Abstract: The invention relates to antibodies against VASP (vasodilator-stimulated phosphoprotein) which only bind VASP as an antigen when VASP is present in phosphorylated form, to hybridoma cells for their preparation, and to the use of the antibodies or antibody fragments as diagnostic agents and/or therapeutic agents.

Abstract: This invention relates to polyurethane compositions which cross-link via a silane polycondensation and contain at least one alkoxysilane-functional polyurethane, at least one basic filler, at least one reaction product of an aminosilane with a maleic or fumaric ester, at least one organometallic compound and optionally additional auxiliary substances, to a process for their preparation, and to their use.

Abstract: The invention relates to antibodies against VASP (vasodilator-stimulated phosphoprotein) which only bind VASP as an antigen when VASP is present in phosphorylated form, to hybridoma cells for their preparation, and to the use of the antibodies or antibody fragments as diagnostic agents and/or therapeutic agents.

Abstract: The invention relates to polyurethane materials, cross-linked by silane polycondensation, containing alkoxylsilane functional polyurethanes, alkaline fillers, phosphorous compounds aminosilanes, organometallic compounds and optionally additional auxiliary agents, to a method for their production and to the use thereof.

Abstract: The invention relates to an HTS-appropriate test system for detecting the activity of cyclo-nucleotide-dependent protein kinases (cNPK) containing: a) at least one test compound; b) at least one appropriate cNPK substrate; c) at least one composition, which is to be incubated and which contains cNPK and ATP, optionally, phosphorylation reaction stoppers, and; d) an appropriate detection system for quantifying the phosphorylation of the cNPK substrate. The invention also relates to an HTS-appropriate test system for detecting the activity of VASP phosphatases containing: e) at least one test compound; f) at least one appropriate VASP phosphatase substrate; g) at least one composition, which is to be incubated and which contains VASP phosphatase, and; h) an appropriate detection system for quantifying the dephosphorylation of the VASP phosphatase substrate.

Abstract: The present invention relates to new alkoxysilane-functional piperazinone derivatives, a process for their production, as well as their use as additives in sealants, adhesives, lacquers or coating agents.

Abstract: At least one machine tool, preferably two machine tools (1, 2) is or are provided for the production of workpieces, or for the complete production of complex workparts, which machine tools each have a basic body (3, 4) and machine units (7, 8) movable in the horizontal direction thereon. Each machine unit has a work spindle (13, 14) which is supported displaceably in the axial direction of the spindle in a carrier (11, 12) of crankshaft-like design. The carrier is mounted pivotably and supports each work spindle above a respective transport system (31, 32) for a workpiece or the workparts (37, 38). Machining devices, for example in the form of a tool carrier (44) for turning, drilling and/or milling tools, a laser-welding device (46), a grinding device (47) and a brushing device (48), and also an apparatus for joining, are provided in the functional area of one of these machine tools.

Abstract: The invention relates to a process for preparing nondusting free-flowing pigment concentrates with removal of the water from pigment suspensions comprising polymers and dispersants in a fluidized bed drier. The resulting bead-form pigment concentrates are nondusting and readily free-flowing The invention further embraces the use of pigment concentrates prepared in this way for coloring plastics and polymers.

Abstract: The invention relates to processes for identifying chemical compounds which are capable of modulating the interaction between VASP and zyxin. VASP or a VASP derivative and zyxin or a zyxin derivative which interact with one another are brought into contact with a chemical compound to be examined. The effect on the interaction can be determined using antibodies against VASP or a VASP derivative and/or zyxin or a zyxin derivative, or with the aid of fluorescent labels on VASP or a VASP derivative and zyxin or a zyxin derivative.

Abstract: The invention relates to a procedure for determining an identification of a sample of material, or its properties. Electromagnetic radiation from a radiation source (1) is reflected or transmitted through the sample. The radiation from the sample is collected and analyzed over several channels (7, 7', 7"), which modulate the radiation with a spectral transmission function which is unique for each channel. The modulated radiation is transmitted to one or several detectors (9, 9', 9") which produce output signals which are further electronically processed. The spectral range of each of the individual channels is common to all of the channels. Within the common range the channels are provided with different spectral transmission functions (7, 7',7") which are optimally chosen for a given application.

Abstract: New derivatives of S.sub.P - and R.sub.P -configures cyclic guanosine-3',5'-phosphorothioates and their physiologically and pharmaceutically acceptable salts according to the general formula ##STR1## are cell membrane permeable inhibitors (R.sub.P -isomers) and stimulators (S.sub.P -isomers) of cyclic GMP-dependent protein kinase which are resistant against phosphodiesterase degradation and suitable as ligands for affinity chromatography of cyclic nucleotide-dependent binding proteins.

Abstract: Isocyanate prepolymers having an NCO content of 1.5 to 5.0 wt. % and a monomeric diisocyanate content of less than 0.5 wt. % which are the reaction products ofA) aromatic or cycloaliphatic diisocyanates withB) mixtures ofB1) polyether polyols having a molecular weight of 1000 to 3000 andB2) polyester carbonate diols having a molecular weight of 700 to 3000,wherein components B1) and B2) are present in a weight ratio of 0.25:1 to 1.5:1;a process for the preparation of these isocyanate prepolymers by reacting the preceding starting materials at an NCO/OH equivalent ratio of at least 1.5:1 and optionally with subsequent removing unreacted monomeric diisocyanate by distillation; and the use of these isocyanate prepolymers as binders for sealing or coating compositions.

Abstract: Two-component polyurethane coating compositions essentially containing A) a polyisocyanate component containing A1) certain aliphatic polyisocyanates and A2) certain aromatic polyisocyanates, B) a polyol component containing B1) selected polycaprolactone polyols and/or selected polyether polyols, and optionally B2) other organic polyhydroxyl compounds, and C) known additives used in surface coating technology; and the application of such coating compositions for the manufacture of floor sealers or thin coatings.

Abstract: A nozzle for spraying liquids is provided, especially high viscosity liquid media used in the food and chemical industries. The nozzle finds particular use in fluidized bed spray granulators. A fine spray of high viscosity liquid media is attained. A nozzle head is arranged inside a nozzle housing. The nozzle head has a cylindrical portion terminating in a truncated, cone-shaped portion. A plurality of first flow ducts are arranged like the threads on a screw along the surface of the cylindrical portion for guiding a pressure medium such as air. A plurality of second ducts are arranged between the cylindrical portion and truncated, cone-shaped portion of the nozzle head and supply high viscosity liquid medium to the pressure medium exiting the downstream ends of the plurality of first ducts.

Abstract: A procedure for the production of granulated food, applicable especially to the production of granulated baby and infant food, such as infant food most analogously resembling mother's milk is disclosed. The process provides a new composition of matter consisting of a stable, well dosable, granulated food product, of defined formula, which after reconstitution does not cream up, and which, in the case of the closest approach to the composition of mother's milk, will inhibit intestinal putrefaction. In the process, selected pulverized components are fed into a fluidized bed granulator and remaining fluidized components are sprayed simultaneously, successively or in mixtures, at a product temperature of 30.degree. to 80.degree. C. whereby granulates are obtained. The granulates are dried in the fluidized bed and cooled with air.

Abstract: Press for producing pellets from bulk material with an annular perforated die rotatable about its axis and with a non-rotatable holder, arranged coaxially therein, of press rollers which virtually touch the die with their circumference, while a wheel which is attached to the shaft of the die exhibits on its circumference projections which can be engaged in each case by a hydraulically slidable ram mounted in the housing of the press and movable counter to a spring force.

Abstract: Thermistors (NTC) containing a mixture of terbium oxide and a material selected from the group consisting of samarium and ytterbium oxide are useful in high temperature environments.