Abstract: A one trip cement plugging and milling/drilling sidetrack assembly, including a whipstock having a cement flow bore therethrough, a milling/drilling system having a cement flow bore therethrough attached to the whipstock, and a cement flow adapter conduit connecting the flow bore in the milling/drilling system with the flow bore in the whipstock. A method for cement plugging and milling/drilling a sidetrack in one trip, including flowing cement through a mill/drill, through an adapter conduit and through a whipstock connected to the mill/drill, creating a cement plug with the cement, setting an anchor connected to the whipstock, and drilling a sidetrack. A wellbore system, including a borehole in a subsurface formation, a string in the borehole, and a one trip cement plugging and milling/drilling sidetrack assembly disposed within or as a part of the string.

Abstract: Implementations relate to an automated assistant that provides and manages output from one or more elements of output hardware of a computing device. The automated assistant manages dynamic adjustment of access permissions to the computing device according to, for example, a detected presence of one or more users. An active-user queue can be established each time a unique user enters a viewing window of a camera of the computing device when, up to that point, no user was considered active. Multiple image frames can be captured via the camera and processed to determine whether an initial user remains in the viewing window and/or whether another user has entered the viewing window. The initial user can be considered active as long as they are exclusively detected in the viewing window. Restricted content associated with the user may be rendered by the computing device whilst the user is active.

Abstract: Compositions comprising multiple hydrogel particles having substantially the same diameter, but with each subgrouping of particles from the multiple hydrogel particles having different associated values for one or more passive optical properties that can be deconvoluted using cytometric instrumentation. Each hydrogel particle from the multiple hydrogel particles can be functionalized with a different biochemical or chemical target from a set of targets. A method of preparing hydrogel particles includes forming droplets and polymerizing the droplets, with optional functionalization.

Abstract: Methods, apparatus, systems, and computer-readable media are provided for generating and/or adapting automated assistant content according to a distance of a user relative to an automated assistant interface that renders the automated assistant content. For instance, the automated assistant can provide data for a client device to render. The client device can request additional data when the user relocates closer to, or further from, the client device. In some implementations, a request for additional data can identify a distance between the user and the client device. In this way, the additional data can be generated or selected according to the distance in the request. Other implementations can allow an automated assistant to determine an active user from a group of users in an environment, and determine a distance between the active user and the client device in order that any rendered content can be tailored for the active user.

Abstract: A digital-to-analog converter device including a set of components, each component included in the set of components including a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell is provided by the present disclosure. The digital-to-analog converter device further includes a plurality of switches, each switch included in the plurality of switches being coupled to a component included in the set of components, and an output electrode coupled to the plurality of switches. The digital-to-analog converter device is configured to output an output signal at the output electrode. A first unit cell size associated with a first unit cell included in the set of components is different than a second unit cell size associated with a second unit cell included in the set of components.

Abstract: A method is described. The method includes receiving logs from multiple connector nodes, each of the logs having entries that describe changes made to a file system at its respective one of the connector nodes. The method includes constructing a directed acyclic graph (DAG) from the logs' respective entries, the DAG comprising nodes connected by flows, the nodes describing actions made to directories and files of the file system, wherein, a flow of the flows connects a subset of the nodes that describe actions made to a particular directory or file of the file system. The method includes removing one or more irrelevant nodes from the DAG. The method includes applying actions described by remaining nodes of the DAG to an object storage system having respective objects for directories and files of the file system.

Abstract: Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor, such as a dermal sensor, for sensing an analyte level in a bodily fluid of a subject. An applicator is positioned against a skin surface and a force is applied to the applicator causing at least a portion of a sharp and an in vivo analyte sensor to be positioned in the body of the subject. In particular, disclosed herein are embodiments of applicators designed to prevent premature sharp withdrawal and/or reduce the likelihood of improper sensor insertion. Also disclosed are embodiments of applicators including sharp modules having an angled sharp which can be configured to create an insertion path for a sensor.

Abstract: A method for filtering and removing false targets caused by sidelobes in pulse compression calculates the target filtering threshold to differentiate and eliminate false targets caused by sidelobes in pulse compression. It is applicable in radar signal processing systems using the polyphase P3-coded waveform (the P3 code) for both transmitted and received signals. This method leverages the characteristics of the P3 code's pulse compression output. Specifically, the sidelobes appear symmetrically on both sides of the main lobe, and the distance between the main lobe and the sidelobes is approximately equivalent to the pulse width of the transmitted signal, extending to both sides of the main lobe. For each pulse width of the signal, this distance is fixed and can be predetermined. Experimental results on radar systems have demonstrated that the proposed method effectively filters out all false targets caused by sidelobes in pulse compression.

Abstract: A stent system and method to prevent stent migration. The stent system includes a magnetic stent comprising an outer surface and an inner surface, a proximal end, and a distal end with three or more magnets disposed thereon and configured to form a ring. The system may further have a magnetic ring comprising three or more magnets configured to form a ring. The magnetic ring is disposed proximally or distally to the magnetic stent, which allows magnetic repulsion to maintain the position of the stent.

Abstract: A slip subsystem, including a slip having wickers angled in a first direction and wickers angled in a second direction opposite the first direction, an engager disposed adjacent the slip to selectively engage the wickers, and a biaser to bias the engager into engagement with the wickers. An anchor including a housing having a slip ramp, a drive plate, a power spring to bias the drive plate, a slip subsystem operably connected with the housing. A method for setting an anchor in a borehole, including driving a drive plate into a slip, forcing the slip to climb a housing, engaging an activation block with the slip to prevent slip movement relative to the housing in an anti-setting direction. A borehole system, including a borehole in a subsurface formation, a string in the borehole, and a slip subsystem disposed within or as a part of the string.

Abstract: A slip subsystem, including a slip having wickers angled in a first direction and wickers angled in a second direction opposite the first direction, an engager disposed adjacent the slip to selectively engage the wickers, and a biaser to bias the engager into engagement with the wickers. An anchor including a housing having a slip ramp, a drive plate, a power spring to bias the drive plate, a slip subsystem operably connected with the housing. A method for setting an anchor in a borehole, including driving a drive plate into a slip, forcing the slip to climb a housing, engaging an activation block with the slip to prevent slip movement relative to the housing in an anti-setting direction. A borehole system, including a borehole in a subsurface formation, a string in the borehole, and a slip subsystem disposed within or as a part of the string.

Abstract: The described method may include receiving user input indicating a configuration identifying a large language model (LLM) and a subset of documents indicated in the configuration as being available to a tenant. The method may include generating one or more vectorizations of content of the subset of documents. The method may include receiving a request to generate a generative response. The method may include generating the generative artificial intelligence (AI) prompt using the content to ground the generative AI prompt. The subset of documents may be identified based on a comparison between a vectorization of the request and the one or more vectorizations and based at least in part on a determination that a user associated with the tenant is permitted to access the subset of documents. The method may include presenting a response to the generative AI prompt, the response generated by the LLM using the generative AI prompt.

Abstract: Implementations relate to generating and using multimodal embeddings. In various implementations, first modality data may be obtained and encoded into first modality embedding(s) using a trained first modality encoder that is stored in memory of edge-based client device(s). Second modality data may be obtained and encoded into second modality embedding(s) using a trained second modality encoder that is also stored in the memory of the edge-based client device(s). The first and second modality embeddings may be processed using an edge-based multimodal LLM that is also stored locally in memory of the edge-based client device(s) to generate a multimodal contextual embedding, which may be provided to a remote server that hosts a central LLM, e.g., in conjunction with a natural language input provided by the user. Information generated using the central LLM, responsive to the natural language input, may be received from the remote server.

Abstract: Hydrogel beads with quantifiable attached biomolecules and their use as cell mimics in cytometric applications are described. The cell mimics described herein are selectively tunable to have at least one optical property substantially similar to the at least one optical property of a target cell (e.g., CD34+ stem cell). The disclosure further relates to methods of using the disclosed cell mimics as enrichment controls in cytometric applications.

Abstract: An assembly and method for delivery of an analyte sensor including a reusable applicator having a proximal portion and a distal portion are disclosed. The reusable applicator can include a housing, a sensor carrier configured to releasably receive the first analyte sensor, a sharp carrier configured to releasably receive a sharp module, and an actuator movable relative to the housing.

Abstract: This invention is related to molecules and methods of use of said molecules or compounds comprising said molecules. A molecule may be a pomalidomide or a thalidomide analogue. A method of inducing degradation of a target protein comprising one or more zinc finger polypeptides in a cell may comprise exposing a cell transfected with the target protein with a molecule as described herein, a pharmaceutically acceptable salt thereof, or any combination thereof. A method of inducing degradation of a target protein comprising one or more FK506 binding protein (FKBP) domains or degradation of a target amine in a cell may comprise exposing a cell transfected with the target protein or comprising the target amine with a composition comprising a molecule as described herein, a pharmaceutically acceptable salt thereof, or any combination of compositions comprising molecules as described herein and pharmaceutically acceptable salts thereof. A method may improve on-target effects and reduce off-target effects.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: A method includes calibrating a cytometric device for analysis of a target cell, by inserting, into the cytometric device, a hydrogel particle. The hydrogel particle has at least one of a background fluorescent property or a spectral property that is substantially similar to the at least one of a background fluorescent property or a spectral property of the target cell. The method also includes measuring at least one property of the hydrogel particle using the cytometric device.

Abstract: Methods and compositions for treatment of dry-eye disorders are provided. In particular, the present disclosure provides methods and compositions for modulating WNT (Wingless and lnt-1) signaling in a subject to modulate regeneration of tear-producing acinar cells to treat aqueous-deficient type dry-eye diseases. Further disclosed are WNT signaling modulators used in the methods.