dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel such that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: September 11, 2007
    Assignee: Japan Science and Technology Agency
    Inventors: Toshiro Higuchi, Toru Torii, Takashi Nishisako, Tomohiro Taniguchi
  • Publication number: 20070196397
    Abstract: A method and an apparatus for producing various types of microdroplets. The apparatus has a cross intersection portion at which a first continuous phase, a first dispersion phase, and a second dispersion phase intersect with each other. A first liquid feed device controls the first dispersion phase and a second liquid feed device controls the second dispersion phase. A control device is connected to the first liquid feed device and the second liquid feed device. The first liquid feed device and the second liquid feed device are controlled by a signal from the control device so that microdroplets formed of the first dispersion phase and microdroplets formed of the second dispersion phase are sequentially produced.
    Type: Application
    Filed: March 15, 2005
    Publication date: August 23, 2007
    Applicant: Japan Science and Technology Agency
    Inventors: Toru Torii, Toshiro Higuchi, Takashi Nishisako, Shingo Okushima
  • Publication number: 20060172336
    Abstract: To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
    Type: Application
    Filed: March 30, 2006
    Publication date: August 3, 2006
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Toshiro Higuchi, Toru Torii, Tomohiro Taniguchi, Tetsuo Katayama
  • Publication number: 20060166262
    Abstract: To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
    Type: Application
    Filed: March 30, 2006
    Publication date: July 27, 2006
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Toshiro Higuchi, Toru Torii, Tomohiro Taniguchi, Tetsuo Katayama
  • Publication number: 20060166261
    Abstract: To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate. (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
    Type: Application
    Filed: March 30, 2006
    Publication date: July 27, 2006
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Toshiro Higuchi, Toru Torii, Tomohiro Taniguchi, Tetsuo Katayama
  • Publication number: 20060079584
    Abstract: A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Applicant: Japan Science and Technology Corporation
    Inventors: Toshiro Higuchi, Toru Torii, Takashi Nishisako, Tomohiro Taniguchi
  • Publication number: 20060077755
    Abstract: The present invention provides a process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner. A dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Applicant: Japan Science and Technology Corporation
    Inventors: Toshiro Higuchi, Toru Torii, Takashi Nishisako, Tomohiro Taniguchi
  • Publication number: 20060079585
    Abstract: A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Applicant: Japan Science and Technology Corporation
    Inventors: Toshiro Higuchi, Toru Torii, Takashi Nishisako, Tomohiro Taniguchi
  • Publication number: 20060079583
    Abstract: A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Applicant: Japan Science and Technology Corporation
    Inventors: Toshiro Higuchi, Toru Torii, Takashi Nishisako, Tomohiro Taniguchi
  • Publication number: 20060014894
    Abstract: Monodisperse colored spherical particles each having two separated color regions of two hues, that is, two-colored spherical particles, useful, for example, for displays of characters, graphics, images and the like, the two hues being for reverse display in terms of electricity and magnetism from the viewpoint of good suitability for display are provided. In the production process and the apparatus for producing the colored spherical polymer particles, microchannels are utilized including a first microchannel through which a colored continuous phase comprising a color dye/pigment dispersed in a fluid dispersing medium containing a polymerizable resin component and having colored phases of different hues is transferred, and a second microchannel through which a spheroidizing disperse phase flows.
    Type: Application
    Filed: December 5, 2003
    Publication date: January 19, 2006
    Applicants: Soken Chemical & Engineering Co., Ltd.
    Inventors: Toru Torii, Toshiro Higuchi, Takasi Nisisako, Youichi Takizawa, Takanori Takahashi
  • Patent number: 6947646
    Abstract: An optical axis alignment apparatus 10 has a chuck 13 for holding an optical member 14, a chuck 16 for holding an optical member 15, a pushing mechanism, which pushes the chuck 1 to generate a predetermined frictional force between the optical member 14 and the optical member 15, and actuators 18A to 18D. The actuators 18A to 18D have a piezoelectric element 51b which generates an impulsive inertial force by abrupt extension and contraction.
    Type: Grant
    Filed: February 1, 2002
    Date of Patent: September 20, 2005
    Assignees: Japan Science & Technology Agency, Nano Control Co., Ltd.
    Inventors: Mutsuo Munekata, Toshiro Higuchi
  • Publication number: 20050126480
    Abstract: A solution containing a sample is provided vibration by a vibrating element, the solution is atomized in a status retaining its activities as minute particulate substances, and the solution and/or the atomized minute particulate substances are electrically charged by wires applied a high voltage. Then, the particles are dried out during flying, the particles are deposited onto a substrate grounded by electrostatic force, and to be immobilized in a status keeping its activities.
    Type: Application
    Filed: November 5, 2002
    Publication date: June 16, 2005
    Inventors: Yutaka Yamagata, Toshiro Higuchi, Joon Kim, Kozo Inoue
  • Publication number: 20050064423
    Abstract: To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
    Type: Application
    Filed: January 8, 2003
    Publication date: March 24, 2005
    Inventors: Toshiro Higuchi, Toru Torii, Tomohiro Taniguchi, Tetsuo Katayama
  • Publication number: 20040206409
    Abstract: The air valve includes a valve body for controlling operations to open and close the communication between an air pressure chamber and an air outlet, a piezoelectric element for generating driving force in the form of displacements, and a displacement enlarging mechanism for enlarging the small displacements generated by the piezoelectric element by the principle of a pry and applying the enlarged displacements to the valve body. The enlarged displacements cause a large and sufficient gap to be developed between the air pressure chamber and the air outlet when a voltage is applied to the piezoelectric element. When the applying of voltage to the piezoelectric element is stopped, the resetting force of the piezoelectric element itself causes the gap to be closed quickly.
    Type: Application
    Filed: April 9, 2004
    Publication date: October 21, 2004
    Inventors: Takeshi Yano, Toshiro Higuchi, Kenichi Kudoh, Sze Keat Chee, Tsunehiko Shibata, Norimasa Ikeda
  • Publication number: 20040134854
    Abstract: A liquid particulate-handling method and device, in which the evaporation of the droplets is prevented and therefore the handing of the droplets is appropriately performed, are provided.
    Type: Application
    Filed: August 25, 2003
    Publication date: July 15, 2004
    Inventors: Toshiro Higuchi, Toru Torii, Tomohiro Taniguchi
  • Publication number: 20040068019
    Abstract: The present invention provides a process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner.
    Type: Application
    Filed: August 22, 2003
    Publication date: April 8, 2004
    Inventors: Toshiro Higuchi, Toru Torii, Takashi Nishisako, Tomohiro Taniguchi
  • Publication number: 20040052469
    Abstract: An optical axis alignment apparatus 10 has a chuck 13 for holding an optical member 14, a chuck 16 for holding an optical member 15, a pushing mechanism, which pushes the chuck 1 to generate a predetermined frictional force between the optical member 14 and the optical member 15, and actuators 18A to 18D. The actuators 18A to 18D have a piezoelectric element 51b which generates an impulsive inertial force by abrupt extension and contraction.
    Type: Application
    Filed: July 29, 2003
    Publication date: March 18, 2004
    Applicants: Japan Science and Technology Corporation, Nano Control Co., LTD
    Inventors: Mutsuo Munekata, Toshiro Higuchi
  • Publication number: 20040039624
    Abstract: An activity plan generation unit generates an activity plan for each salesperson based on an action pattern including a work objective and performance time obtained by analyzing a sales activity of a high performance salesperson, registers the plan in an activity plan DB, and notifies the plan to the salesperson and his/her supervisor. An information collection/registration unit stores an activity achievement input by a salesperson in an activity achievement DB. A progress management unit determines whether there is difference between an activity plan of a salesperson stored in the activity plan DB and an activity achievement stored in the activity achievement DB. When determining that there is difference between them, the progress management unit makes the activity plan generation unit again select an appropriate action pattern and correct the activity plan, and notifies the difference to the supervisor of the salesperson.
    Type: Application
    Filed: July 11, 2003
    Publication date: February 26, 2004
    Inventors: Toyoji Ikezawa, Yasuaki Misawa, Hiroumi Taruta, Nobuyuki Azuma, Toshiro Higuchi, Shoichiro Kouda, Tadaaki Suga
  • Publication number: 20030215121
    Abstract: In order to make observation of localizations of in vivo expressed genes possible in an entire individual living organism such as animals, and plants, a living genetic recombinant specimen containing a marker that can be detected at the time when specific genes are expressed is sequentially severed, sectional images each of which corresponds to an image of sections severed are photographed in every scissions of the living specimen, and three-dimensional observation of the living specimen is implemented on the basis of the images photographed in every scissions described above, whereby three-dimensional localizations of expressed genes are observed in the living specimen.
    Type: Application
    Filed: March 4, 2003
    Publication date: November 20, 2003
    Inventors: Hideo Yokota, Sakiko Nakamura, Atsushi Yoshiki, Akitake Makinouchi, Ryutaro Himeno, Toshiro Higuchi
  • Patent number: 6555209
    Abstract: A method of manufacturing a multilayer wiring board comprising a step of forming an upper wiring layer (27), a part thereof being electrically connected to a pillar-shaped metallic body (24a), after he pillar-shaped metal body (24a) is formed on a lower wiring layer (22) is characterized in that the step of forming the metallic body includes a sub-step of forming a plating layer (24) constituting the metallic body, a sub-step of forming a mask layer (25) on the surface where the metal body is formed, of the plating layer, and a sub-step of etching the plating layer. The manufacture can be carried out with simple equipment combination of conventional steps and the wiring layer can be made fine.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: April 29, 2003
    Assignee: Daiwa Co., Ltd.
    Inventors: Eiji Yoshimura, Toshiro Higuchi