Patents by Inventor Udi Eyal Fima

Udi Eyal Fima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long-acting veterinary polypeptides and methods of producing and administering same
    Patent number: 8465948
    Abstract: A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: June 18, 2013
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting growth hormone and methods of producing same
    Patent number: 8450269
    Abstract: Use of a growth hormone protein and polynucleotides encoding same comprising an amino-terminal carboxy-terminal peptide (CTP) of chorionic gonadotrophin and two carboxy-terminal chorionic gonadotrophin CTPs attached to the growth hormone in methods of inducing growth or weight gain, method of increasing insulin-like growth factor (IGF-1) levels, and methods of reducing the dosing frequency of a growth hormone in a human subject are disclosed. Pharmaceutical compositions comprising the growth hormone and polynucleotides encoding the growth hormone of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: May 28, 2013
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting polypeptides and methods of producing same
    Patent number: 8426166
    Abstract: A polypeptide and polynucleotides encoding same comprising one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to an amino terminus of a cytokine and two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a cytokine are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: April 23, 2013
    Assignee: Prolor Biotech Inc.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting interferons and derivatives thereof and methods thereof
    Patent number: 8323636
    Abstract: A polypeptide and polynucleotides encoding same comprising carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an IFN protein are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: December 4, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting growth hormone and methods of producing same
    Patent number: 8304386
    Abstract: A polypeptide and polynucleotides encoding same comprising one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to an amino terminus of a growth hormone and two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a growth hormone are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: November 6, 2012
    Assignee: Prolor Biotech, Inc.
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME
    Publication number: 20120208759
    Abstract: Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed.
    Type: Application
    Filed: February 14, 2012
    Publication date: August 16, 2012
    Inventors: Udi Eyal Fima, Gili Hart
  • Long-acting veterinary polypeptides and methods of producing and administering same
    Patent number: 8114836
    Abstract: A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: February 14, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME
    Publication number: 20120035101
    Abstract: Use of a growth hormone protein and polynucleotides encoding same comprising an amino-terminal carboxy-terminal peptide (CTP) of chorionic gonadotrophin and two carboxy-terminal chorionic gonadotrophin CTPs attached to the growth hormone in methods of inducing growth or weight gain, method of increasing insulin-like growth factor (IGF-1) levels, and methods of reducing the dosing frequency of a growth hormone in a human subject are disclosed. Pharmaceutical compositions comprising the growth hormone and polynucleotides encoding the growth hormone of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: August 2, 2011
    Publication date: February 9, 2012
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting EPO polypeptides and derivatives thereof and methods thereof
    Patent number: 8110376
    Abstract: A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an EPO peptide are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: February 7, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME
    Publication number: 20120015437
    Abstract: A polypeptide and polynucleotides encoding same comprising one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to an amino terminus of a cytokine and two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a cytokine are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: July 27, 2011
    Publication date: January 19, 2012
    Inventors: Fuad Fares, Udi Eyal Fima
  • Polynucleotides encoding long-acting growth hormone polypeptides and methods of producing same
    Patent number: 8097435
    Abstract: A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a peptide-of-interest are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: January 17, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING VETERINARY POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME
    Publication number: 20120004286
    Abstract: A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
    Type: Application
    Filed: July 28, 2011
    Publication date: January 5, 2012
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING INTERFERONS AND DERIVATIVES THEREOF AND METHODS THEREOF
    Publication number: 20110286967
    Abstract: A polypeptide and polynucleotides encoding same comprising carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an IFN protein are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: July 28, 2011
    Publication date: November 24, 2011
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting interferons and derivatives thereof and methods thereof
    Patent number: 8048848
    Abstract: A polypeptide and polynucleotides encoding same comprising carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an IFN protein are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: November 1, 2011
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting polypeptides and methods of producing same
    Patent number: 8048849
    Abstract: A polypeptide and polynucleotides encoding same comprising one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to an amino terminus of a cytokine and two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a cytokine are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: November 1, 2011
    Assignee: Modigene, Inc.
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME
    Publication number: 20100317585
    Abstract: Polypeptides and polynucleotides encoding same comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a coagulation factor and not to an amino terminus are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: June 30, 2010
    Publication date: December 16, 2010
    Inventors: Udi Eyal Fima, Gili Hart
  • LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME
    Publication number: 20100081614
    Abstract: A polypeptide and polynucleotides encoding same comprising one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to an amino terminus of a growth hormone and two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a growth hormone are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: July 24, 2009
    Publication date: April 1, 2010
    Inventors: Fuad Fares, Udi Eyal Fima
  • LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME
    Publication number: 20090312254
    Abstract: A polypeptide and polynucleotides encoding same comprising one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to an amino terminus of a cytokine and two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a cytokine are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 17, 2009
    Inventors: Fuad FARES, Udi Eyal Fima
  • LONG-ACTING VETERINARY POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME
    Publication number: 20090286733
    Abstract: A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
    Type: Application
    Filed: March 11, 2009
    Publication date: November 19, 2009
    Inventors: FUAD FARES, UDI EYAL FIMA
  • LONG-ACTING EPO POLYPEPTIDES AND DERIVATIVES THEREOF AND METHODS THEREOF
    Publication number: 20090275084
    Abstract: A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an EPO peptide are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Application
    Filed: March 11, 2009
    Publication date: November 5, 2009
    Inventors: FUAD FARES, UDI EYAL FIMA