Abstract: An adaptive audio rendering system is disclosed for conditioning an individual to real-world environments through variable audio output in computer simulations. The subject is fully or partially immersed in a computer-simulated environment for a time-limited session. Real-time monitoring of the human subject is performed for a change in a sensor-derived, quantified sensory load level. Responsive to an increase in sensory load level, the computer-simulated environment modulates the quantity of audio information such as background noise, background dialog, foreground dialog and foreground noise. The human subject adapts to increasingly complex environments by this modulation of audible information.

Abstract: An adaptive computer simulation rendering system is disclosed for conditioning an individual having Autism Spectrum Disorder (ASD) to real-world environments through variable sensory output in computer simulations. The subject is fully or partially immersed in a computer-simulated environment for a time-limited session. Real-time monitoring of the human subject is performed for a change in a sensor-derived, quantified sensory load level. Responsive to an increase in sensory load level, the computer-simulated environment modulates the sensor load on the individual. The human subject adapts to increasingly complex environments by this modulation of simulation thereby providing therapeutic benefit to the individual with ASD.

Abstract: An adaptive computer simulation rendering system is disclosed for conditioning an individual suffering from a stress disorder, such as post-traumatic stress disorder (PTSD), to real-world environments through variable sensory output in computer simulations. The subject is fully or partially immersed in a computer-simulated environment for a time-limited session. Real-time monitoring of the human subject is performed for a change in a sensor-derived, quantified sensory load level. Responsive to an increase in sensory load level, the computer-simulated environment modulates the sensor load on the individual. The human subject adapts to increasingly complex environments by this modulation of simulation.

Abstract: Introduced here are technologies for examining an image of an airline passenger, while the passenger is onboard. The image may be examined for abnormalities, the passenger's mood, and/or the passenger's expression. The image analysis may be supplemented by data from a suite of sensors such as heart rate monitors, accelerometers, gyroscopes, and the like. The image and the sensor data are then analyzed to detect abnormalities, identify related recommendations, and suggest products and services offered onboard or at the destination that are related to the abnormalities and recommendations. The general purpose is to improve an airline passenger's travel experience while on board the flight.

Abstract: The present disclosure relates generally to therapeutic agents that may be useful as inhibitors of Integrated Stress Response (ISR) pathway.

Abstract: Ultrasonic surgical instruments including a handle housing, a switch frame, and a switch assembly are disclosed. The switch assembly may include a first switch arrangement movably supported on a distal portion of the handle housing and selectively movable relative to a first switch contact supported by the switch frame. The switch assembly may further include a second switch arrangement including a right switch button movably supported on a right side of the handle housing and selectively movable relative to a right switch contact supported by the switch frame, and a left switch button movably supported on a left side of the handle housing and selectively movable relative to a left switch contact supported by the switch frame. The first and second switch arrangements may be configured to be selectively actuatable by a single hand supporting the handle housing.

Abstract: A system can include one or more sensors at a wellsite. The system can detect first emission data about emissions with respect to a wellbore over a first period of time. The system can detect second emission data about emissions with respect to the wellbore over a second period of time. The system can determine an adjustment to a plug and abandonment operation with respect to the wellbore based on the first emission data. The system can determine an amount of reduction in emissions from the wellbore using the first emission data and the second emission data. The system can output the amount of reduction in the emissions.

Abstract: A device for hydrating particulate bone material is provided. The device comprises a tubular member having an interior surface and an exterior surface. The interior surface is configured to receive the particulate bone material and a hydration fluid. The exterior surface has a plurality of pores configured to allow the hydration fluid to flow into the interior surface of the tubular member and hydrate the particulate bone material. The plurality of pores are smaller in size than the particulate bone material. Methods of dispensing particulate the bone material are also provided.

Abstract: A biostimulant composition produced from hydrolysis of various feedstock are provided.

Abstract: Compounds that regulate quorum sensing in Staphylococcal bacteria and in particular in Staphylococcus aureus are provided. Compounds provided are racemic, non-racemic or substantially enantiomerically pure cyclic peptides of formula I: or salts or solvates thereof, where variables R, W, X1, X2, and Z and are as described in the specification and L1 is a divalent linker which contains 1-12 carbon atoms, optionally 1-4 oxygen atoms, optionally one or two carbon-carbon double bonds, and hydrogen atoms to satisfy valency. Certain dimers of the cyclic peptides are also provided. One or more cylic peptides or dimers thereof herein can be employed to inhibit QS and to thus inhibit virulence in Staphylococcus bacteria. Compounds herein and pharmaceutical compositions containing one or more of these compounds are useful in treating infections of Staphylococcus bacteria. Methods for treating such bacterial infections are also provided.

Abstract: A method of treating a spine includes implanting a spinal implant within a patient. The spinal implant includes a first member having a first wall defining an axial passageway and a first opening, the first opening being in communication with the axial passageway. A second member includes a second wall defining an axial channel having the first member disposed therein, the second wall defining a second opening in communication with the axial channel. Bone graft is injected through the first opening and into the axial passageway and through the second opening and into the axial channel after the spinal implant is implanted within the patient.

Abstract: Systems, devices, and methods for digitally altering redeemed wagering tickets include a processor circuit for performing operations. A memory coupled to the processor circuit includes machine-readable instructions that, when executed by the processor circuit, cause the processor circuit to receive an indication that a player has inserted a wagering ticket into an acceptor of a gaming device and cause an image capture device to generate a digital image of the wagering ticket. The processor digitally alters the digital image of the wagering ticket to form a digitally altered digital image. The digitally altered digital image includes a paid indication indicative that the wagering ticket has been redeemed, an amount indication indicative of an amount paid for the wagering ticket, and a time indication indicative of a time period associated with redemption of the wagering ticket.

Abstract: Anti-CD3 binding domains and antibodies comprising them, including multispecific antibodies, with, inter alia, desirable T-cell activation and (re)directed target cell killing potency and developability, profiles are provided, as well as methods for their identification, isolation, and generation, and methods for their preparation and use. Reagents for identifying, isolating, selecting, generating and characterizing CD3 binding domains and antibodies comprising them are also provided.

Abstract: The present disclosure relates to a device, comprising a first inverter, wherein the first inverter is configured to invert a DC input voltage into an AC output voltage, a first controller, wherein the first controller is configured to provide a reference voltage for the first inverter on the basis of an AC output current of the first inverter, a second inverter, wherein the second inverter is configured to invert a DC input voltage into an AC output voltage, a second controller, wherein the second controller is configured to provide a reference voltage for the second inverter on the basis of an AC output current of the second inverter, wherein the first inverter and the first controller form a first Hopf oscillator, wherein the second inverter and second controller form a second Hopf oscillator, and wherein the first Hopf oscillator is coupled to the second Hopf oscillator.

Abstract: A Magnetic Tunnel Junction (MTJ) device can include a second Precessional Spin Current (PSC) magnetic layer of Ruthenium (Ru) having a predetermined thickness and a predetermined smoothness. An etching process for smoothing the PSC magnetic layer can be performed in-situ with various deposition processes after a high temperature annealing of the MTJ formation.

Abstract: A protector assembly for handling, storing and transporting donor tissue in a transfer pipette includes a distal cap and a proximal plug that are respectively engageable with opposite ends of the pipette. Structurally, the pipette includes a distally tapered fluid chamber which is in fluid communication with an extension tube. The distal cap is dimensioned for friction engagement with the fluid chamber of the pipette and it is formed with a plurality of vents to establish fluid communication through the vents with the fluid chamber. On the other hand, the proximal plug is dimensioned for a friction engagement with the extension tube to prevent leakage of solution from the fluid chamber of the pipette when the proximal plug is engaged with the pipette. In combination, an engagement of the protector assembly with a pipette holding a donor tissue will protect and preserve the donor tissue during handling and transport.

Abstract: Caprolactam-derived solvents for use as processing solvents and/or coalescing agents for polyurethane dispersions (PUDs). The caprolactam-derived solvents are suitable for processing solvents and coalescing agents in PUDs created through traditional PUD manufacturing processes or as coalescing agents in PUDs created through solvent-free PUD manufacturing processes. Blends of more than one caprolactam-derived solvent may be used as the processing solvent and/or coalescing agent.

Abstract: An electronic gaming machine includes a cabinet, a display mounted to the cabinet, a wireless interface for communicating with a portable electronic device, a network interface for communicating with a validation server, a bill validator coupled to a game controller configured to accept bills and printed ticket vouchers, and a removable cash box. The game controller includes a processor and a memory configured to control a wager-based game played on the EGM, redeem virtual ticket vouchers and printed ticket vouchers, receive an indication to transfer value to the EGM via a virtual ticket voucher, receive the virtual ticket voucher including a virtual ticket voucher validation number from the portable electronic device via the wireless interface, validate the virtual ticket voucher with the validation server via the network interface, deposit a credit amount associated with the virtual ticket voucher, and notify the validation server that the virtual ticket voucher is redeemed.