Abstract: Compositions comprising a therapeutically effective amount of a multikinase inhibitor, such as nintedanib or axitinib or pazopanib, are provided, wherein the composition is an emulsion, such as a nanoemulsion, with lipophilic carrier (e.g., castor oil), a polyoxyl oil (e.g., polyolyl-35 castor oil), optionally with a surfactant (e.g., polysorbate 80), optionally with a cyclic oligosaccharide, such as a cyclodextrin (e.g., 2-hydroxypropyl-beta-cyclodextrin), as a solubilizer. Methods for treating ocular conditions with the compositions are also provided.

Abstract: The composition is an herbal supplement comprised of hydrolyzed whole soybean, Bacillus amyloliquefaciens, lactic acid bacteria, the mushroom, Auricularia polytricha, and turmeric. The soybean feeds the bacterial components of the composition to increase their biomass. The Bacillus amyloliquefaciens produces protease and amylase enzymes which hydrolyze the proteins and carbohydrates in the soybean into smaller peptides and oligosaccharides. These smaller nutrients are more easily absorbed by the gastrointestinal tract. The lactic acid bacteria are probiotics which limit the growth of Bacillus amyloliquefaciens in the composition thus balancing the gastrointestinal microbiome. The mushroom, Auricularia polytricha enhances blood flow, removes toxins from the bowel, stabilizes the digestive system and enhances digestion. Turmeric is an antioxidant, anti-ulcer, anti-bacteria (including the suppression of Helicobacter pylori bacteria), anti-inflammatory.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: The method includes treating bone and joint diseases with a composition which includes collagen, essential minerals, and mineral lactate which were derived from the bones of crocodilos reptilia (crocodile). Crocodile collagen is made of a different ratio of amino acids than mammalian collagen which may be at least partly responsible for its therapeutic properties. The composition further includes a mixture of herbs. The mixture of herbs may include Clinacanthus nutans, Eclipta prostrata, Drynaria rhizome, and Auricularia polytricha. The herbs in the mixture of herbs each has one or more of the following properties: anti-inflammatory, analgesic, bone formation enhancement, and increases the number of osteoblast proliferation without impacting the number or activity of osteoclasts. The composition may also include essential minerals which are important for bone formation.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.

Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.

Abstract: The method includes treating bone and joint diseases with a composition which includes collagen, essential minerals, and mineral lactate which were derived from the bones of crocodilos reptilia (crocodile). Crocodile collagen is made of a different ratio of amino acids than mammalian collagen which may be at least partly responsible for its therapeutic properties. The composition further includes a mixture of herbs. The mixture of herbs may include Clinacanthus nutans, Eclipta prostrata, Drynaria rhizome, and Auricularia polytricha. The herbs in the mixture of herbs each has one or more of the following properties: anti-inflammatory, analgesic, bone formation enhancement, and increases the number of osteoblast proliferation without impacting the number or activity of osteoclasts. The composition may also include essential minerals which are important for bone formation.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: A memory circuit is configured for storage of completion queues. Each completion queue can store completion descriptors associated with transfers of data from interrupt source circuits to the memory circuit. A direct memory access circuit provides access to the memory circuit for the interrupt source circuits. An interrupt engine issues interrupt messages for processing the completion descriptors in the completion queues in response to satisfaction of a set of trigger conditions specified in an active interrupt moderation mode. The active interrupt moderation mode is one of multiple available interrupt moderation modes. The interrupt engine bypasses issuing interrupt messages in response to the set of trigger conditions of the active interrupt moderation mode not being satisfied.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.