Patents by Inventor Vernon G. Wong

Vernon G. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190105330
    Abstract: The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a single administration of a minute dosage form into the anterior chamber of the eye provides for anti-inflammatory therapy following cataract surgery
    Type: Application
    Filed: December 10, 2018
    Publication date: April 11, 2019
    Inventors: Vernon G. WONG, William S. WHITE, Mae W. HU, Glenn T. HUANG, Faina KARASINA
  • Patent number: 10206934
    Abstract: Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 ?g/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 ?g/ml dexamethasone for at least about three weeks.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: February 19, 2019
    Assignee: Allergan, Inc.
    Inventors: Vernon G. Wong, Mae W. L. Hu
  • Patent number: 10159683
    Abstract: The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a single administration of a minute dosage form into the anterior chamber of the eye provides for anti-inflammatory therapy following cataract surgery.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: December 25, 2018
    Assignee: ICON BIOSCIENCE, INC.
    Inventors: Vernon G. Wong, William S. White, Mae W. Hu, Glenn T. Huang, Faina Karasina
  • Publication number: 20180303851
    Abstract: The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a single administration of a minute dosage form into the anterior chamber of the eye provides for anti-inflammatory therapy following cataract surgery
    Type: Application
    Filed: June 26, 2018
    Publication date: October 25, 2018
    Inventors: Vernon G. WONG, William S. WHITE, Mae W. HU, Glenn T. HUANG, Faina KARASINA
  • Publication number: 20180296765
    Abstract: The present embodiments provide for simple devices that guide the loading and dispensing of accurate small doses of fluid from standard injection syringes.
    Type: Application
    Filed: June 19, 2018
    Publication date: October 18, 2018
    Inventors: Vernon G. WONG, Tan PHAM, William S. WHITE, Glenn T. HUANG, Mae W. HU
  • Publication number: 20180289810
    Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.
    Type: Application
    Filed: June 11, 2018
    Publication date: October 11, 2018
    Applicant: Ramscor, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood
  • Publication number: 20180228898
    Abstract: This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.
    Type: Application
    Filed: March 28, 2018
    Publication date: August 16, 2018
    Applicant: Ramscor, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood
  • Patent number: 10028965
    Abstract: The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a single administration of a minute dosage form into the anterior chamber of the eye provides for anti-inflammatory therapy following cataract surgery.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: July 24, 2018
    Assignee: ICON BIOSCIENCE, INC.
    Inventors: Vernon G. Wong, William S. White, Mae W. Hu, Glenn T. Huang, Faina Karasina
  • Patent number: 10022502
    Abstract: Devices that guide the accurate loading and dispensing of predetermined doses of fluid from injection syringes are disclosed.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: July 17, 2018
    Assignee: ICON BIOSCIENCE, INC.
    Inventors: Vernon G. Wong, Tan Pham, William S. White, Glenn T. Huang, Mae W. Hu
  • Patent number: 9993558
    Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: June 12, 2018
    Assignee: Ramscor, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood
  • Publication number: 20180021352
    Abstract: Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodihle polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 ?g/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 ?g/ml dexamethasone for at least about three weeks.
    Type: Application
    Filed: October 2, 2017
    Publication date: January 25, 2018
    Inventors: Vernon G. Wong, Mae W.L. Hu
  • Patent number: 9814773
    Abstract: The present invention provides for injectable pharmaceutical sustained release formulations for delivery of active agents, particularly therapeutic proteins, to the eye. The formulations are biocompatible, biodegradable sustained release formulations comprising low-solubility liquid excipients and relatively small amounts (less than about 10%) of biocompatible, biodegradable polymer such as PLA or PLGA polymers. A unit dose of 5 ?L to 100 ?L of the formulation provides for sustained release of the agent for at least 14 days.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: November 14, 2017
    Assignees: Ramscor, Inc., Icon Bioscience, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood, Carol Wood, Glenn T. Huang
  • Patent number: 9775849
    Abstract: Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 ?g/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 ?g/ml dexamethasone for at least about three weeks.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: October 3, 2017
    Assignee: Allergan, Inc.
    Inventors: Vernon G. Wong, Mae W. L. Hu
  • Patent number: 9737606
    Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: August 22, 2017
    Assignee: Ramscor, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood
  • Publication number: 20170182064
    Abstract: Methods for reducing or preventing transplant rejection in the eye of an individual are described; comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
    Type: Application
    Filed: March 13, 2017
    Publication date: June 29, 2017
    Inventor: Vernon G. Wong
  • Patent number: 9636347
    Abstract: The present embodiments provide for methods of treating elevated intraocular pressure or glaucoma using a sustained release medicament consisting of prostaglandin in benzyl benzoate that is injected intraocularly no more frequently than once every two months.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: May 2, 2017
    Assignee: Icon Bioscience, Inc.
    Inventors: Vernon G. Wong, Mae W. Hu, Glenn T. Huang
  • Patent number: 9592242
    Abstract: Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: March 14, 2017
    Assignee: Allergan, Inc.
    Inventor: Vernon G. Wong
  • Patent number: 9474736
    Abstract: The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of ?-tocopheryl acetate; ?-tocopheryl acetate and about 0.5% aqueous component; or ?-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: October 25, 2016
    Assignee: Ramscor, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood
  • Publication number: 20160193230
    Abstract: Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
    Type: Application
    Filed: March 14, 2016
    Publication date: July 7, 2016
    Inventor: Vernon G. Wong
  • Publication number: 20160151386
    Abstract: The present embodiments provide for methods of treating elevated intraocular pressure or glaucoma using a sustained release medicament consisting of prostaglandin in benzyl benzoate that is injected intraocularly no more frequently than once every two months.
    Type: Application
    Filed: February 8, 2016
    Publication date: June 2, 2016
    Inventors: Vernon G. Wong, Mae W. Hu, Glenn T. Huang