Patents by Inventor Tsutomu Takeuchi

Tsutomu Takeuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11400682
    Abstract: Provided is a hygroscopic packaging container which eliminates the necessity of filling a moisture absorbent and which has satisfactory working efficiency and is highly effective in moisture absorption. The hygroscopic packaging container is obtained from two gas-barrier multilayer films each comprising a gas-barrier layer and a heat-sealable layer, by stacking the gas-barrier multilayer films so that the surface of one of the heat-sealable layers overlies that of the other and heat-sealing the peripheral parts of the layers, at least one heat-sealable layer of the two gas-barrier multilayer films being a hygroscopic heat-sealable layer.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: August 2, 2022
    Assignee: DAI NIPPON PRINTING CO., LTD.
    Inventors: Naoya Takeuchi, Taeko Kanamori, Tsutomu Noto
  • Publication number: 20220073988
    Abstract: [Problem to be Solved by the Invention] To predict the efficacy of a rheumatoid arthritis therapeutic agent, or find a simple and highly reproducible hiomarker that can be used to assess the activity of disease conditions and states of rheumatoid arthritis, and provide an effective method. [Solution] A method for predicting the efficacy of a rheumatoid arthritis therapeutic agent on a.
    Type: Application
    Filed: December 5, 2019
    Publication date: March 10, 2022
    Inventors: Seiji NAKAMURA, Yumi UEDA, Yohei ISHIZAWA, Madoka HIRAYAMA, Ryo MATOBA, Tsutomu TAKEUCHI, Kunihiro YAMAOKA, Koichi AMANO
  • Publication number: 20210393634
    Abstract: The present invention provides a prophylactic and/or therapeutic agent for inflammatory disease including a compound or a salt thereof, or a solvate thereof, the compound represented by a formula (1): [where each sign is defined as described in the description] as an active ingredient.
    Type: Application
    Filed: May 10, 2019
    Publication date: December 23, 2021
    Applicant: KEIO UNIVERSITY
    Inventors: Tsutomu Takeuchi, Katsuya Suzuki, Keiko Yoshimoto
  • Publication number: 20210215705
    Abstract: An antibody against a peptide having an amino acid sequence AVQGPEETVT QDC (expressed in single letter amino acid code) as represented by SEQ ID: NO. 1 corresponding to the 134- to 146-positions in human BAFF (B cell activating factor belonging to the TNF family) protein which is preferably a monoclonal antibody; a method of producing the above antibody; a medicinal composition containing the antibody; utilization of the antibody; and a method of screening an inhibitory effect or an activating effect on BAFF with the use of the antibody.
    Type: Application
    Filed: March 26, 2021
    Publication date: July 15, 2021
    Applicants: KOWA COMPANY, LTD.
    Inventors: Tsutomu Takeuchi, Keiko Yoshimoto
  • Publication number: 20170336413
    Abstract: A method of evaluating disease activity of rheumatoid arthritis with good sensitivity by a simple method, and a kit for use in the method. It provides a Jacalin-binding O-linked oligosaccharide epitope as a negative marker for diagnosing rheumatoid arthritis, and enables more accurate assessment of disease condition by more objectively determining disease activity of rheumatoid arthritis using the amount of variation of a value obtained by multiplying the amount of MMP-3 in the blood or the amount of bound MMP-3 and ABA, ACA, or ACG in the blood by the reciprocal of the amount of bound MMP-3 and Jacalin in the blood. Through the discovery that an LEL or STL-reactive sugar chain on MMP-3 in the blood is a sugar chain marker for diagnosing polymyalgia rheumatica and relapsing polychondritis, the present invention also provides a method for accurate diagnosis of polymyalgia rheumatica and relapsing polychondritis.
    Type: Application
    Filed: October 29, 2015
    Publication date: November 23, 2017
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITY, GLYCOBIOMARKER LEADING INNOVATION CO. LTD.
    Inventors: Atsushi Kuno, Atsushi Matsuda, Hisashi Narimatsu, Tsutomu Takeuchi, Katsuya Suzuki, Masaru Taskeshita
  • Patent number: 9334004
    Abstract: A vehicle seat structure allowing a reduction in the weight of a seat while ensuring cushioning performance. The seat includes a base plate member with an outer frame forming an outer periphery of the seat, and concave portions with seating positions and a seat back position on an inner peripheral side of the outer frame made concave in a direction of a seating load. In addition, the seat includes a fabric member that is provided in a tensioned state in such a manner so as to close open sides of the concave portions for supporting an occupant's weight. A first cushion member is provided in positions on the fabric member, at least corresponding to the outer frame.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: May 10, 2016
    Assignee: HONDA MOTOR CO., LTD.
    Inventors: Shinji Kawatani, Tsutomu Takeuchi, Yukinori Kurakawa
  • Publication number: 20150045244
    Abstract: The object of the invention is to find a simple biomarker with high reproducibility with regard to a method for evaluating the activity of the condition and progression of rheumatoid arthritis disease and provide an effective evaluation method therefor. The invention is to provide a method for determining the value of a rheumatoid arthritis-linked indicator in a subject, the method being characterized by comprising a step for measuring the amount of expression of the FAM20A gene in blood collected from the subject, a step for analyzing the measured amount of expression using a gene expression profile that is prepared in advance and correlates with the indicator and a step for estimating the value of the indicator in the subject on the basis of the analysis results.
    Type: Application
    Filed: November 17, 2011
    Publication date: February 12, 2015
    Applicants: DNA CHIP RESEARCH INC., SAITAMA MEDICAL UNIVERSITY, KEIO UNIVERSITY
    Inventors: Tsutomu Takeuchi, Koichi Amano, Yohei Ishizawa, Seiji Nakamura, Motohiko Tanino, Yuko Hata
  • Patent number: 8777296
    Abstract: A step unit that guides a sliding door of a vehicle includes a step member and a rail plate member. The step member includes first and second lower rails. The first lower rail has two ends that face toward each other to form a cutout portion in between. The rail plate member is arranged in the cutout portion. The step member includes an insertion hole and an extended portion. The insertion hole is located at a position corresponding to the cutout portion. The extended portion is extended from at least one of the two ends to support the rail plate member against a load received by the rail plate member from the roller. The rail plate member is inserted through the insertion hole from above the upper side of the step member and fixed by a fastening member to the step member.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: July 15, 2014
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Seiichi Suzuki, Tsutomu Takeuchi, Toshihiko Ishida
  • Publication number: 20140024055
    Abstract: An antibody against a peptide having an amino acid sequence AVQGPEETVT QDC (expressed in single letter amino acid code) as represented by SEQ ID: NO. 1 corresponding to the 134- to 146-positions in human BAFF (B cell activating factor belonging to the TNF family) protein which is preferably a monoclonal antibody; a method of producing the above antibody; a medicinal composition containing the antibody; utilization of the antibody; and a method of screening an inhibitory effect or an activating effect on BAFF with the use of the antibody.
    Type: Application
    Filed: October 3, 2013
    Publication date: January 23, 2014
    Applicants: KOWA COMPANY, LTD.
    Inventors: Tsutomu Takeuchi, Keiko Yoshimoto
  • Patent number: 8622408
    Abstract: A step unit comprises: a step member which is provided on the vehicle body side so as to be adjacent to a slide door of the vehicle and has a flat plate section on which an occupant's foot is placed; and a drive device which is affixed to the step member and drives the slide door to open and close the slide door. The step member is molded using a resin material and has a accommodation portion which is provided with a bottom formed below the upper surface of the flat plate section. The drive device is affixed while at least a part thereof is accommodated within the accommodation portion.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: January 7, 2014
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi, Shigeyuki Miyazaki, Shin Sakai, Seiichi Suzuki
  • Publication number: 20130307291
    Abstract: A step unit that guides a sliding door of a vehicle includes a step member and a rail plate member. The step member includes first and second lower rails. The first lower rail has two ends that face toward each other to form a cutout portion in between. The rail plate member is arranged in the cutout portion. The step member includes an insertion hole and an extended portion. The insertion hole is located at a position corresponding to the cutout portion. The extended portion is extended from at least one of the two ends to support the rail plate member against a load received by the rail plate member from the roller. The rail plate member is inserted through the insertion hole from above the upper side of the step member and fixed by a fastening member to the step member.
    Type: Application
    Filed: August 10, 2011
    Publication date: November 21, 2013
    Applicant: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Seiichi Suzuki, Tsutomu Takeuchi, Toshihiko Ishida
  • Patent number: 8561773
    Abstract: A drive device is provided with a housing 11 and an electromagnetic clutch mechanism 14 accommodated in the housing. The electromagnetic clutch mechanism 14 is provided with an armature 41 rotatably supported in the housing 11, a rotor 42 arranged to face the armature 41 and rotatably supported in the housing 11, and a coil 46. An annular magnet 44 is fixed on the outer circumference surface of the rotor 42. A sensor 15 arranged inside the housing 11 detects a polarity change of the magnet 44 in association with rotation of the rotor 42. The magnet 44 is provided with an annular wall portion 44b extending toward the armature 41 beyond a surface on which the armature 41 is in contact with the rotor 42 with respect to the axial direction. The annular wall portion 44b is spaced radially outward from the armature 41. The annular wall portion 44b prevents abrasion powder produced on actuation of the electromagnetic clutch mechanism 14 from being scattered.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: October 22, 2013
    Assignees: Aisin Seiki Kabushiki Kaisha, Ogura Clutch Co., Ltd.
    Inventors: Ryoichi Fukumoto, Tomoaki Nishimura, Tsutomu Takeuchi, Hiroyasu Onai, Takashi Yamaguchi
  • Patent number: 8418827
    Abstract: A driving device includes a first rotating member, an armature member being movable and rotatable together with, a second rotating member being rotatable relative to the armature member, a magnetic force generating portion for generating a magnetic force for attracting the armature member toward the second rotating member in order to establish a connection between the armature member and the second rotating member so as to be integrally rotatable, a sensor magnet fixed to the second rotating member, a sensor provided for detecting a change of the magnetic field and a fixing member formed with a first claw portion engaged with the second rotating member and a second claw portion engaged with the sensor magnet while being press-fitted thereto in a radial direction thereof, wherein the sensor magnet is fixed to the second rotating member by means of the fixing member.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: April 16, 2013
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi, Shigeyuki Miyazaki, Shin Sakai
  • Patent number: 8413379
    Abstract: A step unit includes: a step member which is provided with a pair of lower rails extending in an opening and closing direction of a slide door of the vehicle; and a rail plate member which is provided to a cutout formed in a part of either of the lower rails and which continuously connects the lower rails in the opening and closing direction. The step member is molded using a resin material and is provided with an insertion hole which vertically penetrates through the step member at a position corresponding to the cutout; and a support extension section which is extended from a side end of the cutout of the lower rail. The rail plate member is mounted to the step member by being inserted so as to penetrate through the insertion hole from above the step member.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: April 9, 2013
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi
  • Publication number: 20120261894
    Abstract: A step unit comprises: a step member which is provided on the vehicle body side so as to be adjacent to a slide door of the vehicle and has a flat plate section on which an occupant's foot is placed; and a drive device which is affixed to the step member and drives the slide door to open and close the slide door. The step member is molded using a resin material and has a accommodation portion which is provided with a bottom formed below the upper surface of the flat plate section. The drive device is affixed while at least a part thereof is accommodated within the accommodation portion.
    Type: Application
    Filed: November 17, 2010
    Publication date: October 18, 2012
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi, Shigeyuki Miyazaki, Shin Sakai, Seiichi Suzuki
  • Publication number: 20120222914
    Abstract: A step unit includes: a step member which is provided with a pair of lower rails extending in an opening and closing direction of a slide door of the vehicle; and a rail plate member which is provided to a cutout formed in a part of either of the lower rails and which continuously connects the lower rails in the opening and closing direction. The step member is molded using a resin material and is provided with an insertion hole which vertically penetrates through the step member at a position corresponding to the cutout; and a support extension section which is extended from a side end of the cutout of the lower rail. The rail plate member is mounted to the step member by being inserted so as to penetrate through the insertion hole from above the step member.
    Type: Application
    Filed: November 17, 2010
    Publication date: September 6, 2012
    Applicant: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi
  • Patent number: 8217543
    Abstract: An electromagnetic clutch includes a motor, a worm wheel rotatably driven by a motor, a rotor having an electromagnetic coil and rotatable about a same rotational axis as the worm wheel, an armature that is mounted to the worm wheel and is pulled into contact with the rotor upon application of electric power to the electromagnetic coil, so that the armature is rotated with the rotor, a cover member configured to cover the rotor and the armature, and a power supply mechanism disposed between the cover member and the rotor and connected to a power source for supplying power to the electromagnetic coil.
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: July 10, 2012
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi, Naoya Oku
  • Publication number: 20120126589
    Abstract: A vehicle seat structure allowing a reduction in the weight of a seat while ensuring cushioning performance. The seat includes a base plate member with an outer frame forming an outer periphery of the seat, and concave portions with seating positions and a seat back position on an inner peripheral side of the outer frame made concave in a direction of a seating load. In addition, the seat includes a fabric member that is provided in a tensioned state in such a manner so as to close open sides of the concave portions for supporting an occupant's weight. A first cushion member is provided in positions on the fabric member, at least corresponding to the outer frame.
    Type: Application
    Filed: November 18, 2011
    Publication date: May 24, 2012
    Inventors: Shinji KAWATANI, Tsutomu Takeuchi, Yukinori Kurakawa
  • Publication number: 20110236899
    Abstract: A method for predicting a pharmaceutical efficacy of an anti-TNF? antibody drug against rheumatoid arthritis, the method including measuring an amount of ADAMTS5 contained in a sample derived from a subject, and determining whether or not the anti-TNF? antibody drug is efficient against rheumatoid arthritis by employing the amount of ADAMTS5 as an index.
    Type: Application
    Filed: March 30, 2011
    Publication date: September 29, 2011
    Inventors: KENSEI TSUZAKA, Tsutomu Takeuchi
  • Publication number: 20110227436
    Abstract: An electromagnetic clutch includes a motor, a worm wheel rotatably driven by a motor, a rotor having an electromagnetic coil and rotatable about a same rotational axis as the worm wheel, an armature that is mounted to the worm wheel and is pulled into contact with the rotor upon application of electric power to the electromagnetic coil, so that the armature is rotated with the rotor, a cover member configured to cover the rotor and the armature, and a power supply mechanism disposed between the cover member and the rotor and connected to a power source for supplying power to the electromagnetic coil.
    Type: Application
    Filed: October 15, 2008
    Publication date: September 22, 2011
    Applicant: Aisin Seiki Kabushiki Kaisha
    Inventors: Toshihiko Ishida, Tsutomu Takeuchi, Naoya Oku