Patents by Inventor Upvan Narang
Upvan Narang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7255874Abstract: Biocompatible polymers and adhesives have a cyanoacrylic core and other substituents such as therapeutic agents, targeting moieties, imaging agents, amino acid residues or other organic moieties. Exemplary uses of inventive compositions include use as sealants and adhesives for medical uses, and as polymeric formulations for biocompatible implants and matrices and drug delivery.Type: GrantFiled: December 21, 2001Date of Patent: August 14, 2007Assignee: Closure Medical CorporationInventors: John S. Bobo, Julian A. Quintero, Jerry Y. Jonn, Joe B. Barefoot, Jeffrey G. Clark, Upvan Narang, Scott Marc Cannizaro, J. Christopher Marmo
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Publication number: 20050196431Abstract: An applicator tip for an applicator for applying a polymerizable monomeric adhesive composition can include a bioactive material, a flavorant, a polymerization initiator, and/or a polymerization rate modifier.Type: ApplicationFiled: May 2, 2005Publication date: September 8, 2005Inventors: Upvan Narang, William Nicholson, Daniel Hedgpeth, Gabriel Szabo, Ibraheem Badejo, Joe Barefoot, William Cotter, Keith D'Alessio, Anthony Sherbondy
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Publication number: 20050047846Abstract: A single use applicator for applying an adhesive material, particularly for medical use, includes a semi-rigid base strip having a longitudinal direction, and a reservoir containing an adhesive material, the reservoir being secured to one side of the base strip. The base strip is arranged to be folded about an axis substantially perpendicular to the longitudinal direction such that a portion of the reservoir is ruptured and pressure is applied on the reservoir to expel the adhesive material from the ruptured reservoir. In embodiments, the base strip has a hole formed therethrough and a projection corresponding to the hole formed on one side thereof. The reservoir is disposed over the hole on a side of the base strip opposite the one side on which the projection is formed. When the base strip is folded, the projection extends into the hole to apply pressure on the reservoir.Type: ApplicationFiled: August 28, 2003Publication date: March 3, 2005Applicant: CLOSURE MEDICAL CORPORATIONInventors: Upvan Narang, Gabriel Szabo, Jack Goodman
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Publication number: 20050042266Abstract: A monomeric adhesive composition includes a polymerizable monomer, such as a 1,1-disubstituted monomer such as a cyanoacrylate, and an antimicrobial agent, wherein the antimicrobial agent is a phenolic active compound. Examples of suitable phenolic active compounds include halogenated phenol compounds such as chlorinated phenol compounds (such as triclosan) and brominated phenol compounds.Type: ApplicationFiled: August 21, 2003Publication date: February 24, 2005Applicant: CLOSURE MEDICAL CORPORATIONInventor: Upvan Narang
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Publication number: 20040223946Abstract: A method of treating insect bites includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with an insect bite, optionally with at least one of an additional active agent, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: ApplicationFiled: May 5, 2003Publication date: November 11, 2004Applicant: Closure Medical CorporationInventors: Clark J. Kidd, Daniel L. Hedgpeth, Upvan Narang, Gabriel N. Szabo
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Publication number: 20040223932Abstract: A method of treating acne includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with acne, optionally with at least one of an additional anti-acne agent or other active agent, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: ApplicationFiled: May 5, 2003Publication date: November 11, 2004Applicant: Closure Medical CorporationInventors: Daniel L. Hedgpeth, Upvan Narang
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Patent number: 6802416Abstract: A package assembly or kit can be used in conjunction with storing and dispensing adhesive materials. The package assembly can include an enclosure in which an applicator and a container may be positioned. The container contains adhesive material. The enclosure may include a base and a cover. The base preferably includes one or more cavities, with at least one applicator disposed in one of the cavities. Further, the container may be disposed in another of the cavities. The cover may be provided with a plurality of wells. The container may include a restrictor positioned within a neck of the container. The restrictor is provided to limit the volume of adhesive material retained in an absorbent end of an applicator such as a swab. The package assembly can be provided in a sterilized condition.Type: GrantFiled: August 30, 1999Date of Patent: October 12, 2004Assignee: Closure Medical CorporationInventors: Keith R. D'Alessio, Gary F. Prokop, Leonard F. Czuba, Carl F. Behrend, Peter J. Kopec, Upvan Narang, Gabriel N. Szabo, Anthony S. Voiers, Cheryl A. Kennedy
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Patent number: 6779657Abstract: A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material includes: a base portion having at least one sealed compartment; a polymerizable monomeric adhesive material contained in the compartment; an applicator at least partially disposed in the compartment such that a tip of the applicator is proximate the adhesive material. The at least one sealed compartment may comprise first and second sealed compartments that are separated with the polymerizable monomeric adhesive material contained in the first compartment and the applicator at least partially disposed in the second compartment. Alternatively, the first and second compartments may be open to each other. In such case, the applicator assembly may further comprise a plunger that defines the second compartment and that is movable into the first compartment to displace the adhesive material into the second compartment. A kit can include multiple applicator assemblies that are separate or frangibly connected.Type: GrantFiled: June 6, 2001Date of Patent: August 24, 2004Assignee: Closure Medical CorporationInventors: Lawrence H. Mainwaring, Upvan Narang
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Patent number: 6767552Abstract: A method of treating or preventing oral fungal infection includes applying a polymerizable monomer adhesive composition to an area afflicted with or susceptible to oral fungal infection, optionally with at least one of an additional anti-fungal agent, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area.Type: GrantFiled: July 5, 2001Date of Patent: July 27, 2004Assignee: Closure Medical CorporationInventor: Upvan Narang
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Publication number: 20040137067Abstract: An applicator tip for an applicator for applying a polymerizable monomeric adhesive composition can include a bioactive material, a flavorant, a polymerization initiator, and/or a polymerization rate modifier.Type: ApplicationFiled: November 13, 2003Publication date: July 15, 2004Applicant: Closure Medical CorporationInventors: Upvan Narang, William M. Cotter, Keith R. D'Alessio, Anthony Sherbondy, Gabriel N. Szabo
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Patent number: 6746667Abstract: A method of treating or preventing tinea pedis, commonly known as Athlete's Foot, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea pedis, optionally with at least one of an additional anti-fungal agent or a foot care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: GrantFiled: July 5, 2001Date of Patent: June 8, 2004Assignee: Closure Medical CorporationInventors: Ibraheem Badejo, Daniel L. Hedgpeth, Upvan Narang, William S. C. Nicholson, Andres Rivera, Mary Jo S. Rivera, Anthony Sherbondy, Gabriel N. Szabo
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Patent number: 6607631Abstract: A polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an absence of the slip additive. The slip additive can be selected from, inter alia, fluorinated monomers or polymers, fluorinated additives, siloxane-containing monomers or polymers, siloxane-containing additives, fluorinated siloxanes, and long chain fatty acid esters. The slip additive can also form a second phase in a resultant polymer film, where the second phase is soluble in the monomer but is insoluble or substantially insoluble in the polymer.Type: GrantFiled: September 8, 2000Date of Patent: August 19, 2003Assignee: Closure Medical CorporationInventors: Ibraheem T. Badejo, Wendy Y. Su, Keith R. D'Alessio, Jerry Jonn, Julian A. Quintero, Michelle Knotts, Timothy P. Hickey, Lawrence H. Mainwaring, Upvan Narang
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Patent number: 6602496Abstract: A method of treating or preventing tinea corporis, commonly known as ringworm of the skin, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea corporis, optionally with at least one of an additional anti-fungal agent or a skin care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: GrantFiled: July 5, 2001Date of Patent: August 5, 2003Assignee: Closure Medical CorporationInventors: Daniel L. Hedgpeth, William S. C. Nicholson, Upvan Narang, Anthony Sherbondy, Gabriel N. Szabo
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Patent number: 6595940Abstract: A disposable applicator includes a generally tubular applicator body having a closed proximal end and an open distal end and a frangible vial inside. The proximal end is covered by a drying swab while the distal end is covered by an applicator swab that is in open communication with the interior of the applicator body. Within the applicator body is a frangible vial containing a biomedically useful liquid composition, such as an &agr;-cyanoacrylate adhesive, a medicament, or both. The applicator is useful for applying liquid compositions to target sites such as tissue, particularly sites of topical pathology, such as stomatitis lesions.Type: GrantFiled: October 29, 1999Date of Patent: July 22, 2003Assignee: Closure Medical CorporationInventors: Keith R. D'Alessio, William M. Cotter, Upvan Narang, Lawrence H. Mainwaring, Ibraheem T. Badejo, Daniel L. Hedgpeth, Gabriel N. Szabo, Anthony Sherbondy, Joe B. Barefoot
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Patent number: 6585967Abstract: A method of treating or preventing tinea cruris, commonly known as Jock Itch, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea cruris, optionally with at least one of an additional anti-fungal agent or a skin care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: GrantFiled: July 5, 2001Date of Patent: July 1, 2003Assignee: Closure Medical CorporationInventors: Upvan Narang, William S. C. Nicholson, Anthony Sherbondy, Gabriel N. Szabo
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Patent number: 6579469Abstract: An adhesive composition that contains a preservative is particularly useful as a medical adhesive and can include alkyl cyanoacrylate monomers. The preservative is preferably soluble in the monomer. The composition may optionally be sterilized by placing a mixture of a polymerizable adhesive monomer and a preservative in a container, sealing the container, and sterilizing the mixture and the container.Type: GrantFiled: October 29, 1999Date of Patent: June 17, 2003Assignee: Closure Medical CorporationInventors: William S. C. Nicholson, Upvan Narang, Ubonwan A. Stewart, Daniel L. Hedgpeth, Ibraheem T. Badejo, Lawrence H. Mainwaring
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Publication number: 20030060380Abstract: An adhesive remover composition and methods for removing medical grade and other adhesive compositions including, but not limited to, cyanoacrylate adhesive compositions from surfaces including, but not limited to, areas of tissue, including areas of compromised skin. The composition, which is preferably bio-compatible, includes a suitable remover compound such as an alkylester plasticizer combined with an antimicrobial preservative to protect the composition from microorganisms. A method of removing adhesive compositions includes applying the remover composition to the adhesive composition using an applicator, such as a spray applicator or a towelette, allowing the remover to interact with the adhesive composition and then removing the remover and the adhesive composition.Type: ApplicationFiled: September 26, 2001Publication date: March 27, 2003Applicant: Closure Medical CorporationInventors: Jaime Ayarza, Ibraheem T. Badejo, Joe B. Barefoot, Daniel L. Hedgpeth, Michelle M. Knotts, Bernard Malofsky, Upvan Narang, Gina L. Spath, Wendy Y. Su
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Publication number: 20030007946Abstract: A method of treating or preventing tinea cruris, commonly known as Jock Itch, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea cruris, optionally with at least one of an additional anti-fungal agent or a skin care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: ApplicationFiled: July 5, 2001Publication date: January 9, 2003Applicant: CLOSURE MEDICAL CORPORATIONInventors: Upvan Narang, William S. C. Nicholson, Anthony Sherbondy, Gabriel N. Szabo
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Publication number: 20030007947Abstract: A method of treating or preventing oral fungal infection includes applying a polymerizable monomer adhesive composition to an area afflicted with or susceptible to oral fungal infection, optionally with at least one of an additional anti-fungal agent, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area.Type: ApplicationFiled: July 5, 2001Publication date: January 9, 2003Applicant: CLOSURE MEDICAL CORPORATIONInventor: Upvan Narang
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Publication number: 20030007949Abstract: A method of treating or preventing tinea corporis, commonly known as ringworm of the skin, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea corporis, optionally with at least one of an additional anti-fungal agent or a skin care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.Type: ApplicationFiled: July 5, 2001Publication date: January 9, 2003Applicant: CLOSURE MEDICAL CORPORATIONInventors: Daniel L. Hedgpeth, William S. C. Nicholson, Upvan Narang, Anthony Sherbondy, Gabriel N. Szabo