Patents by Inventor Ulrich Niewohner

Ulrich Niewohner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclically substituted imidazotriazines
    Publication number: 20060166992
    Abstract: The invention relates to new heterocyclically substituted imidazotriazines, processes for their preparation and their use for the production of medicaments for the treatment and/or prophylaxis of cancer and neurodegenerative disorders, in particular of Parkinson's disease and of schizophrenia.
    Type: Application
    Filed: June 25, 2003
    Publication date: July 27, 2006
    Applicant: Bayer Healthcare A G
    Inventors: Martin Hendrix, David Bruckner, Arno Friedl, Irene Gerlach, Volker Hinz, Jorg Keldenich, Frank Mauler, Ulrich Niewohner, Maria Niewohner, Dagmar Karthaus, Karl-Heinz Schlemmer, Adrian Tersteeger, Ozkan Yalkinoglu
  • Substituted imidazotriazines
    Publication number: 20060166993
    Abstract: The invention relates to new substituted imidazotriazines, processes for their preparation and their use for the production of medicaments for the treatment and/or prophylaxis of cancer and neurodegenerative disorders, in particular of Parkinson's disease and of schizophrenia.
    Type: Application
    Filed: June 25, 2003
    Publication date: July 27, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Martin Hendrix, David Bruckner, Arno Friedl, Irene Gerlach, Volker Hinz, Jorg Keldenich, Frank Mauler, Ulrich Niewohner, Maria Niewohner, Dagmar Karthaus, Karl-Heinz Schlemmer, Adrian Tersteegen, Ozkan Yalkinoglu
  • 2-Alkoxyphenyl substituted imidazotriazinones
    Publication number: 20060160810
    Abstract: The 2-phenyl-substituted imidazotriazinones having short unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolising phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for treating cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for treating erectile dysfunction.
    Type: Application
    Filed: February 4, 2002
    Publication date: July 20, 2006
    Inventors: Ulrich Niewohner, Maria Niewohner, Helmut Haning, Martin Radtke, Dietrich Seidel, Erwin Bischoff, Wolfgang Karl
  • Medicaments against viral diseases
    Patent number: 7074784
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: July 11, 2006
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Maria Niewohner, legal representative, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres, Ulrich Niewohner, deceased
  • 5-ethylimidarotriazones
    Patent number: 7074790
    Abstract: The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Grant
    Filed: May 5, 2003
    Date of Patent: July 11, 2006
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary F. Fitzgerald, Graham Sturton, Maria Theresia Niewöhner, legal representative, Ulrich Niewöhner, deceased
  • Selective PDE 2 inhibitors as pharmaceuticals for improving perception
    Patent number: 7022709
    Abstract: The invention relates to the use of selective phosphodiesterase 2 (PDE 2) inhibitors for producing pharmaceuticals for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: April 4, 2006
    Inventors: Frank-Gerhard Böss, Martin Hendrix, Gerhard König, Ulrich Niewöhner, Karl-Heinz Schlemmer, Rudy Schreiber, Franz-Josef Van Der Staay, Dagmar Schauss
  • 5-ethylimidarotriazones
    Publication number: 20060040942
    Abstract: The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: May 5, 2003
    Publication date: February 23, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Ulrich Niewohner, Maria Niewohner
  • 7-Aminoimidazotriazones
    Publication number: 20060040941
    Abstract: The invention relates to novel 7-amino-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: April 22, 2003
    Publication date: February 23, 2006
    Applicant: Bayer HealthCare AG
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Ulrich Niewohner, Maria Niewohner
  • Substituted imidazotriazinones
    Patent number: 6998402
    Abstract: The invention relates to novel substituted imidazotriazinones, to a method for their production and to the use thereof for producing medicaments, in particular to improve perception, powers of concentration, learning capacity and/or memory retentiveness.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: February 14, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Theresia Niewöhner, legal representative, Dagmar Schauss, Gerhard König, Martin Hendrix, Frank-Gerhard Böss, Franz-Josef van der Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Toshiya Moriwaki, Ulrich Niewöhner, deceased
  • 5-ethyl-imidazo (5,1-F) (1,2,4,) triazin-4 (3h)-ones as phosphodiesterase inhibitors
    Publication number: 20050272732
    Abstract: The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: April 22, 2003
    Publication date: December 8, 2005
    Applicant: Bayer Healthcare AG
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Ulrich Niewohner, Maria Niewohner
  • Novel imidazotriazinones and the use thereof
    Publication number: 20050267112
    Abstract: Novel imidazotriazinones of general formula a method for the production and the pharmaceutical use thereof are disclosed.
    Type: Application
    Filed: January 5, 2005
    Publication date: December 1, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewohner, Mazen Es-Sayed, Thomas Lampe, Helmut Haning, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn, Maria Niewohner
  • Use of 2-alkoxyphenyl-substituted imidazotriazinones
    Publication number: 20050234022
    Abstract: The present invention relates to the use of known 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position and cGMP PDE-inhibitory properties for the production of medicaments for the treatment of cardiac insufficiency, psoriasis, female infertility, cancer, diabetes, ophthalmic disorders such as glaucoma, disorders of gastric motility, cystic fibrosis, premature labour, pulmonary hypertension, bladder disorders, prostate hyperplasia, nitrate-induced tolerance, pre-eclampsia, alopecia, Parkinson's disease, pain, tinnitus or the renal syndrome.
    Type: Application
    Filed: June 17, 2005
    Publication date: October 20, 2005
    Applicant: Bayer HealthCare AG
    Inventors: Ulrich Niewohner, Maria Niewohner, Erwin Bischoff, Helmut Haning, Afssaneh Rahbar, Tiemo-Joerg Bandel, Wolfgang Barth
  • 7-Alkyl and cycloalkyl-substituted imidazotriazinones
    Patent number: 6943163
    Abstract: The present invention relates to 7-alkyl- and cycloalkyl-substituted imidazotriazinones, to processes for their preparation and to their use as medicaments, in particular as inhibitors of cGMP-metabolizing phosphodiesterases.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: September 13, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn
  • Imidazotriazines for use as phosphodiesterase inhibitors
    Patent number: 6936609
    Abstract: The invention relates to new imidazotriazines, processes for their preparation, and their use for the production of medicaments for the treatment and/or prophylaxis of neurodegenerative disorders, in particular Parkinson's disease.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: August 30, 2005
    Assignee: Bayer HealthCare AG
    Inventors: Jens-Kerim Ergüden, Marcus Bauser, Nils Burkhardt, Dietmar Flubacher, Arno Friedl, Irene Gerlach, Volker Hinz, Reinhard Jork, Paul Naab, Maria Theresia Niewöhner, Thorsten Oliver Repp, Karl-Heinz Schlemmer, Jürgen Stoltefuss, David Brückner, Martin Hendrix, Dagmar Schauss, Adrian Tersteegen, Ulrich Niewöhner
  • Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
    Patent number: 6930114
    Abstract: The present invention relates to pyrrolo[2.1-a]dihydroisoquinolines which are inhibitors of phosphodiesterase 10a and can be used for combating cancer.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: August 16, 2005
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Maria Theresia Niewöhner, Marcus Bauser, Jens-Kerim Ergüden, Dietmar Flubacher, Paul Naab, Thorsten-Oliver Repp, Jürgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese, Ulrich Niewöhner
  • Use of 2-alkoxyphenol-substituted imidazotriazinones
    Patent number: 6930108
    Abstract: The present invention relates to the use of known 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position and cGMP PDE-inhibitory properties for the production of medicaments for the treatment of cardiac insufficiency, psoriasis, female infertility, cancer, diabetes, ophthalmic disorders such as glaucoma, disorders of gastric motility, cystic fibrosis, premature labour, pulmonary hypertension, bladder disorders, prostate hyperplasia, nitrate-induced tolerance, pre-eclampsia, alopecia, Parkinson's disease, pain, tinnitus or the renal syndrome.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: August 16, 2005
    Assignee: Bayer HealthCare AG
    Inventors: Maria Theresia Niewöhner, Erwin Bischoff, Helmut Haning, Afssaneh Rahbar, Tiemo-Joerg Bandel, Wolfgang Barth, Ulrich Niewöhner
  • 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Patent number: 6890922
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: May 10, 2005
    Assignee: Bayer Healthcare AG
    Inventors: Maria Niewohner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski, Ulrich Niewöhner
  • Triazolotriazinones and the use thereof
    Publication number: 20050096320
    Abstract: The invention relates to novel triazolotriazinones of the general formula and to a method for their production and pharmaceutical use thereof.
    Type: Application
    Filed: December 4, 2003
    Publication date: May 5, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Ulrich Niewohner, Helmut Haning, Thomas Lampe, Mazen Es-Sayed, Gunter Schmidt, Erwin Bischoff, Klaus Dembowsby, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Imidazotriazinones and the use thereof
    Patent number: 6878708
    Abstract: Novel imidazotriazinones of general formula (I), a method for the production and the pharmaceutical use thereof are disclosed.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: April 12, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Niewöhner, Mazen Es-Sayed, Thomas Lampe, Helmut Haning, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn, Ulrich Niewöhner
  • 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Publication number: 20050070541
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Application
    Filed: August 20, 2004
    Publication date: March 31, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewohner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jorg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski