Abstract: The invention relates to a grid element for an inhaler which can be arranged in an air duct between a mouthpiece and a capsule chamber of the inhaler, it being possible for turbulence to be generated by means of the grid element in an airflow passing through the air duct. The grid element is characterized in that it comprises a preferably planar grid-type portion having a grid front side which points towards the capsule chamber and a grid rear side, at least one protruding element being arranged on the grid front side, by means of which a capsule that can be arranged in the capsule chamber can be loosely supported.

Abstract: An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device (1) is proposed.

Abstract: An assembly for a drug delivery device (1), and a drug delivery device, are proposed with a housing (13) having proximal and distal ends. A dose member (23) is displaceable proximally with respect to the housing for setting of a dose of a drug. A clutch member (28) is displaceable proximally with respect to the housing when setting the dose. A stop member (30) is configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, The clutch member, when in the clutch stop position, is prevented from further displacement proximally with respect to the housing, and the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member proximally with respect to the housing during setting of the dose.

Abstract: An assembly for a drug delivery device, and a drug delivery device, are proposed with a housing having proximal and distal ends. A dose member is displaceable proximally with respect to the housing for setting of a dose of a drug. A clutch member is displaceable proximally with respect to the housing when setting the dose. A stop member is configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, the clutch member, when in the clutch stop position, is prevented from further displacement proximally with respect to the housing, and the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member proximally with respect to the housing during setting of the dose.

Abstract: A device for providing a medicament from capsules, where the device is integrated into an inhaler and comprises a capsule receiver comprising a capsule chamber, which extends along a first direction (X) in the manner of a tube and in which a capsule can be arranged, and a puncture device for opening the capsules, where the puncture device is arranged in a second direction (Y) radial to the capsule chamber, the puncture device having at least one needle which is moveable in sections into the capsule chamber in the second direction (Y) by means of an actuating button. A respective rear portion of the at least one needle of the puncture device is received in part in a needle receiver. The capsule receiver comprises at least one guide channel extending along the second direction (Y), wherein the needle receiver is arranged in the guide channel in such a moveable manner.

Abstract: The invention relates to a grid element for an inhaler which can be arranged in an air duct between a mouthpiece and a capsule chamber of the inhaler, it being possible for turbulence to be generated by means of the grid element in an airflow passing through the air duct. The grid element is characterised in that it comprises a preferably planar grid-type portion having a grid front side which points towards the capsule chamber and a grid rear side, at least one protruding element being arranged on the grid front side, by means of which a capsule that can be arranged in the capsule chamber can be loosely supported.

Abstract: An assembly for a drug delivery device comprising a housing, a dose member which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose.

Abstract: An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device (1) is proposed.

Abstract: An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device (1) is proposed.

Abstract: A method of preventing setting a dose which exceeds an amount of medication contained in a medication receptacle of a medication delivery device. The device comprising a piston rod comprising a second stop element, a drive device for moving the piston rod, and a dose setting member for setting a dose. The method comprising the steps of moving a dose limiting member which comprises a first stop element axially with respect to the piston rod during dose setting, and utilizing the first and second stop elements to stop an axial movement of the dose limiting member in the proximal direction when the first and second stop elements catch, limiting a movement of the dose setting member for increasing a set dose of medication. The dose limiting member and the piston rod only interact directly, when the first and second stop elements catch.

Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.

Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.

Abstract: An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device (1) is proposed.

Abstract: A substrate for forming cultures of organic cells, comprising the following a spatial body, the cross section of the body comprises a plurality of at least first pores, wherein the pre size of a majority thereof is =1000 ?m, preferably 10-500 ?m, more preferably 10-200 ?m, most preferably 10-100 ?m t; the first pores are fluidically connected to each other: at least the first pores whose pore size is in the region of 500 ?m have a cell-growth promoting property and at least one part of the first pores arranged close to at least one free surface of the body are open towards the outer environment. Preferably, the substrate is an open-pored foam material body made of a synthetic material. The substrate enables spatial cell cultures to be formed.

Abstract: A blood sampling device includes a lancet having a skin piercing member disposed at an end thereof. The lancet is slidable within and releasably engaged with an elongated lancet guide that remains stationary with use of the device. A shell is axially movable relative to the lancet guide between a rest position and an actuate position, with the lancet being spring loaded within the lancet guide by movement of the shell from the rest position to the actuate position.

Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.

Abstract: Modifications of an inhaler and method of use thereof are described. In some embodiments, an inhaler may include one or more systems and/or methods that function to inhibit a child from accessing medicant from an inhaler. A system may function to inhibit a child from accessing an opening of an inhaler from which medicants are dispensed. In some embodiments, a system may inhibit a child from removing a cap for an inhaler. A system may function to inhibit a child from actuating an activation mechanism for an inhaler. A system may function to inhibit a user and/or a child from accidentally actuating an activation mechanism for an inhaler multiple times possibly resulting in an overdose. A system may function to inhibit an activation mechanism for an inhaler from actuating after the activation mechanism has been actuated a predetermined number of times. An inhaler may include a security fitting which functions to permanently plug an inhaler once a prescribed user is finished with the inhaler.

Abstract: Method for producing a cell sensor system for the definition of quality criteria during the production of materials, characterised by the following method steps: a) cultivation of first cells of a specific type under standardised culture conditions (control group), b) cultivation of second cells of the specific type on/in/between different materials to be tested (test group), c) harvesting of the cells, d) determination of the gene activities of the cells of the control group and of the cells of the test group, e) comparison of the gene activities of the test group with the control group, f) identification of the genes for which there is a difference in the gene activities between the control group and the test group, g) construction of a microarray using the identified genes with different gene activity as the gene profile, this created microarray being defined as the standard for the specific cell type, and h) provision of third cells of the specific cell type as cell sensor.

Abstract: A substrate for forming cultures of organic cells, comprising the following a spatial body—the cross section of the body comprises a plurality of at least first pores. wherein the pre size of a majority thereof is =1000 ?m, preferably 10-500 ?m. more preferably 10-200 ?m, most preferably 10-100 ?m t—the first pores are fluidically connected to each other—at least the first pores whose pore size is in the region of 500 ?m have a cell-growth promoting property and at least one part of the first pores arranged close to at least one free surface of the body are open towards the outer environment. Preferably, the substrate is an open-pored foam material body made of a synthetic material.

Abstract: A blood sampling device includes a lancet having a skin piercing member disposed at an end thereof. The lancet is slidable within and releasably engaged with an elongated lancet guide that remains stationary with use of the device. A shell is axially movable relative to the lancet guide between a rest position and an actuate position, with the lancet being spring loaded within the lancet guide by movement of the shell from the rest position to the actuate position.