Patents by Inventor Trimurtulu Golakoti

Trimurtulu Golakoti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cryptophycins from synthesis
    Patent number: 6013626
    Abstract: A cryptophycin compound is provided having the structure: ##STR1## Further provided are methods of producing cryptophycins by total synthesis and methods of using cryptophycins in pharmaceuticals. It is a further object of this invention to use cryptophycins to inhibit the proliferation of mammalian cells. Moreover, methods of using cryptophycins to treat neoplasia is also provided.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: January 11, 2000
    Assignees: The University of Hawaii, Wayne State University
    Inventors: Richard E. Moore, Marcus A. Tius, Russell A. Barrow, Jian Liang, Thomas H. Corbett, Frederick A. Valeriote, Trimurtulu Golakoti, Thomas K. Hemscheidt
  • Cryptophycins
    Patent number: 5955423
    Abstract: A cryptophycin compound is provided having the structure: ##STR1## Further provided are methods for producing novel cryptophycins from the Nostoc sp. of blue-green algae (cyanobacteria). Pharmaceutical compositions comprising novel cryptophycins are also provided, as are methods for using cryptophycins to inhibit the proliferation of hyperproliferative cells. Further provided are methods for using cryptophycins to inhibit the proliferation of hyperproliferative cells with drug resistant phenotypes, and to treat pathological conditions, such as neoplasia.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 21, 1999
    Assignees: The University of Hawaii, Wayne State University
    Inventors: Richard E. Moore, Charles D. Smith, Gregory M. L. Patterson, Susan L. Mooberry, Thomas H. Corbett, Frederick A. Valeriote, Trimurtulu Golakoti
  • Cryptophycins
    Patent number: 5952298
    Abstract: A cryptophycin compound is provided having the structure: ##STR1## Further provided are methods for producing novel cryptophycins from the Nostoc sp. of blue-green algae (cyanobacteria). Pharmaceutical compositions comprising novel cryptophycins are also provided, as are methods for using cryptophycins to inhibit the proliferation of hyperproliferative cells. Further provided are methods for using cryptophycins to inhibit the proliferation of hyperproliferative cells with drug resistant phenotypes, and to treat pathological conditions, such as neoplasia.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 14, 1999
    Assignees: The University Of Hawaii, Wayne State University
    Inventors: Richard E. Moore, Charles D. Smith, Gregory M.L. Patterson, Susan L. Mooberry, Thomas H. Corbett, Frederick A. Valeriote, Trimurtulu Golakoti