Abstract: Implants comprising active agents are employed for introduction into a suprachoroidal space or an avascular region of an eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: Implants comprising active agents are employed for introduction into a suprachoroidal space or an avascular region of an eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: Intraocular administration of drugs such as .alpha.-2a interferon is employed in the treatment of age-related macular degeneration. Intraocular administration obviates the side effects associated with systemic administration, concentrates the drug at the site of the disease, and, where microcapsules are employed, provides continuous, long-lasting treatment.

Abstract: Implants comprising active agents are employed for introduction into a suprachoroidal space or an avascular region of an eye for therapeutic purposes. The administration of drags is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: Encapsulated agents are employed for introduction into the suprachoroid of an eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: An improved Schirmer I Tear Test is provided. The improvement comprises a strip having a graduated migration scale printed on the test strip and the presence of a water soluble marker dye that comigrates with the tear migration front. Both improvements serve to increase the reproducibility of the test and ease which with the results are read.

Abstract: Encapsulated drugs are employed for introduction into the chambers of the eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: A tonometer for measuring the intraocular pressure of an eye featuring an acoustic signaling system for determining the beginning of a pressure measurement. The acoustic system includes a consumable cap having a pair of annular raised surface portions spaced by a recessed area. The raised surface portions provide an eye-engaging surface at the face of the tonometer. A pressure transmitting plunger concentrically suspended between the raised surface portions by a plurality of spider arms combines with the eye-engaging surface to provide a contour which complements a shape of an eye. The recessed area is open along the eye-engaging surface, yet defines a generally enclosed volume when full tonometer-to-eye contact is made. Spaced apart inlet and outlet apertures within the recessed area permit channeling of an acoustic signal to and from the recessed area. Prior to proper coupling of the tonometer to an eye, a substantial amount of the energy of the acoustic signal is lost to free air.

Abstract: Microencapsulated drugs are employed for introduction into the chambers of the eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: An eye implant device for relieving excessive eye pressure due to glaucoma comprises a thin, elongated, resilient, semi-rigid body of biocompatible material such as polymethyl methacrylate, having surface channels extending along its length to provide drainage passages for eye fluids and transverse perforations through it spaced from each other along its length. Preferably the material of the body is wettable by the eye fluids, and the device curved along its length to match the curvature of the interior of the sclera of the eye in the limbal region. The longitudinal channels are preferably provided by corrugating the body of the device longitudinally, and the device is preferably cruciform in shape.