Patents by Inventor Totada R. Shantha

Totada R. Shantha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160074480
    Abstract: A Safe and effective treatment methods to cure and curtail tuberculosis affliction described using high dose Vitamin C, and other known anti-mycobacterium tuberculosis drugs especially rifampicin administered intravenously for 6 weeks instead of 6 to 24 months of conventional treatment. Insulin is administered to induce moderate hypoglycemia to augment and add effectiveness of anti-tuberculosis drugs and Vitamin C. Invention also delivers the drugs directly to a tuberculin lesion through a catheter. An embodiment of the invention uses a nebulizer and other methods of administration of Vitamin C with anti-tuberculosis drugs, interferon Y?, Coley's vaccine, dinitrophenol hyperthermia, ozone therapy, Hydrogen peroxide therapy and artemisinin, combined with oxygen supplementation including autohemotherapy with ozone, hyperbaric therapy, and hypertheramia to increase the respiration of the M. tuberculosis bacteria which has a killing effect.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Inventor: Totada R. SHANTHA
  • Patent number: 9254219
    Abstract: The present invention is a safe, inexpensive, easy to use and effective anti-snoring and anti-sleep apnea treatment device. The device has a vertical and horizontal bar. The horizontal bar is placed inside the mouth, behind or between the molar teeth with palatine and tongue shelves to prevent snoring and movement of the tongue backwards. The device is tethered to the hard palate by vacuum cups to prevent the movement of the tongue backwards during sleep to prevent sleep apnea. The proximal end of the vertical bar is anchored to string at the distal end with hook and loop fabric closure adhesive attachment and to the lips outside the mouth to prevent the accidental swallowing and aspiration of the device; and at the same time holds the tongue and device firmly in the mouth. The device is provided with canula with three way stopcocks to deliver supplemental oxygen and therapeutic agents.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: February 9, 2016
    Inventor: Totada R. Shantha
  • Patent number: 9072613
    Abstract: A device for snoring and obstructive sleep apnea treatment has an oral elastic glove portion adapted to removably cover a free moving portion of a user's tongue. Three vacuum suction cups are used to attach the device to the hard palate and the dorsal and ventral surfaces of the tongue in order to hold the device in place without allowing the tongue to move backwards. A vacuum creating cannula and a syringe attached to a tip of the device to create a vacuum once the device in positioned in the user's mouth. In addition, a balloon is provided to prevent soft palate vibrations. A skin attachment pad is removably attached to the user's face close to the mouth and holds the end of a string provided to secure the tongue glove from moving during sleep or be accidentally swallowed.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: July 7, 2015
    Inventor: Totada R Shantha
  • Publication number: 20150080785
    Abstract: This invention describes the administration of multiple therapeutic agents with insulin in conjunction with bexarotene, ketamine, monoclonal antibodies Etanercept, IGF-1, and acetylcholine esterase inhibitors physostigmine, for treatment of Alzheimer's disease and other neurodegenerative diseases. Insulin, improves memory; also augments and amplifies the effects of the adjuvant therapeutic agents (paracrine and intracrine effects) and consequently reduces the ? amyloid, its soluble precursors, prevents damage to the neuronal skeletal network (taupathy), and blocks glutamate excitotoxicity, reduces brain inflammation, prevents apoptosis, and increases the acetylcholine levels in the neurons and synapses; by using a combination of insulin, bexarotene, ketamine, Etanercept, IGF-1, and physostigmine therapeutic agents.
    Type: Application
    Filed: September 19, 2014
    Publication date: March 19, 2015
    Inventor: Totada R. Shantha
  • Publication number: 20150073330
    Abstract: This invention describes the administration of multiple therapeutic agents with insulin in conjunction with bexarotene, ketamine, monoclonal antibodies Etanercept, IGF-1, and acetylcholine esterase inhibitors physostigmine, for treatment of Alzheimer's disease and other neurodegenerative diseases. Insulin, improves memory; also augments and amplifies the effects of the adjuvant therapeutic agents (paracrine and intracrine effects) and consequently reduces the ? amyloid, its soluble precursors, prevents damage to the neuronal skeletal network (taupathy), and blocks glutamate excitotoxicity, reduces brain inflammation, prevents apoptosis, and increases the acetylcholine levels in the neurons and synapses; by using a combination of insulin, bexarotene, ketamine, Etanercept, IGF-1, and physostigmine therapeutic agents.
    Type: Application
    Filed: September 19, 2014
    Publication date: March 12, 2015
    Inventor: Totada R. Shantha
  • Patent number: 8853978
    Abstract: An electric motor drive system capture and control apparatus for energy savings has an alternating current power source electrically connected to a direct current motor. A power rectifier diode rated for the alternating current power source and the direct current motor is electrically connected in a reverse bias mode between the negative supply wire of the direct current motor and a grounded neutral conductor of the alternating current power source. A ground wire is electrically connected to the direct current motor and cross connected to a hot lag wire of the alternating current power source. The direct current motor is voltage matched to the alternating current power source. A transformer is electrically connected to the alternating current power source and the direct current motor. The system may be scaled to work with a power grid or for use in a vehicle.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: October 7, 2014
    Inventors: Steven Ross Hardison, Totada R Shantha
  • Publication number: 20140184111
    Abstract: An electric motor drive system capture and control apparatus for energy savings has an alternating current power source electrically connected to a direct current motor. A power rectifier diode rated for the alternating current power source and the direct current motor is electrically connected in a reverse bias mode between the negative supply wire of the direct current motor and a grounded neutral conductor of the alternating current power source. A ground wire is electrically connected to the direct current motor and cross connected to a hot lag wire of the alternating current power source. The direct current motor is voltage matched to the alternating current power source. A transformer is electrically connected to the alternating current power source and the direct current motor. The system may be scaled to work with a power grid or for use in a vehicle.
    Type: Application
    Filed: March 5, 2014
    Publication date: July 3, 2014
    Inventors: Steven Ross Hardison, Totada R. Shantha
  • Publication number: 20140035460
    Abstract: A high efficiency light bulb has an outer globe with a base and a detachable bulb portion. The base has a base connection portion with a screw base and a control circuit with transformer for controlling and conveying electric power from the screw base to a quartz tungsten filament. The detachable bulb portion has an outer globe and an inner globe. At least the inner globe has a transparent infrared heat reflecting coating to improve efficiency by retaining heat within and reflecting the heat back on the filament. In another embodiment, the bulb and base are not detachable and the whole bulb is replaced when it reaches the end of its usefulness. A non-reactive gas such as krypton, bromine or xenon, for example, is used to fill the bulbs.
    Type: Application
    Filed: July 25, 2013
    Publication date: February 6, 2014
    Inventor: Totada` R. Shantha
  • Publication number: 20140012182
    Abstract: This invention describes the administration of multiple therapeutic agents with insulin in conjunction with bexarotene, ketamine, monoclonal antibodies Etanercept, IGF-1, and acetylcholine esterase inhibitors physostigmine, for treatment of Alzheimer's disease and other neurodegenerative diseases. Insulin, improves memory; also augments and amplifies the effects of the adjuvant therapeutic agents (paracrine and intracrine effects) and consequently reduces the ? amyloid, its soluble precursors, prevents damage to the neuronal skeletal network (taupathy), and blocks glutamate excitotoxicity, reduces brain inflammation, prevents apoptosis, and increases the acetylcholine levels in the neurons and synapses; by using a combination of insulin, bexarotene, ketamine, Etanercept, IGF-1, and physostigmine therapeutic agents.
    Type: Application
    Filed: July 18, 2013
    Publication date: January 9, 2014
    Applicant: Wedge Therapeutics, LLC
    Inventor: Totada R. Shantha
  • Publication number: 20120323214
    Abstract: This invention describes the administration of multiple therapeutic agents with insulin in conjunction with bexarotene, ketamine, monoclonal antibodies Etanercept, IGF-1, and acetylcholine esterase inhibitors physostigmine, for treatment of Alzheimer's disease and other neurodegenerative diseases. Insulin, improves memory; also augments and amplifies the effects of the adjuvant therapeutic agents (paracrine and intracrine effects) and consequently reduces the ? amyloid, its soluble precursors, prevents damage to the neuronal skeletal network (taupathy), and blocks glutamate excitotoxicity, reduces brain inflammation, prevents apoptosis, and increases the acetylcholine levels in the neurons and synapses; by using a combination of insulin, bexarotene, ketamine, Etanercept, IGF-1, and physostigmine therapeutic agents.
    Type: Application
    Filed: May 16, 2012
    Publication date: December 20, 2012
    Inventor: Totada R Shantha
  • Publication number: 20120255561
    Abstract: A device for snoring and obstructive sleep apnea treatment has an oral elastic glove portion adapted to removably cover a free moving portion of a user's tongue. Three vacuum suction cups are used to attach the device to the hard palate and the dorsal and ventral surfaces of the tongue in order to hold the device in place without allowing the tongue to move backwards. A vacuum creating cannula and a syringe attached to a tip of the device to create a vacuum once the device in positioned in the user's mouth. In addition, a balloon is provided to prevent soft palate vibrations. A skin attachment pad is removably attached to the user's face close to the mouth and holds the end of a string provided to secure the tongue glove from moving during sleep or be accidentally swallowed.
    Type: Application
    Filed: June 22, 2012
    Publication date: October 11, 2012
    Inventor: Totada R. Shantha
  • Publication number: 20120234332
    Abstract: A anti-snoring and anti-obstructive sleep apnea apparatus has a plate or metal frame tongue shelf splint to prevent the flaccid tongue falling back, a palate shelf splint projection to elevate the soft palate and prevents its vibration, incisors teeth receptacles or pockets sockets for jaw displacer to hold the mandible moved forwards, and to prevent it falling back held between the bite block, catheter-tubing to administer oxygen supplementation from the external source which reduces air turbulence and promotes nasal breathing, a submental suprahyoid muscle stimulator placed below the tongue, and above the mucous membrane. An injection port is provided to administer any therapeutic agents and local anesthetics to reduce the sensitivity of the tongue and oral cavity mucus membrane lining to the foreign objects. This device is used to deliver therapeutic agents to prevent and to treat halitosis and various diseases.
    Type: Application
    Filed: June 1, 2012
    Publication date: September 20, 2012
    Inventor: Totada R. Shantha
  • Publication number: 20120234331
    Abstract: The present invention is a safe, inexpensive, easy to use and effective anti-snoring and anti-sleep apnea treatment device. The device has a vertical and horizontal bar. The horizontal bar is placed inside the mouth, behind or between the molar teeth with palatine and tongue shelves to prevent snoring and movement of the tongue backwards. The device is tethered to the hard palate by vacuum cups to prevent the movement of the tongue backwards during sleep to prevent sleep apnea. The proximal end of the vertical bar is anchored to string at the distal end with hook and loop fabric closure adhesive attachment and to the lips outside the mouth to prevent the accidental swallowing and aspiration of the device; and at the same time holds the tongue and device firmly in the mouth. The device is provided with canula with three way stopcocks to deliver supplemental oxygen and therapeutic agents.
    Type: Application
    Filed: June 1, 2012
    Publication date: September 20, 2012
    Inventor: Totada R. Shantha
  • Publication number: 20120203141
    Abstract: A therapeutic device and method for blocking pain in a patient's digit includes a ring-like vibratory element adapted to be fitted about the digit temporarily and controller coupled to the ring-like vibratory element for controlling its operation. By applying vibration to the patient's digit, pain transmission is blocked or lessened along the digit, allowing the patient or a caregiver to provide treatment to the digit with reduced pain, such as when a diabetic's finger is to be stuck for drawing blood for a blood sugar measurement). Moreover, if the digit is injured, the present invention can provide pain relief from the injury as well. Further, the invention can be applied to the digit in combination with other pain-reducing therapies, such as the application of ice, the application of topical analgesics, the application of local anesthetics, etc. The controller includes an on/off control switch and a switch for controlling the vibratory frequency.
    Type: Application
    Filed: February 7, 2011
    Publication date: August 9, 2012
    Inventors: Totada R. SHANTHA, Jessica G. SHANTHA, Erica M. SHANTHA, Lauren A. SHANTHA, Usha MARTIN
  • Patent number: 8226228
    Abstract: Cooling and heating eyeglasses have peltier chips mounted around at least a portion of the perimeter of the lenses that provides a cooling affect that reduces eyestrain and provides cooling relief to the user. A battery pack provides the electrical energy needed to energize the peltier chips. The battery pack is connected to a neck strap that allows the user to comfortably support the batteries. In another embodiment, a plurality of smaller batteries are used and disposed within the frame eliminating the need for an external battery pack. In another embodiment, side shields are also provide with peltier chips to further control the temperature especially around the user's eyes. Because the peltier can also provide heating, a user can also select heating if preferred. The cooling and heating glasses can be used for prevention and treatment of several eye diseases and oculopathies.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: July 24, 2012
    Inventors: Totada R Shantha, Jessica Shantha
  • Patent number: 8206336
    Abstract: Described herein are transdermal delivery devices composed of at least one resealable injection port and at least one local anesthetic reservoir. The device effectively delivers anesthetic to the skin of the subject prior to puncturing the skin by syringes, needle sticks, or other instruments intended to be inserted into the skin. In addition, the transdermal delivery device may include a single use patch that does not include a local anesthetic refill port. The devices are used in combination with an electromotive force in order to enhance pain reduction when a subject is injected with a needle. Devices for imparting an electromotive force to a subject are also described herein.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: June 26, 2012
    Inventor: Totada R. Shantha
  • Publication number: 20120156202
    Abstract: A method for treating age related macular degeneration (AMD) using an insulin preparation applied topically to the conjunctival sac of the affected eye. Another aspect of this invention is using antiangiogenic adjuvant therapeutic agents such as bevacizumab, ranibizumab, pegaptanib, etanercept, instilled in to the afflicted eye conjunctival sac with insulin to prevent further formation of new blood vessels, and shrink the existing pathologically formed blood vessels and reduce the edema in wet AMD. This method incorporates putting the patients on low fat diet, aerobic exercise, ketamine-a NMDA blocker, reducing the blood cholesterol using adjuvant therapeutic agents selected from Statins, that are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A, (i.e. HMG-Co A) reductase which in turn reduce drusen formation that leads to AMD, combined with insulin ophthalmic drops.
    Type: Application
    Filed: February 28, 2012
    Publication date: June 21, 2012
    Inventors: Totada R. Shantha, Jessica Shantha, Erica Maya Shantha
  • Patent number: D849233
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: May 21, 2019
    Assignee: Wedge Therapeutics, LLC
    Inventors: Totada R. Shantha, Robert Wieden
  • Patent number: D849234
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: May 21, 2019
    Assignee: Wedge Therapeutics, LLC
    Inventors: Totada R. Shantha, Robert Wieden
  • Patent number: D885558
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: May 26, 2020
    Assignee: Wedge Therapeutics LLC
    Inventors: Totada R. Shantha, Robert Wieden