Patents by Inventor Victor C. Esch

Victor C. Esch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220244186
    Abstract: The invention generally relates to improved enhancement structures for use in surface-enhanced Raman scattering (SERS) and/or surface-enhanced fluorescence-based analysis.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 4, 2022
    Inventors: Steven Roy Julien Brueck, Xin Jin, Alexander Neumann, Victor C. Esch
  • Patent number: 11073513
    Abstract: The invention generally relates to using magnetic particles and alternating magnet fields to separate a target analyte from a sample. In certain embodiments, methods of the invention involve contacting a sample with magnetic particles including first moieties specific for a target analyte, thereby forming target/particle complexes in the sample, flowing the sample through a channel including second moieties attached to at least one surface of the channel, applying alternating magnetic fields to the flowing sample to result in target/particle complexes being brought into proximity of the surface to bind the second moieties and unbound particles remaining free in the sample, binding the target/particle complexes to the second moieties, and washing away unbound particles and unbound analytes of the sample.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: July 27, 2021
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Richard G. Saul, Andrew F. McDowell
  • Patent number: 10745763
    Abstract: The invention generally relates to a system for isolating or separating a target from a sample. In certain aspects, processes performed by the target capture system include introducing a plurality of magnetic particles, in which a plurality of the particles include at least one binding moiety specific to a target, into a sample to form at least one target/particle complex and applying a magnetic field to isolate the magnetic particle/target complexes from the sample. The process starts at inputting a sample into the system and ends at delivering a capture target or nucleic acids of the target into a container for further analysis.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: August 18, 2020
    Assignee: DNAE Group Holdings Limited
    Inventors: Ravil A. Sitdikov, Eddie W. Adams, Magdalena A. Torrance, David K. Aley, Erik J. Smith, Victor C. Esch
  • Patent number: 10677789
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: June 9, 2020
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Patent number: 10416155
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: September 17, 2019
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Publication number: 20180252709
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: May 2, 2018
    Publication date: September 6, 2018
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Patent number: 10045844
    Abstract: Methods of adjusting an intraocular lens after implantation. In some embodiments the methods include positioning an accommodating intraocular lens within an eye, the intraocular lens comprising an optic portion in fluid communication with a peripheral chamber, wherein movement of a fluid between the peripheral chamber and the optic portion in response to ciliary muscle movement changes the optical power of the lens, and reducing a power of the intraocular lens by causing the fluid to move between the optic portion and the peripheral chamber, wherein the reduction in power of the intraocular lens is not in response to ciliary muscle movement, and wherein the positioning step occurs prior to reducing the power.
    Type: Grant
    Filed: July 23, 2008
    Date of Patent: August 14, 2018
    Assignee: PowerVision, Inc.
    Inventors: Terah Whiting Smiley, John H. Shadduck, Victor C. Esch, John A. Scholl, Claudio Argento, Barry Cheskin, David John Smith, Denise H. Burns
  • Publication number: 20180143189
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: January 5, 2018
    Publication date: May 24, 2018
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Publication number: 20180136205
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 17, 2018
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Patent number: 9970931
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: May 15, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Patent number: 9869671
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: January 16, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Patent number: 9863940
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: January 9, 2018
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Publication number: 20170261501
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 14, 2017
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Publication number: 20170226564
    Abstract: The invention generally relates to a system for isolating or separating a target from a sample. In certain aspects, processes performed by the target capture system include introducing a plurality of magnetic particles, in which a plurality of the particles include at least one binding moiety specific to a target, into a sample to form at least one target/particle complex and applying a magnetic field to isolate the magnetic particle/target complexes from the sample. The process starts at inputting a sample into the system and ends at delivering a capture target or nucleic acids of the target into a container for further analysis.
    Type: Application
    Filed: March 20, 2017
    Publication date: August 10, 2017
    Inventors: Ravil A. Sitdikov, Eddie W. Adams, Magdalena A. Torrance, David K. Aley, Erik J. Smith, Victor C. Esch
  • Publication number: 20170227535
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Application
    Filed: April 25, 2017
    Publication date: August 10, 2017
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Patent number: 9696302
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: July 4, 2017
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
  • Patent number: 9671395
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: June 6, 2017
    Assignee: DNAE Group Holdings Limited
    Inventors: Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Victor C. Esch
  • Publication number: 20170145406
    Abstract: The invention generally relates to conducting an assay on a sample that isolates a bacterium from the sample, in which the assay isolates as low as about 1 CFU/ml of bacteria in the sample.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 25, 2017
    Inventors: Victor C. Esch, Sergey A. Dryga, Lisa-Jo Ann Clarizia
  • Patent number: 9599610
    Abstract: The invention generally relates to a system for isolating or separating a target from a sample. In certain aspects, processes performed by the target capture system include introducing a plurality of magnetic particles, in which a plurality of the particles include at least one binding moiety specific to a target, into a sample to form at least one target/particle complex and applying a magnetic field to isolate the magnetic particle/target complexes from the sample. The process starts at inputting a sample into the system and ends at delivering a capture target or nucleic acids of the target into a container for further analysis.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: March 21, 2017
    Assignee: DNAE Group Holdings Limited
    Inventors: Ravil A. Sitdikov, Eddie W. Adams, Magdalena A. Torrance, David K. Aley, Erik J. Smith, Victor C. Esch
  • Publication number: 20170038374
    Abstract: The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
    Type: Application
    Filed: October 24, 2016
    Publication date: February 9, 2017
    Inventors: Sergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov