Patents by Inventor Venkata R. Garigapati

Venkata R. Garigapati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyvalent polymers for the treatment of rotavirus infection
    Patent number: 6187762
    Abstract: The present invention includes polymerizable monomers comprising a fucoside moiety. In one embodiment, the monomer has a polymerizable functional group, such as an olefinic bond, to which the fucoside moiety is attached by a spacer group, for example, an alkylene group, or an alkylene group wherein one or more carbon atoms are substituted by heteroatoms, such as oxygen, nitrogen or sulfur atoms. The present invention also includes polymers comprising one or more fucoside moieties, such as pendant fucoside moieties, which can inhibit or prevent rotavirus infection in a mammal. Such a polymer can comprise, for example, a monomer of the present invention. The polymer can be a homopolymer or a copolymer, and can have, for example, a polyacrylamide, polyacrylate or polystyrene backbone.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: February 13, 2001
    Assignee: GelTex Pharmaceuticals, Inc.
    Inventors: W. Harry Mandeville, III, John S. Petersen, Venkata R. Garigapati, Thomas X. Neenan
  • Acid-functionalized saccharide monomers
    Patent number: 5939537
    Abstract: The present invention includes polymerizable monomers comprising an acid-functionalized glycoside moiety. The monomer can have a polymerizable functional group, such as an olefinic bond, to which the acid-functionalized glycoside moiety is attached by a spacer group, for example, an alkylene group, or an alkylene group wherein one or more carbon atoms are substituted by heteroatoms, such as oxygen, nitrogen or sulfur atoms. The present invention also includes polymers comprising pendant acid-functionalized glycoside moieties. The present invention also provides a method for treating a microbial infection in a mammal by administering to the mammal a therapeutically effective amount of a polymer comprising one or more acid-functionalized glycoside moieties.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: August 17, 1999
    Assignee: GelTex Pharmaceuticals Inc.
    Inventors: W. Harry Mandeville, III, Venkata R. Garigapati
  • Polyvalent polymers for the treatment of rotavirus infection
    Patent number: 5891862
    Abstract: The present invention includes polymerizable monomers comprising a fucoside moiety. In one embodiment, the monomer has a polymerizable functional group, such as an olefinic bond, to which the fucoside moiety is attached by a spacer group, for example, an alkylene group, or an alkylene group wherein one or more carbon atoms are substituted by heteroatoms, such as oxygen, nitrogen or sulfur atoms. The present invention also includes polymers comprising one or more fucoside moieties, such as pendant fucoside moieties, which can inhibit or prevent rotavirus infection in a mammal. Such a polymer can comprise, for example, a monomer of the present invention. The polymer can be a homopolymer or a copolymer, and can have, for example, a polyacrylamide, polyacrylate or polystyrene backbone.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: April 6, 1999
    Assignee: GelTex Pharmaceuticals, Inc.
    Inventors: W. Harry Mandeville, III, John S. Petersen, Venkata R. Garigapati, Thomas X. Neenan
  • Acid-functionalized saccharides as polyvalent anti-infectives
    Patent number: 5821312
    Abstract: The present invention includes polymerizable monomers comprising an acid-functionalized glycoside moiety. The monomer can have a polymerizable functional group, such as an olefinic bond, to which the acid-functionalized glycoside moiety is attached by a spacer group, for example, an alkylene group, or an alkylene group wherein one or more carbon atoms are substituted by heteroatoms, such as oxygen, nitrogen or sulfur atoms. The present invention also includes polymers comprising pendant acid-functionalized glycoside moieties. The present invention also provides a method for treating a microbial infection in a mammal by administering to the mammal a therapeutically effective amount of a polymer comprising one or more acid-functionalized glycoside moieties.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: October 13, 1998
    Assignee: GelTex Pharmaceuticals, Inc.
    Inventors: W. Harry Mandeville, III, Venkata R. Garigapati
  • Acid-functionalized saccharides as polyvalent anti-infectives
    Patent number: 5700458
    Abstract: The present invention includes polymerizable monomers comprising an acid-functionalized glycoside moiety. In one embodiment, the monomer has a polymerizable functional group, such as an olefinic bond, to which the acid-functionalized glycoside moiety is attached by a spacer group, for example, an alkylene group, or an alkylene group wherein one or more carbon atoms are substituted by heteroatoms, such as oxygen, nitrogen or sulfur atoms.The present invention also includes polymers comprising one or more acid-functionalized glycoside moieties, such as pendant acid-functionalized glycoside moieties, which can inhibit or prevent rotavirus infection in a mammal. Such a polymer can comprise, for example, a monomer of the present invention. The polymer can be a homopolymer or a copolymer, and can have, for example, a polyacrylamide, polyacrylate or polystyrene backbone.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: December 23, 1997
    Assignee: GelTex Pharmaceuticals Inc.
    Inventors: W. Harry Mandeville, III, Venkata R. Garigapati