Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.

Abstract: The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. In a particular embodiment, the antibodies are capable of binding to ErbB3 and inhibiting ligand mediated phosphorylation of the receptor.

Abstract: The present invention provides a novel class of antibodies and antigen binding fragments thereof that bind the extracellular domain of ErbB3 receptor and inhibit various ErbB3 functions. For example, the antibodies and antigen binding fragments described herein are capable of binding to the receptor designated ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor. Such antibodies and antigen binding fragments thereof have the useful characteristic of inhibiting the proliferation of cancer cells expressing ErbB3.

Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the drive sleeve is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.

Abstract: The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor.

Abstract: The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor.

Abstract: The present invention concerns a prefilled injection device having a container and a dose setting mechanism encapsulated inside the housing. The housing is made from two parts which are locked together by a bayonet coupling: In addition to the bayonet coupling, the two parts are also provided with irreversible locking means locking the two parts permanently together.

Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.

Abstract: An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating.

Abstract: An injection device (1) with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver (70) is allowed to rotate relatively to the piston rod (60), which is blocked from rotation by the clicker element (80). In the second position, the drive sleeve (70) and the injection button is axially movable while the piston rod (60) is allowed to rotate.

Abstract: A compression assembly for distributing an external compression force to a solid oxide fuel cell stack, the compression assembly comprising a force distributing plate, and a force distributing layer so that when said compression assembly is mounted together with the solid oxide fuel cell stack, the external compression force is exerted on the force distributing plate and the force distributing layer is provided next to a surface of at least one end plate, opposite to the surface facing the solid oxide fuel cells. The force distributing layer has a rigid frame extending next to a region of a sealing area of the solid oxide fuel cell stack.

Abstract: The invention provides an interconnect device for a fuel cell comprising an electrolyte, an anode and a cathode, the interconnect device comprising a channel system having a plurality of channels, each channel being closed in one end and having either an inlet side or an outlet side at the open end of the channel, each channel having an inlet side placed in alternating order with a channel having an outlet side, the inlet side of each channel placed in consecutive order on one side of the interconnect, and the outlet sides of each channel placed in consecutive order on the opposite side of the interconnect relative to the inlet side, and a second layer of channels is located on the surface of the channel system. The invention also provides a fuel cell and a fuel cell stack in which the interconnect device is used.

Abstract: This invention provides methods of identifying ligands that are internalized into a cell. The methods typically involve i) contacting the cell with a reporter non-covalently coupled to a ligand; ii) dissociating the reporter from the ligand and removing dissociated reporter from the surface of the cell; and iii) detecting the reporter within said cell (if any is present) where the presence of the reporter within said cell indicates that the ligand binds to an internalizing receptor and is internalized.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: A connector element for making a connection between electrical conductors in a network. The connector element has a front, a rear and a length between the front and the rear. The connector element includes a plurality of contact terminals arranged in at least one plane at the front of the connector element. The plurality of contact terminals are configured for connection with corresponding contact terminals of a mating connector element. The connector element includes a plurality of wire connector terminals arranged in first and second rows at substantially the rear of the connector element. The connector element also includes a plurality of leads, wherein each lead connects a corresponding wire connector terminal with a corresponding contact terminal. The plurality of leads include a plurality of layers of leads.

Abstract: In the termination of signal cables with two or more wire pairs, it is customary to effect a clamping of the cable in order to relieve the strain on the wires themselves and the terminal connections. This, however, results in an uncontrollable re-arrangement of the wire pairs with associated interference between them. With the invention, this is avoided in that the termination or the strain-relieving element is configured with mutually separated lead-in passages for the individual wire pairs, and with associated clamping means for each of the wire pairs led through the passage. There is hereby achieved a well-controlled electrical separation between the wire pairs, and also an improved mechanical strain relief, i.e. by a primary clamping of the wire pairs themselves. By using a wedge part for insertion into the end of the cable, it can be ensured that the wire pairs extend from the end of the cable in an evenly inclining manner, whereby signal reflections from the area will be minimised.

Abstract: A connector element for making a connection between electrical conductors in a network. The connector element has a front, a rear and a length between the front and the rear. The connector element includes a plurality of contact terminals arranged in at least one plane at the front of the connector element. The plurality of contact terminals are configured for connection with corresponding contact terminals of a mating connector element. The connector element includes a plurality of wire connector terminals arranged in first and second rows at substantially the rear of the connector element. The connector element also includes a plurality of leads, wherein each lead connects a corresponding wire connector terminal with a corresponding contact terminal. The plurality of leads include a plurality of layers of leads.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.