Abstract: Cooling and heating eyeglasses have peltier chips mounted around at least a portion of the perimeter of the lenses that provides a cooling affect that reduces eyestrain and provides cooling relief to the user. A battery pack provides the electrical energy needed to energize the peltier chips. The battery pack is connected to a neck strap that allows the user to comfortably support the batteries. In another embodiment, a plurality of smaller batteries are used and disposed within the frame eliminating the need for an external battery pack. In another embodiment, side shields are also provide with peltier chips to further control the temperature especially around the user's eyes. Because the peltier can also provide heating, a user can also select heating if preferred. The cooling and heating glasses can be used for prevention and treatment of several eye diseases and oculopathies.

Abstract: Described herein are transdermal delivery devices composed of at least one resealable injection port and at least one local anesthetic reservoir. The device effectively delivers anesthetic to the skin of the subject prior to puncturing the skin by syringes, needle sticks, or other instruments intended to be inserted into the skin. In addition, the transdermal delivery device may include a single use patch that does not include a local anesthetic refill port. The devices are used in combination with an electromotive force in order to enhance pain reduction when a subject is injected with a needle. Devices for imparting an electromotive force to a subject are also described herein.

Abstract: A method for treating age related macular degeneration (AMD) using an insulin preparation applied topically to the conjunctival sac of the affected eye. Another aspect of this invention is using antiangiogenic adjuvant therapeutic agents such as bevacizumab, ranibizumab, pegaptanib, etanercept, instilled in to the afflicted eye conjunctival sac with insulin to prevent further formation of new blood vessels, and shrink the existing pathologically formed blood vessels and reduce the edema in wet AMD. This method incorporates putting the patients on low fat diet, aerobic exercise, ketamine-a NMDA blocker, reducing the blood cholesterol using adjuvant therapeutic agents selected from Statins, that are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A, (i.e. HMG-Co A) reductase which in turn reduce drusen formation that leads to AMD, combined with insulin ophthalmic drops.

Abstract: The invention is for a safe and effective method of administering an opthalmological therapeutic agent for the treatment of night blindness and improving night vision, using insulin, and chlorin e6, preparations instilled into the conjunctival sac as ophthalmic drops. Night blindness and decreased night vision is associated with retinal diseases such as dry age related macular degeneration, retinitis pigmentosa and other such related eye diseases by using insulin, chlorin e6, ketamine, and monoclonal antibodies and IGF-1. The ophthalmic preparations may be supplemented with oral intake of various retinal photoreceptors vision supporting lutein, vitamin A, Zeaxanthin, Omega 3 Oils and other nurticeuticals. They may also be supplemented with cholesterol lowering statins in the elderly with high blood cholesterol to prevent eye diseases such as AMD contributing to night vision and night blindness.

Abstract: A safe and effective treatment to curtail and cure autism spectrum disorders has been described in this invention using insulin, IGF-1, with multiple known adjuvant therapeutic agents, as well as other pharmaceutical, biochemical, nurticeuticals, and biological agents or compounds delivered through the olfactory mucosal region of the nose and external auditory meatus.

Abstract: A method of treatment of retinitis pigmentosa using a medically effective dose of insulin, IGF-1, and chlorin e6 topically applied to the conjunctival sac of the afflicted eye. The combination of these is very effective in treating retinitis pigmentosa and may be repeated as directed by a medical practitioner. The method includes preparing the dosage and filling an eye dropper with the compound, then having the patient lie in a supine position while administering the dosage. The patient remains in this position for 5 minutes to ensure absorption of the compound. In one embodiment, single use eye droppers are provided to simplify treatment. The particular dosage is adjusted to take individual metabolisms into account. A thorough examination of the patient's eyes should be done prior to treatment.

Abstract: A multi-use knife scraper has a handle portion which pivotally retains a blade holder at one end. A single-edged blade is held therein and can be positioned between a knife position which is generally parallel to the handle and a scraper position which is generally perpendicular to the handle. In one embodiment, the blade can be rotated to fit within the handle to secure the blade safely. One embodiment uses single-edged razor blades and another embodiment utilizes utility blades. The knife position allows the knife to be used as a box cutter and general purpose knife while the scraper position allows scraping and other uses where the orientation of the blade needs to be perpendicular to the handle.

Abstract: The invention relates to a method of insulin eye drops for treating dry eye syndrome due to any and all etiological factors (Keratoconjunctivitis sicca), including Sjogren's syndrome, Meibomian gland dysfunction (MGD) and other glandular malfunction in the eye lids, lacrimal glands, cornea, conjunctiva, and exposed scleral surface of the eye. It is treated with Insulin and/or IGF-I with or without known anti-dry eye syndrome therapeutic, pharmaceutical, biochemical and biological agents or compounds.

Abstract: Cooling and heating eyeglasses have peltier chips mounted around at least a portion of the perimeter of the lenses that provides a cooling affect that reduces eyestrain and provides cooling relief to the user. A battery pack provides the electrical energy needed to energize the peltier chips. The battery pack is connected to a neck strap that allows the user to comfortably support the batteries. In another embodiment, a plurality of smaller batteries are used and disposed within the frame eliminating the need for an external battery pack. In another embodiment, side shields are also provide with peltier chips to further control the temperature especially around the user's eyes. Because the peltier can also provide heating, a user can also select heating if preferred. The cooling and heating glasses can be used for prevention and treatment of several eye diseases and oculopathies.

Abstract: A safe and effective treatment for glaucoma for mammalian species comprises the steps of applying insulin and/or insulin like growth factors (IGF-1) to an eye. In addition to the insulin, another therapeutic agent may be applied to enhance the activity of the insulin. The therapeutic agent may be a pharmaceutical agent or a biochemical pharmaceutical agent. The therapeutic agents include prostaglandin analogs, topical beta-adrenergic receptor antagonists-? blockers, Alpha2-adrenergic agonists hair growth therapeutic agents, beta2-agonist action agents, parasympathomimetic miotic agents, carbonic anhydrase inhibitors, and Physostigmine. In another embodiment, a combination of at least two agents are applied to the eye. To enhance the effect of the insulin, uptake facilitators may be used. Additionally, an antibacterial agent may be applied to control bacterial infection.

Abstract: A method of enhancing eyelash and eye brow hair growth utilizes insulin and/or IFG-1 alone or in combination with other known hair growth promoting therapeutic, pharmaceutical, biochemical and biological agents to increase the effect of various therapeutic hair regrowth strategies to enhance eyelash and eye brow hair growth.

Abstract: Described herein are transdermal delivery devices composed of at least one resealable injection port and at least one local anesthetic reservoir. The device effectively delivers anesthetic to the skin of the subject prior to puncturing the skin by syringes, needle sticks, or other instruments intended to be inserted into the skin. In addition, the transdermal delivery device may include a single use patch that does not include a local anesthetic refill port. The devices are used in combination with an electromotive force in order to enhance pain reduction when a subject is injected with a needle. Devices for imparting an electromotive force to a subject are also described herein.

Abstract: A snoring and obstructive sleep apnea prevention and treatment device has an oral device portion with a centrally disposed plate portion. The plate portion has a suction cup on its tongue facing side which helps hold it in place and to keep the tongue from moving back towards the throat, thus preventing snoring and sleep apnea. A hood portion fits around the tip of the tongue further preventing the tongue from sliding back into a user's throat. In one embodiment, an inflatable balloon portion is provided to prevent soft tissue from contacting portions of the tongue. In another embodiment, a plate is used in place of the balloons. Additionally, oxygen may be supplied to a posterior portion of the device. Dental adhesives such as denture adhesive may be used to further restrict movement.

Abstract: A leg supporting device for use behind a head rest for air and vehicular travel has a head rest support portion that fits over a head rest of a forwardly positioned seat and supports a back flap portion that hangs down behind the forwardly positioned seat. A pair of adjustment straps adjustably attach to the back flap portion and supports a foot support portion. A user slips one or both of their feet into the foot support portion and then adjusts the adjustment straps to support their feet at a desired height and position. The foot support portion handles to carry it. In use, the leg supporting device can be folded and placed within the foot support portion and carried using the handles until needed. One embodiment includes pockets for holding drinks, computer, and other carry-on items. A leg massage unit may be built in for additional relief.

Abstract: A leg supporting device for use behind a head rest for air and vehicular travel has a head rest support portion that fits over a head rest of a forwardly positioned seat and supports a back flap portion that hangs down behind the forwardly positioned seat. A pair of adjustment straps adjustably attach to the back flap portion and supports a foot support portion. A user slips one or both of their feet into the foot support portion and then adjusts the adjustment straps to support their feet at a desired height and position. The foot support portion handles to carry it. In use, the leg supporting device can be folded and placed within the foot support portion and carried using the handles until needed. One embodiment includes pockets for holding drinks, computer, and other carry-on items. A leg massage unit may be built in for additional relief.

Abstract: A simple, safe and effective invention devices for treating bags under the eyes pressure exerting glasses devices, compress badges, bag pressure adhesive strips, cosmetic pressure adhesive strips; to be put on to prevent, and to reduce the bags under the eyes. They are designed to apply antiwrinkle and other cosmetic and therapeutic agents such as hormones, known therapeutic agents, as well as other pharmaceutical, biochemical, nurticeuticals and biological agents, or compounds to enhance the health and beauty of the eye, strengthen the lower eye lids and to treat many oculopathies which can contribute to the condition. They can be used for the eye makeup cosmetically as adjuvant to eye makeup. The electrical stimulation and electromotive force are incorporated in the invention to strengthen the lower eye lids muscles, to improve the health of the eye lids skin and for the delivery of therapeutic agents to treat various oculopathies.

Abstract: A light with replaceable light source has a base that fits within a standard light socket. The base has a threaded portion that is adapted to receive a complementary threaded portion in an outer protective bulb. The base holds a plug used to removably attach a sealed inner bulb. There is a plurality of holes in the outer bulb to allow air to flow therein. The sealed inner bulb is replaced as needed. Additionally, the inner sealed bulb may be an incandescent, CFL or LED. In one embodiment, a sensor is provided to provide automatic operation. In another embodiment, three-way functionality is provided. Replacement sealed bulbs may be provided in a bulk pack to further economize.

Abstract: A modular lighting apparatus includes a replaceable bulb assembly, an adapter, and a mechanical and electrical connector assembly that removably connects the bulb assembly to the adapter for use. The bulb assembly includes a light-emitting component mounted to a body. In example embodiments the light-emitting component includes spiral-tube CFLs, low-profile transverse CFL tubes, and omni-directional LED arrays. The adapter includes a standard screw base mounted to a body that houses an electronic ballast. In this way, the bulb assembly can be removed from the adapter and replaced, while reusing the electronic ballast in the adapter. And the screw-base adapter allows the reuse of the electronic ballast in standard screw-socket household light fixtures. In addition, the reusable adapter base also may be provided with an integral photocell for light-based control of the lighting apparatus without increasing the overall height of the composite lighting apparatus.

Abstract: A method for treating age related macular degeneration uses insulin preparation applied topically in a therapeutically effective amount to an affected conjunctival sac of the eye. The topically effective dose is delivered to the fovea centralis and macula lutea. In other embodiments, additional therapeutic, pharmaceutical, biochemical, nutriceutical, biological (monoclonal antibodies and others) agent or compound, and organic and inorganic agents are also applied to the afflicted site through the conjunctival sac and choroidal vascular system of the eye. IGF-1 may be applied as well with or without insulin to treat ARMD.