Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).

Abstract: Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-transferrin receptor antibody described herein, and methods of treatment with use of an anti-transferrin receptor antibody described herein.

Abstract: Disclosed herein are antibody oligonucleotide conjugates and pharmaceutical compositions that induce an alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping. Also described herein include methods for treating muscle dystrophy including Duchenne muscular dystrophy that comprises administering antibody oligonucleotide conjugates or a pharmaceutical composition that induces alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping.

Abstract: An electronic device that selectively provides a trigger frame is described. During operation, the electronic device may receive a frame from a recipient electronic device, where the frame includes information that specifies a maximum uplink multi-user transmit duration of the recipient electronic device. Moreover, the electronic device may selectively provide the trigger frame to the recipient electronic device that specifies an uplink OFDMA frame or an uplink MIMO frame associated with the recipient electronic device. The trigger frame may be selectively provided when a transmit time corresponding to the uplink OFDMA frame or the uplink MIMO frame is less than or equal to the maximum uplink multi-user transmit duration.

Abstract: A database system includes a storage medium to store a semi-materialized view (MV) defined on an MV condition, the semi-MV including metadata containing references to objects containing data of one or more tables that satisfy the MV condition, the objects stored in a remote data store that is coupled to the database system over a network. The database system includes at least one processor to receive a query including a query condition, determine that the semi-MV can be used to satisfy the query based on the MV condition and the query condition, and use the metadata in the semi-MV to retrieve data of the objects in the remote data store for the query.

Abstract: Disclosed herein are system, method, and computer program product embodiments for utilizing non-RAM memory to implement a cloud storage system. An embodiment operates by receiving a request from an on-premises computer system to securely access a cloud drive by receiving an object specific template for an object. Based on the object specific template, an object specific plugin is selected, wherein the object specific plugin is configured to provide a connection to a cloud-based repository to obtain real time data for the object. An instance of the object is generated and communicated to a cloud plugin, wherein the cloud plugin is configured to communicate to a specific cloud drive through an HTTP client and further upload the instance of the object to the specific cloud drive.

Abstract: A memory subsystem and method for performing calibrations therein is disclosed. A memory subsystem includes a memory controller coupled to a memory by a plurality of signal paths. The memory controller is configured to perform an initial calibration to determine respective eye patterns corresponding to the ones of the plurality of signal paths. For a subsequent calibrations, updated eye patterns are determined for a subset of the plurality of signal paths. Remaining ones of the plurality of signal paths (not included in the subset), are not active during the subsequent calibrations. Updated eye patterns for the remaining ones of the plurality of signal paths are determined based on information obtained during the initial calibration and information from signal paths in the subset designated proxies for the remaining ones of the plurality of signal paths.

Abstract: Embodiments disclosed herein relate to enabling direct wireless device-to-device communication between sleepy end devices (SEDs) of a mesh (e.g., Thread®) network. A router may forward packets between end devices of the mesh network. However, if the router is not available, SEDs may not be able to communicate with each other using a mesh protocol. Embodiments presented herein enable end devices of the mesh network to communicate directly, without a router. Some embodiments are directed to changing a role of an end device to temporarily act as a router for a particular target end device. The role change may be based on a trigger event and may be temporary until a target action is performed by the target end device. In some embodiments, the end devices continue to operate as SEDs and use coordinated sampled listening techniques to communicate via the mesh protocol.

Abstract: Disclosed herein are system, method, and computer program product embodiments for utilizing non-RAM memory to implement a cloud storage system. An embodiment operates by receiving a request from an on-premises computer system to securely access a cloud drive by receiving an object specific template for an object. Based on the object specific template, an object specific plugin is selected, wherein the object specific plugin is configured to provide a connection to a cloud-based repository to obtain real time data for the object. An instance of the object is generated and communicated to a cloud plugin, wherein the cloud plugin is configured to communicate to a specific cloud drive through an HTTP client and further upload the instance of the object to the specific cloud drive.

Abstract: An electronic device that includes several antennas, at least one of which can receive signals communicated using a first type of wireless communication and at least another of which can transmit signals using a second type of wireless communication. The electronic device enables a signal to be transmitted in an unrestricted or restricted manner based on a criticality of data to be included in the signal.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).

Abstract: Methods and systems are presented for providing automated online chat assistance in an online chat session. One or more utterances transmitted from a user device of a user via the online chat session are obtained. The one or more utterances are provided to a first prediction model to predict an intent of a user. If it is determined that the first prediction model is unable to predict the intent of the user based on the one or more utterances, the one or more utterances are provided to a second prediction model. After predicting the intent of the user by the second prediction model, the intent is used by a chat robot to provide a dialogue with the user via the online chat session. The one or more utterances and the predicted intent are used to re-train the first prediction model.

Abstract: A synchronization system for synchronizing photons in a quantum teleportation network. The synchronization system includes a multiplexer combining a clock pulse with a signal photon (carrying a qubit) in an optical fiber, the optical fiber connecting a transmitter node (including the multiplexer) and a receiver node (comprising a demultiplexer). The signal photons have signal wavelengths red shifted as compared to clock wavelengths of the clock pulses. The clock pulses have an intensity below a threshold, such that Raman scattering of the clock pulses by the fiber (shifting the clock wavelengths into the signal wavelengths) is negligible. The receiver node comprises a demultiplexer demultiplexing the one of the signal photons and the one of the clock pulses; a first detector detecting the one of the signal photons; and a second detector detecting the one of the clock pulses.

Abstract: The present disclosure relates to several techniques for reducing the occurrence of data collisions, which can occur when multiple devices simultaneously transmit data in the same (frequency) channel. For example, a turnaround time in which a device switches from a receive mode of operation to a transmit mode of operation may be reduced based on the device and another device indicating that they are capable of operating with a reduced turnaround. As another example, devices may use learning-based turnaround estimation to determine a turnaround time supported by other devices and utilize the determined turnaround time, for instance, instead of a longer turnaround time. As yet another example, multiple clear channel assessments may be performed before transmitting data. For instance, a first clear channel assessment may be performed during a backoff period, and a second clear channel assessment may be performed afterwards before data is transmitted.

Abstract: Disclosed herein are system, method, and computer program product embodiments for utilizing non-RAM memory to implement a cloud storage system. An embodiment operates by receiving a request from an on-premises computer system to securely access a cloud drive by receiving an object specific template for an object. Based on the object specific template, an object specific plugin is selected, wherein the object specific plugin is configured to provide a connection to a cloud-based repository to obtain real time data for the object. An instance of the object is generated and communicated to a cloud plugin, wherein the cloud plugin is configured to communicate to a specific cloud drive through an HTTP client and further upload the instance of the object to the specific cloud drive.

Abstract: A method for preparing a graphene-nanosheets based concrete additive is disclosed. The method comprises mixing Polycarboxylate ether A (PCE-A) to a retarder - based salt solution to obtain a retarder-based Polycarboxylate ether A solution. In the next step, a retarder based PCE solution is obtained by adding Polycarboxylate ether B to the retarder based Polycarboxylate ether A solution to which graphene nanosheets are added. Further, an air entrainment agent is added to graphene nanosheets based PCE solution and further mixed to obtain the graphene nanosheets based concrete additive.

Abstract: Methods and devices are disclosed for supporting emergency service calls using dynamic service set identifier (SSID) deployment in a wireless communication network. An access point may receive an emergency service call request from a user device. The access point may also send a message with information about the received emergency service call request to a wireless network manager, and determine whether determining whether to serve the emergency service call request based on a response message received from the wireless network manager. In response to determining to serve the emergency service call request, the access point may create a new service set identifier (SSID) with emergency service call capability.

Abstract: An approach is described for a wireless device comprising a transceiver and a processor communicatively coupled to the transceiver. In a thread-based device, a thread radio coexists with a primary radio, such as a Bluetooth or WiFi radio. Because both radio share a common frequency band, the thread radio requests grants from the primary radio for transmission and reception. So as to avoid bogging down the primary radio, the thread radio throttles its requests. Specifically, the thread radio tracks certain variables indicative of the number of requests that have been made within a time window and the types of requests that have been made to the primary radio. By limiting the number of total requests and the number of requests of each type within the time window, the thread radio avoids overburdening the primary radio.