Patents by Inventor Venkata Ramana Doppalapudi

Venkata Ramana Doppalapudi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 11311627
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: April 26, 2022
    Assignee: AVIDITY BIOSCIENCES LLC
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20220096647
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: October 12, 2021
    Publication date: March 31, 2022
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20220072145
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: August 31, 2021
    Publication date: March 10, 2022
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20220062434
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: November 17, 2021
    Publication date: March 3, 2022
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 11253607
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: February 22, 2022
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 11246941
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: February 15, 2022
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20220040323
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: October 12, 2021
    Publication date: February 10, 2022
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20220040322
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 10, 2022
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20220008550
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: September 1, 2021
    Publication date: January 13, 2022
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 11179472
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: November 23, 2021
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE DYSTROPHY
    Publication number: 20210299266
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
    Type: Application
    Filed: March 26, 2021
    Publication date: September 30, 2021
    Inventors: Venkata Ramana DOPPALAPUDI, Michael David HOOD, Rob BURKE, Michael Caramian COCHRAN, Beatrice Diana DARIMONT, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • Nucleic acid-polypeptide compositions and uses thereof
    Patent number: 11110180
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: September 7, 2021
    Assignee: AVIDITY BIOSCIENCES INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, Joel Daniel Arias, David Sai-Ho Chu, Michael Caramian Cochran, Rob Burke, Philip Kovach, Barbora Malecova
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND USES THEREOF
    Publication number: 20210261679
    Abstract: Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-transferrin receptor antibody described herein, and methods of treatment with use of an anti-transferrin receptor antibody described herein.
    Type: Application
    Filed: April 28, 2021
    Publication date: August 26, 2021
    Inventors: Beatrice Diana DARIMONT, Venkata Ramana DOPPALAPUDI, Rachel JOHNS
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20210187116
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: February 26, 2021
    Publication date: June 24, 2021
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
    Publication number: 20210179720
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Application
    Filed: February 26, 2021
    Publication date: June 17, 2021
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Rachel Elizabeth JOHNS, Palani BALU, Rob BURKE, Beatrice Diana DARIMONT
  • Anti-transferrin receptor antibodies and uses thereof
    Patent number: 11028179
    Abstract: Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-transferrin receptor antibody described herein, and methods of treatment with use of an anti-transferrin receptor antibody described herein.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: June 8, 2021
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Beatrice Diana Darimont, Venkata Ramana Doppalapudi, Rachel Johns
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND USES THEREOF
    Publication number: 20210130486
    Abstract: Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-transferrin receptor antibody described herein, and methods of treatment with use of an anti-transferrin receptor antibody described herein.
    Type: Application
    Filed: December 23, 2020
    Publication date: May 6, 2021
    Inventors: Beatrice Diana DARIMONT, Venkata Ramana DOPPALAPUDI, Rachel JOHNS
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 10994020
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: May 4, 2021
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • HETERODUPLEX NUCLEIC ACID MOLECULES AND USES THEREOF
    Publication number: 20210095283
    Abstract: Disclosed herein are heteroduplex nucleic acid molecules, heteroduplex nucleic acid conjugates, and pharmaceutical compositions for modulating a protein expression. Also described herein include methods of treating a disease or indication which utilize a heteroduplex nucleic acid molecule, a heteroduplex nucleic acid conjugate, or a pharmaceutical composition that comprises a heteroduplex nucleic acid molecule.
    Type: Application
    Filed: January 3, 2019
    Publication date: April 1, 2021
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Rachel Elizabeth JOHNS, Rob BURKE, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael David HOOD, Hanhua HUANG
  • Anti-transferrin receptor antibodies and uses thereof
    Patent number: 10913800
    Abstract: Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-transferrin receptor antibody described herein, and methods of treatment with use of an anti-transferrin receptor antibody described herein.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: February 9, 2021
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Beatrice Diana Darimont, Venkata Ramana Doppalapudi, Rachel Johns