Abstract: A cooling bed system is configured to provide a cooling airflow around a patient suffering from heat exhaustion, heat stroke and or burns. A cooling bed system produces an airflow over a patient and preferably an airflow from both above and below the patient to more effectively and quickly cool the patient A cooling bed system may also include a liquid dispenser that creates mist that is carried by the airflow to further cool the patient. A patient may be supported by a platform having a plurality of openings to allow airflow and mist to pass therethrough. A controller controls the airflow rate and/or temperature of the air, and may also control the liquid dispensing rate and/or temperature of the liquid as a function of an input from a temperature sensor to effectively and safely cool the patient.

Abstract: The invention relates to an eye mask for treating dry eyes and other eye conditions related to blepharitis or meibomian gland dysfunction. The eye mask acts as a warm compress which ensures the eyelids are heated to expedite eyelid expression to balance out the tear film and treat dry eyes. In one embodiment, an eye mask for treating an ocular condition includes: a fabric having a first layer and a second layer opposite the first layer; and a heat diffusing fill material enclosed between the first and the second layers. The first layer and the second layer are stitched together substantially along their edges. The fill material is configured to deliver a moist heat to an ocular surface.

Abstract: The invention involves forceps having rounded grasping tips. The rounded tips are configured to avoid puncturing an amniotic membrane during insertion over an ocular surface for the treatment of dry eye disease and inflammation of the eyes and to avoid injuring the conjunctiva during removal of an amniotic membrane from the ocular surface. The forceps have grasping tips at its distal end, wherein one of the grasping tips has a notch on its inside surface. The dimensions of the notch are configured to permit an eye doctor to securely and safely grasp a lip of an amniotic membrane insert for better insertion and removal from an ocular surface.

Abstract: Compositions and methods for treating skin redness. According to an embodiment, the invention is a topical skin care composition having a dermatologically acceptable vehicle, such as, water and a plurality of ingredients dissolved in the vehicle. The ingredients include: a blend of natural oils; a plurality of vitamins; and 0.1-1 wt % salicyloyl phytosphingosine. The composition is unsuitable for application on the eyelids or eye area. The blend of natural oils includes: aloe barbadensis leaf juice extract; cocos nucifera (coconut oil); hydrolyzed glycosaminoglycans; and caprylic/capric triglycerides. The plurality of vitamins is selected from a group consisting of vitamin C, vitamin E, salts/derivatives of vitamin C and vitamin E, and mixtures thereof. In one aspect, the plurality of vitamins includes: sodium ascorbyl phosphate; disodium lauriminodipropionate tocopheryl phosphate; and jojoba oil.

Abstract: A cooling bed system is configured to provide a cooling airflow around a patient suffering from heat exhaustion, heat stroke and or burns. A cooling bed system produces an airflow over a patient and preferably an airflow from both above and below the patient to more effectively and quickly cool the patient. A cooling bed system may also include a liquid dispenser that creates mist that is carried by the airflow to further cool the patient. A patient may be supported by a platform having a plurality of openings to allow airflow and mist to pass therethrough. A controller controls the airflow rate and/or temperature of the air, and may also control the liquid dispensing rate and/or temperature of the liquid as a function of an input from a temperature sensor to effectively and safely cool the patient.

Abstract: An anti-allergenic composition comprising from about 0.01% to about 50% by weight of a polyphenol, from about 0.01% to about 50% by weight of a terpene compound, and from about 0.001% to about 10% by weight of a glycolipid. The polyphenol has a flavanol derivative. The terpene compound can be selected from the group consisting of a terpene, terpinene, a terpene derivative and combinations thereof. In an embodiment, the sphingolipid comprises about 0.2% phytosphingosine.

Abstract: Compositions and methods for treating skin redness. According to an embodiment, the invention is a topical skin care composition having a dermatologically acceptable vehicle, such as, water and a plurality of ingredients dissolved in the vehicle. The ingredients include: a blend of natural oils; a plurality of vitamins; and 0.1-1 wt % salicyloyl phytosphingosine. The composition is unsuitable for application on the eyelids or eye area. The blend of natural oils includes: aloe barbadensis leaf juice extract; cocos nucifera (coconut oil); hydrolyzed glycosaminoglycans; and caprylic/capric triglycerides. The plurality of vitamins is selected from a group consisting of vitamin C, vitamin E, salts/derivatives of vitamin C and vitamin E, and mixtures thereof. In one aspect, the plurality of vitamins includes: sodium ascorbyl phosphate; disodium lauriminodipropionate tocopheryl phosphate; and jojoba oil.

Abstract: A portable microorganism sanitation system produces UV light and air treatment for treating an enclosed space, such as a room. A portable microorganism sanitation system incorporates a plurality of UV light sources configured around a lamp tower having reflective surfaces to produce emitted UV and reflected UV light in a wide range of angles. This wide range of angles of the emitted and reflected UV light enables more complete and direct impingement of UV light on surfaces in the enclosure or room. The portable microorganism sanitation system also incorporates active air treatment, wherein an air moving device draws airflow into a conduit inside of the lamp tower and then through airflow outlets. The airflow outlets are configured to expose the outlet airflow to the UV light sources, thereby treating the airflow to destroy microorganism therein. Photocatalyst may be configured on the surfaces of the lamp tower to promote microorganism destruction.

Abstract: A portable microorganism sanitation system produces UV light and air treatment for treating an enclosed space, such as a room. A portable microorganism sanitation system incorporates a plurality of UV light sources configured around a lamp tower having reflective surfaces to produce emitted UV and reflected UV light in a wide range of angles. This wide range of angles of the emitted and reflected UV light enables more complete and direct impingement of UV light on surfaces in the enclosure or room. The portable microorganism sanitation system also incorporates active air treatment, wherein an air moving device draws airflow into a conduit inside of the lamp tower and then through airflow outlets. The airflow outlets are configured to expose the outlet airflow to the UV light sources, thereby treating the airflow to destroy microorganism therein. Photocatalyst may be configured on the surfaces of the lamp tower to promote microorganism destruction.

Abstract: A convenient all-in-one kit for cleansing the eyelids and treating bacterial blepharitis contains one or more fabric pads pre-moistened with a therapeutically effective amount of a hypochlorous acid-based composition. The kit can further include an eyelid cleanser composition as a kit component. The eyelid cleanser composition can be selected from a group consisting of a solution, a foam, a gel, a spray, a lotion, a suspension, an emulsion, an ointment and combinations thereof. The kit can further include one or more fabric pads or wipes impregnated/pre-moistened with the eyelid cleanser composition.

Abstract: Systems, methods, and kits useful for cleansing the eyelids and maintaining eyelid hygiene are disclosed. In one embodiment, a system for treating or cleansing an ocular region is disclosed. The system consists essentially of: (A) a tubular applicator, wherein the applicator comprises: (i) a first chamber and a second chamber; and (ii) a sealable element situated between the first chamber and the second chamber, wherein at least the second chamber is substantially pre-filled with an ocular composition, and (B) a dispenser, wherein the dispenser is bonded to an external surface of a first end of the applicator.

Abstract: A disinfecting conveyor system utilizes ultraviolet light to disinfect a product as it passes through an enclosure on a conveyor. A UV light sensor provides feedback to a control system that can change the amount of UV light exposure, speed of conveyor, and disinfection reaction. A UV light sensor may be a coupled to the conveyor and the UV light intensity and time of exposure within the enclosure may be used to calculate a UV light dose. A user of the system may input a required UV light dose or the type of product to be disinfected and the control system may automatically control the speed of the conveyor and/or the UV light intensity to provide the required UV dose. The system may utilize an air filtration and/or cooling system to provide a flow of clean and cool process air to the enclosure to maintain a temperature that is below a threshold temperature.

Abstract: Systems, methods, and kits useful for cleansing the eyelids and maintaining eyelid hygiene are disclosed. In one embodiment, a system for treating or cleansing an ocular region is disclosed. The system consists essentially of: (A) a tubular applicator, wherein the applicator comprises: (i) a first chamber and a second chamber; and (ii) a sealable element situated between the first chamber and the second chamber, wherein at least the second chamber is substantially pre-filled with an ocular composition, and (B) a dispenser, wherein the dispenser is bonded to an external surface of a first end of the applicator.

Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.

Abstract: An air treatment system includes a particulate filtration portion and a disinfecting portion that may be configured within a single enclosure, such as a conduit. The disinfecting portion may include a UV light source that emits UV light onto the interior surface of the conduit that has a photocatalyst surface. A disinfecting portion may include an X-ray portion, wherein an X-ray emitter is configured within the conduit. In one embodiment, the X-ray emitter is configured to emit X-rays along the conduit and toward a photocatalytic mesh that is also configured within the conduit. The particulate filtration portion may be configured upstream of the disinfection portion.

Abstract: A cooling bed system is configured to provide a cooling airflow around a patient suffering from heat exhaustion, heat stroke and or burns. A cooling bed system produces an airflow over a patient and preferably an airflow from both above and below the patient to more effectively and quickly cool the patient. A cooling bed system may also include a liquid dispenser that creates mist that is carried by the airflow to further cool the patient. A patient may be supported by a platform having a plurality of openings to allow airflow and mist to pass therethrough. A controller controls the airflow rate and/or temperature of the air, and may also control the liquid dispensing rate and/or temperature of the liquid as a function of an input from a temperature sensor to effectively and safely cool the patient.

Abstract: The present disclosure relates to pinion assembly preloading systems and methods of operation. Disclosed are systems including a press actuator that applies an axial force against a pinion assembly; a force sensor that measures a reaction force at the pinion assembly; and a method of controlling the press actuator according to a change in the reaction force.

Abstract: An air treatment system includes a particulate filtration portion and a disinfecting portion that may be configured within a single enclosure, such as a conduit. The disinfecting portion may include a UV light source that emits UV light onto the interior surface of the conduit that has a photocatalyst surface. A disinfecting portion may include an X-ray portion, wherein an X-ray emitter is configured within the conduit. In one embodiment, the X-ray emitter is configured to emit X-rays along the conduit and toward a photocatalytic mesh that is also configured within the conduit. The particulate filtration portion may be configured upstream of the disinfection portion.

Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.

Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.