Abstract: Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I? and I?? or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduces the excessive activation of complement.

Abstract: Systems and techniques are described herein for processing images. The systems and techniques can be implemented by various types of systems, such as by an extended reality (XR) system or device. In some cases, a first processor receives an image of an environment captured by an image sensor, identifies features depicted in the image, and generates descriptors for the features. The first processor sends the descriptors to a second processor, which may be more powerful than the first processor. The second processor receives the descriptors. The second processor associates the plurality of features with a map of the environment based on at least a subset of the plurality of descriptors. For example, the second processor can track at least a subset of the features based on at least a subset of the descriptors and based on feature information from one or more additional images of the environment.

Abstract: Methods and systems for providing software applications on a client device with dynamic control over low-latency mode (LLM) operations of the client device. The client device may monitor downlink data packets of a client software application operating on the client device to detect trigger events. The client device may determine operating parameters of the modem based on a detected trigger event and dynamically adjust the low-latency mode of the modem based on the detect trigger event or the determined operating parameters.

Abstract: A method may include generating, for a user of a computing device, an aggregator widget of the user. The computing device is connected to a monitor. The method may further include obtaining a list of windows currently being displayed on the monitor, determining that the list of windows being displayed on the monitor is empty, and in response to determining that the list of windows being displayed on the monitor is empty, displaying the aggregator widget on the monitor.

Abstract: A system and a method for determining one or more safe evacuation paths in an event of fire. A method includes receiving measurements of parameter/s from one or more detectors. The one or more detectors detect parameter/s in an event of fire in a premises and are positioned at each of a plurality of evacuation paths inside the premises. The method further includes determining one or more safe evacuation paths from the plurality of evacuation paths inside the premises based on the measurements of the parameter/s. The method also includes displaying an indication of each of the one or more safe evacuation paths on an interface of a user device based on the determination.

Abstract: A method and a system for warping a rendered frame is disclosed. On a host device of a split-rendering system, the method includes generating the rendered frame based on head tracking information of a user. The method also includes identifying a region of interest (ROI) of the rendered frame. The method also includes generating metadata for a warping operation from the ROI. The method further include transmitting the rendered frame and the metadata for a warping operation of the rendered frame. On a client device of the split-rendering system, the method includes transmitting head tracking information of a user by a client device. The method also includes receiving the rendered frame and metadata. The method further includes warping the rendered frame using the metadata and display pose information. The host device and the client device may be combined into an all-in-one head mounted display.

Abstract: The present disclosure relates to methods and apparatus for graphics processing. The apparatus can determine an eye-buffer including one or more bounding boxes associated with rendered content in a frame. The apparatus can also generate an atlas based on the eye-buffer, the atlas including one or more patches associated with the one or more bounding boxes. Additionally, the apparatus can communicate the atlas including the one or more patches. The apparatus can also calculate an amount of user motion associated with the rendered content in the frame. Further, the apparatus can determine a size of each of the one or more bounding boxes based on the calculated amount of user motion. The apparatus can also determine a size and location of each of the one or more patches in the atlas.

Abstract: The present disclosure relates to methods and apparatus for computer processing. Aspects of the present disclosure can determine at least one of a quality, latency, or capacity of a communication link for communication between a client device and a server. Aspects of the present disclosure can also determine a computational load for an application computation between the client device and the server. Moreover, aspects of the present disclosure can adjust a computational distribution for the application computation between the client device and the server based on at least one of the computational load for the application computation or the at least one of the quality, latency, or capacity of the communication link. Aspects of the present disclosure can also determine a computational capacity of at least one of the client device or the server.

Abstract: A method, a system, and a non-transitory computer readable medium are disclosed for a voice based application blocker. The method includes receiving, on a gateway, a text message from a mobile device; tokenizing, on a processor of the gateway, the text message into at least a user and a purpose, the purpose being denying or granting access of the user to one or more applications from the gateway; and creating, on a firewall of the gateway, blocking rules for the user to the one or more applications from the gateway.

Abstract: An improved wireless split rendering system for displaying Extended Reality (XR) content is discussed. A rendering server and client head-mounted device (HMD) may communicate over a wireless medium, where communication control is given to a server application layer logic. This allows the server to use request pose information from the HMD only when needed for rendering, while preserving bandwidth on the wireless medium for transmitting frames of the rendered content. This reduces contention and improves channel efficiency.

Abstract: The present disclosure relates to methods and apparatus for graphics processing. The apparatus can determine an eye-buffer including one or more bounding boxes associated with rendered content in a frame. The apparatus can also generate an atlas based on the eye-buffer, the atlas including one or more patches associated with the one or more bounding boxes. Additionally, the apparatus can communicate the atlas including the one or more patches. The apparatus can also calculate an amount of user motion associated with the rendered content in the frame. Further, the apparatus can determine a size of each of the one or more bounding boxes based on the calculated amount of user motion. The apparatus can also determine a size and location of each of the one or more patches in the atlas.

Abstract: Macrocyclic Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, Formula V, Formula VI, Formula VII, and Formula VIII or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.

Abstract: An improved wireless split rendering system for displaying Extended Reality (XR) content is discussed. A rendering server and client head-mounted device (HMD) may communicate over a wireless medium, where communication control is given to a server application layer logic. This allows the server to use request pose information from the HMD only when needed for rendering, while preserving bandwidth on the wireless medium for transmitting frames of the rendered content. This reduces contention and improves channel efficiency.

Abstract: The present disclosure relates to methods and apparatus for computer processing. Aspects of the present disclosure can determine at least one of a quality, latency, or capacity of a communication link for communication between a client device and a server. Aspects of the present disclosure can also determine a computational load for an application computation between the client device and the server. Moreover, aspects of the present disclosure can adjust a computational distribution for the application computation between the client device and the server based on at least one of the computational load for the application computation or the at least one of the quality, latency, or capacity of the communication link. Aspects of the present disclosure can also determine a computational capacity of at least one of the client device or the server.

Abstract: Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is an aryl, heteroaryl or heterocycle (R32) are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.

Abstract: Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.

Abstract: A server includes a processor configured to determine, based on reception of information from a client device, synchronization parameters between a server clock rate associated with the server and a client clock rate associated with the client device. The processor is also configured to determine a client-side generation timestamp for an audio frame based on the synchronization parameters and based on a server-side generation timestamp for the audio frame. The processor is further configured to generate the audio frame. The audio frame includes the client-side timestamp.

Abstract: An embodiment involves persistent storage and one or more processors. The persistent storage may contain a plurality of hardware models specifying types of computing devices, wherein the hardware models include attributes representing manufacturer names, product names, and model numbers of the computing devices. The processors may be configured to: obtain, from the persistent storage, a hardware model; calculate a hash value over attributes of the hardware model; compare the hash value to hash values in a curated list, the curated list including normalized hardware models that map the hash values to normalized manufacturer names, normalized product names, or normalized model numbers; determine that the hash value matches a particular hash value for a normalized hardware model; and update, in the persistent storage, the hardware model to include at least one of a normalized manufacturer name, a normalized product name, or a normalized model number associated with the normalized hardware model.

Abstract: Macrocyclic Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, Formula V, Formula VI, Formula VII, and Formula VIII or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.

Abstract: A system and a method for determining one or more safe evacuation paths in an event of fire. A method includes receiving measurements of parameter/s from one or more detectors. The one or more detectors detect parameter/s in an event of fire in a premises and are positioned at each of a plurality of evacuation paths inside the premises. The method further includes determining one or more safe evacuation paths from the plurality of evacuation paths inside the premises based on the measurements of the parameter/s. The method also includes displaying an indication of each of the one or more safe evacuation paths on an interface of a user device based on the determination.