Abstract: A method for filling toner into a toner cartridge includes the steps of (a) taking a container, which accommodates the toner therein and has opposite first and second ends, and then forming a toner outlet at the first end, (b) sleeving the toner cartridge, which is provided at an end thereof with an opening, onto the container from the first end to the second end via the opening, (c) forming an air permeable hole at the second end, (d) withdrawing the container from the toner cartridge to enable the toner to leave the container via the toner outlet and stay inside the toner cartridge, and (e) sealing the opening of the toner cartridge by a cover. The method is simple and convenient to operate. With the method, the toner can be effectively filled without leakage and with reduced amount of residual toner.

Abstract: An extreme ultra violet (EUV) lithography apparatus includes a light source that generates an EUV light beam, a scanner that receives the light from a junction with the light source and directs the light to a reticle stage, and a debris catcher disposed on a EUV beam path between the light source and the scanner. The debris catcher includes a network membrane including a plurality of nano-fibers.

Abstract: This disclosure provides a collagen fiber-based ink for bioprinting comprising a high solid content of collagen fiber particles that are suitable for manufacturing collagen-based scaffolds and tissue equivalent implants for regenerative medicine applications.

Abstract: An optical system is provided, including a fixed assembly, a plurality of movable members, and a plurality of driving assemblies respectively connected to the movable members. The movable members are connected to an optical element and movable relative to the fixed assembly. The driving assemblies respectively drive the movable members to move relative to the fixed assembly in different time intervals.

Abstract: Provided herein are lipid formulations comprising a lipid and a capsid free, non-viral vector (e.g. ceDNA). Lipid particles (e.g., lipid nanoparticles) of the invention include a lipid formulation that can be used to deliver a capsid-free, non-viral DNA vector to a target site of interest (e.g., cell, tissue, organ, and the like).

Abstract: The present invention relates to a glycosaminoglycan impregnated biopolymer-based scaffold implant for repairing and regeneration of damaged and diseased human menisci. The biopolymer can be any suitable natural or genetically engineered biopolymers. This scaffold implant has several advantages over prior art implants including higher biomechanical strength and lower surface friction. A method of making the scaffold implant is also disclosed.

Abstract: A grounding structure includes a flexible conductive webbing and a counterweight disposed on the flexible conductive webbing. The flexible conductive webbing is weaved from conductive wires, provided to be mounted on a carrier and electrically connected to the carrier. The counterweight is used to allow the flexible conductive webbing to contact a ground in a way of surface contact for electrostatic discharge.

Abstract: A method for producing a collagen meniscus implant by obtaining a freshly excised non-human meniscus, rinsing it in an aqueous solution, drying the rinsed meniscus, shaping it to approximate in dimension an average-sized human meniscus, extracting non-collagenous material from the shaped meniscus, and sterilizing it, yielding a collagen meniscus implant containing at least 90% by weight of type I collagen, less than 0.5% by weight of glycosaminoglycan, and less than 600 ppm DNA. Also disclosed is a collagen meniscus implant prepared by the above method. Further provided is a biocompatible and bioresorbable porous implant for meniscus repair. The implant includes a three-dimensional network of collagen fibers oriented in a direction approximating the collagen fiber orientation of a human meniscus. The implant has a size and a contour substantially equivalent to a human meniscus, and has a chemical composition similar to the above-described collagen meniscus implant.

Abstract: An implantable drug-delivery device for repairing a crushed peripheral nerve. The drug-delivery device includes a matrix formed of a biopolymer and an erythropoietin (EPO) entrapped in the matrix. After in vivo implantation of the drug-delivery device, the EPO elutes over a period of 1 day to 12 weeks. Also disclosed is a method for repairing a crushed peripheral nerve using the implantable drug-delivery device.

Abstract: An implantable drug-delivery device for repairing a severed peripheral nerve. The drug-delivery device includes a matrix formed of a biopolymer and an erythropoietin (EPO) entrapped in the matrix. After in vivo implantation of the drug-delivery device, the EPO elutes over a period of 1 day to 12 weeks. Also disclosed is a method for repairing a severed peripheral nerve using the implantable drug-delivery device.

Abstract: An implant for the repair of bone and cartilage that includes a cell conductive zone that contains biopolymeric fibers and an osteoconductive zone that contains biopolymeric fibers and calcium-containing mineral particles. The biopolymeric fibers from one zone overlap with the fibers in the other zone forming a stable physical and mechanical integration of the two zones, thus conferring in vivo stability to the implant.

Abstract: A calibration method of an optical system is provided, wherein the optical system includes a movable element that can move within an operation interval. The calibration method includes the step of establishing a relationship between the operation interval and an electrical signal coding sequence. The calibration method further includes the step of establishing a relationship between the operation interval and a sensing signal coding sequence.

Abstract: A waste toner detection device includes a stirring shaft for stirring waste toners, a transmission member moveable in response to a rotational load of the stirring shaft between an engaged position and a disengaged position where the transmission member does not transmit rotation to the stirring shaft, a rotary arm drivenable by the transmission member when the transmission member is located at the disengaged position, and an indication member. The indication member is restricted by the rotary arm at a retracted position when the rotary arm is located at a locked position, and the indication member is driven by a biasing force to move to an extended position when the rotary arm is located at a released position. As a result, the waste toner detection device can accurately detects whether the amount of the waste toners stored in a waste toner container has reached a predetermined amount.

Abstract: An implant for the repair of bone and cartilage that includes a cell conductive zone that contains biopolymeric fibers and an osteoconductive zone that contains biopolymeric fibers and calcium-containing mineral particles. The biopolymeric fibers from one zone overlap with the fibers in the other zone forming a stable physical and mechanical integration of the two zones, thus conferring in vivo stability to the implant.

Abstract: A compression and kink resistant tubular implant for nerve repair. The implant includes a tubular biopolymeric membrane and a polymeric supporting filament. Also provided is a shaped compression resistant implant for ridge augmentation in dental surgery. Methods for producing the implants are also provided.

Abstract: An optical system is provided, including a fixed assembly, a plurality of movable members, and a plurality of driving assemblies respectively connected to the movable members. The movable members are connected to an optical element and movable relative to the fixed assembly. The driving assemblies respectively drive the movable members to move relative to the fixed assembly in different time intervals.

Abstract: A calibration method of an optical system is provided, wherein the optical system includes a movable element that can move within an operation interval. The calibration method includes the step of establishing a relationship between the operation interval and an electrical signal coding sequence. The calibration method further includes the step of establishing a relationship between the operation interval and a sensing signal coding sequence.

Abstract: A toner detection device of a waste toner container having a housing includes a rotational wheel, a transmission member and a resilient member. The rotational wheel is rotatably disposed to the housing and provided with a first abutment portion. The transmission member including a second abutment position is connected with the rotational wheel in a way that the transmission member is rotatable with the rotational wheel and moveable relative to the rotational wheel between a first position and a second position. Two ends of the resilient member are respectively abutted against the first and second abutment portions in a way that the second abutment portion approaches the first abutment portion and the transmission member is rotatable relative to the rotational wheel with the transmission member moving from the first position to the second position.

Abstract: A method for producing a collagen meniscus implant by obtaining a freshly excised non-human meniscus, rinsing it in an aqueous solution, drying the rinsed meniscus, shaping it to approximate in dimension an average-sized human meniscus, extracting non-collagenous material from the shaped meniscus, cross-linking, and sterilizing it, yielding a collagen meniscus implant containing at least 90% by weight of type I collagen, less than 0.5% by weight of native glycosaminoglycan, and less than 600 ppm DNA. Also disclosed is a collagen meniscus implant prepared by the above method. Further provided is a biocompatible and bioresorbable porous implant for meniscus repair. The implant includes a three-dimensional network of collagen fibers oriented in a direction approximating the collagen fiber orientation of a human meniscus. The implant has a size and a contour substantially equivalent to a human meniscus, and has a chemical composition similar to the above-described collagen meniscus implant.

Abstract: A density gradient biopolymeric matrix implant is disclosed. The implant includes a first homogeneous matrix layer and a second homogeneous matrix layer having a density different from that of the first homogeneous matrix layer. Biopolymeric fibers at the surface of the first homogeneous matrix layer are physically in contact with and cross-linked to the biopolymeric fibers at the surface of the second homogeneous matrix layer. Also disclosed is a three-dimensional density gradient biopolymeric matrix implant that includes a first homogeneous matrix surrounding a second homogeneous matrix having a different density. Biopolymeric fibers at an inner surface of the first homogeneous matrix are physically in contact with and cross-linked to biopolymeric fibers at an outer surface of the second homogeneous matrix. Furthermore, methods for preparing the density gradient biopolymeric matrix implant and the three-dimensional density gradient biopolymeric matrix implant are provided.