Patents by Inventor Uwe Peters

Uwe Peters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
    Patent number: 6972299
    Abstract: This invention relates to a compound and the use of the compound of the formula wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH?CH— or —C?C—; and B signifies wherein R6 to R26, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: December 6, 2005
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
    Patent number: 6927232
    Abstract: This invention relates to the treatment of mGluR5 receptor mediated disorders, which comprises administering to a person in need of treatment a compound having the formula wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH?CH— or —C?C—; and B signifies wherein R6 to R26, X and Y are as defined herein.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: August 9, 2005
    Assignee: Hoffman-La Roche Inc.
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Substituted imidazo[1,2-a]pyridine derivatives
    Patent number: 6916826
    Abstract: The present invention is a series of novel compounds of formula I and a method of treatment or prevention of a mGluR5 receptor mediated disease by administering an therapeutically effective amount of a compound formula wherein R1 and R2 are selected from hydrogen, (C1-6)-alkyl, halogen, hydroxy, (C1-6)-alkoxy and A is defined the description, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: July 12, 2005
    Assignee: Hoffman-La Roche Inc.
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Pyridine and pyrimidine derivatives
    Publication number: 20050143405
    Abstract: The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
    Type: Application
    Filed: January 18, 2005
    Publication date: June 30, 2005
    Inventors: Markus Boehringer, Bernd Loeffler, Jens-Uwe Peters, Matthias Steger, Peter Weiss
  • Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
    Publication number: 20050131043
    Abstract: This invention relates to a compound and the use of the compound of the formula wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH?CH— or —C?C—; and B signifies wherein R6 to R26, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.
    Type: Application
    Filed: January 18, 2005
    Publication date: June 16, 2005
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Dual NK1/NK3 receptor antagonists
    Publication number: 20050090533
    Abstract: The present invention provides a method for the treatment of schizophrenia which comprises administering a compound of formula wherein the substituents are as described herein or a pharmaceutically active acid-addition salt thereof. In particular, the invention provides methods for treating both positive and negative symptoms of schizophrenia through dual inhibition of NK1 and NK3 receptors. The invention also provides novel compounds with formula I and methods for preparing compounds of the invention.
    Type: Application
    Filed: July 2, 2004
    Publication date: April 28, 2005
    Inventors: Torsten Hoffmann, Andreas Koblet, Jens-Uwe Peters, Patrick Schnider, Andrew Sleight, Heinz Stadler
  • Carbamic acid alkyl ester derivatives
    Publication number: 20050075327
    Abstract: The present invention provides compounds of the general formula wherein R4 is one of the following groups and R1, R2, R3, R7, R8, and R9 are as defined in the specification and pharmaceutically acceptable salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. The compounds are useful for the treatment of Alzheimer's disease.
    Type: Application
    Filed: September 27, 2004
    Publication date: April 7, 2005
    Inventors: Alexander Flohr, Guido Galley, Roland Jakob-Roetne, Eric Kitas, Jens-Uwe Peters, Wolfgang Wostl
  • Pyridine and pyrimidine derivatives
    Patent number: 6867205
    Abstract: The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: March 15, 2005
    Assignee: Hoffman-La Roche Inc.
    Inventors: Markus Boehringer, Bernd Michael Loeffler, Jens-Uwe Peters, Matthias Steger, Peter Weiss
  • Malonamide derivatives
    Publication number: 20050054633
    Abstract: The invention relates to malonamide derivatives of formula wherein each of the variables are as defined herein and to pharmaceutically acceptable acid addition salts, optically pure enantiomers, racemates and diastereomeric mixtures thereof. These compounds are ?-secretase inhibitors and may be used for the treatment of Alzheimer's disease.
    Type: Application
    Filed: September 2, 2004
    Publication date: March 10, 2005
    Inventors: Alexander Flohr, Guido Galley, Roland Jakob-Roetne, Eric Kitas, Jens-Uwe Peters, Wolfgang Wostl
  • Substituted imidazo [1,2-a] pyridine derivatives
    Patent number: 6861437
    Abstract: The present invention is a series of novel compounds of formula I and a method of treatment or prevention of a mGluR5 receptor mediated disease by administering an therapeutically effective amount of a compound formula wherein R1 and R2 are selected from hydrogen, (C1-6)-alkyl, halogen, hydroxy, (C1-6)-alkoxy and A is defined the description, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: March 1, 2005
    Assignee: Hoffman-La Roche Inc.
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Benzoxazepinone derivatives
    Publication number: 20040235819
    Abstract: The invention relates to benzoxazepinone derivatives of formula 1
    Type: Application
    Filed: May 3, 2004
    Publication date: November 25, 2004
    Inventors: Guido Galley, Robert Alan Goodnow, Jens-Uwe Peters
  • Malonamide derivatives
    Publication number: 20040220222
    Abstract: The invention relates to malonamide derivatives of formula 1
    Type: Application
    Filed: January 29, 2004
    Publication date: November 4, 2004
    Inventors: Guido Galley, Annick Goergler, Helmut Jacobsen, Eric Argirios Kitas, Jens-Uwe Peters
  • Pyridine and quinoline derivatives
    Patent number: 6800650
    Abstract: The present invention provides compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: October 5, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Markus Boehringer, Bernd Michael Loeffler, Jens-Uwe Peters, Claus Riemer, Peter Weiss
  • Honing method
    Patent number: 6793560
    Abstract: A honing method proposes that using an arbor honing tool a remachining be carried out using the same tool either simultaneously or following onto arbor honing, in which the ratio of the stroke speed to the rotational speed of the tool is significantly increased. This leads to a cross-structure of the honing tracks allowing a better oil holding capacity.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: September 21, 2004
    Assignee: Nagel Maschinen-und Werkzeugfabrik GmbH
    Inventors: Uwe-Peter Weigmann, Peter Schuele
  • Substituted imidazo[1,2-a]pyridine derivatives
    Publication number: 20040180921
    Abstract: The present invention is a series of novel compounds of formula I and a method of treatment or prevention of a mGluR5 receptor mediated disease by administering an therapeutically effective amount of a compound formula 1
    Type: Application
    Filed: March 25, 2004
    Publication date: September 16, 2004
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
    Patent number: 6706707
    Abstract: This invention relates to a compound and the use of the compound of the formula wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifies wherein R6 to R26, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: March 16, 2004
    Assignee: Hoffman-La Roche Inc.
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
    Publication number: 20030225070
    Abstract: This invention relates to the treatment of mGluR5 receptor mediated disorders, which comprises administering to a person in need of treatment a compound having the formula 1
    Type: Application
    Filed: April 4, 2003
    Publication date: December 4, 2003
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Pyridine and pyrimidine derivatives
    Publication number: 20030216382
    Abstract: The present invention provides compounds of formula (I) 1
    Type: Application
    Filed: February 10, 2003
    Publication date: November 20, 2003
    Inventors: Markus Boehringer, Bernd Michael Loeffler, Jens-Uwe Peters, Matthias Steger, Peter Weiss
  • Substituted imidazo [1,2-a] pyridine derivatives
    Publication number: 20030212096
    Abstract: The present invention is a series of novel compounds of formula I and a method of treatment or prevention of a mGluR5 receptor mediated disease by administering an therapeutically effective amount of a compound formula 1
    Type: Application
    Filed: April 4, 2003
    Publication date: November 13, 2003
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
    Publication number: 20030208082
    Abstract: This invention relates to a compound and the use of the compound of the formula 1
    Type: Application
    Filed: March 25, 2003
    Publication date: November 6, 2003
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann