Abstract: Post-implant modifications to an intraocular lens. In some embodiments the lens is an accommodating intraocular lens.

Abstract: A method for treating benign prostatic hyperplasia using a laser is provided. The method includes emitting, in proximity to prostatic tissue, laser light at a wavelength that is controlled to be within at least one of (i) a range between about 1275 nm and about 1475 nm or (ii) a range between about 1830 nm and about 2010 nm. The wavelength is selected to have a higher absorption by water than laser light at a wavelength of 830 nm and a lower absorption by hemoglobin than laser light at the wavelength of 830 nm. Emission of the laser light is controlled such that the prostatic tissue is heated to a temperature of less than about 100° C. to coagulate the prostatic tissue.

Abstract: Embodiments are described for a light-based dermal enhancing apparatus and methods of use. In general, the dermal enhancing apparatus includes elongated housing having opposite top and bottom ends. The housing has a translucent outer shell that defines a translucent window at the top end of the housing that is capable of permitting passage of light therethrough from one or more treatment light emitting diodes (LEDs) located in the housing. The housing may also include an inner shell that provides an interior cavity in which the interior components of the dermal enhancing apparatus are located. In addition to the treatment LEDs, a tube with a reflective lumen is located in the housing to afford a passage between the window and the LEDs. In some embodiments, the outer shell may have an elongated indicator guide that extends from the translucent window towards the bottom end of the housing so that refracted light from the light passing through the window illuminates the indicator guide.

Abstract: An accommodating intraocular lens is provided having optical parameters that are altered in-situ, wherein an optic portion of the lens includes a lens piston that alters the shape of a lens element of the lens to alter the optical power of the lens, responsive to forces applied to a haptic portion to the lens by contraction of the ciliary muscles. Forces applied to the haptic portion are concentrated by the lens piston to provide a greater dynamic range, and may be further augmented by the use of haptic pistons disposed in the haptic portion of the lens.

Abstract: A diagnostic system is disclosed. The diagnostic system comprises a sensing device having a retrieval wire. The sensing device is configured to collect data. The system also includes a deployable housing that has a body defining an interior and an exterior. The housing is configured to allow fluid to flow through the housing and the housing completely encloses the sensing device. The system also includes a disposer for disposing the housing into a body part. The system also includes a processing device configured to receive the data from the sensing device. The processing device is configured to transmit the data.

Abstract: A lens is provided that having optical parameters that may be adjusted in-situ, and is particularly useful as an IOL for use in cataract patients that require an adjustment in the optical power of the lens post-implantation. In one embodiment, the lens body carries an array of interior fluid-filled cells in which fluid is controllably moved upon application of energy from an external source to move a fluid media into or out of the cells to thereby alter the lens surface shape.

Abstract: A medical device is described that can be used to detect in stent restenosis. This invention consists of a stent of current or modified technology, an electromagnetic wave transmitter to excite the stent and an acoustic sensor to detect stent acoustic oscillations.

Abstract: A noninvasive medical device and diagnostic system is disclosed that can be used to determine the degree of viability, flow and stenosis of a graft within the human body. This invention incorporates a sensing element in or near an AV graft. As stenosis occurs within or near the graft, the change in pressure within the graft can be detected by the sensors and provide the physician with information about the location of the stenosis. This information can than be used to provide the best course of treatment for the patient.

Abstract: A medical device is described that can be used to detect in stent restenosis. This invention consists of a stent of current or modified technology, an electromagnetic wave transmitter to excite the stent and an acoustic sensor to detect stent acoustic oscillations.

Abstract: Methods and apparatus for creating fluid flow from one location to another are disclosed. The fluid flow is created via the absorption of repetitive pulses of radiation in a fluid to generate bubbles that expand and collapse repetitively. This fluid mechanism, or pumping phenomenon, can be used to aid removal of a total or partial occlusion in a body passage by disrupting a surface of the occlusion with acoustic shock and pressure waves and/or by causing mechanical disruption of the occlusive material. Appropriate selection of materials and particular constructions improve apparatus flexibility.

Abstract: The invention encompasses methods and flexible apparatus for creating fluid flow from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by disrupting the surface of the occlusion with acoustic shock and pressure waves and/or by causing mechanical disruption of the occlusive material. Flexibility is improved with choice of materials and particular constructions.

Abstract: The invention encompasses methods and apparatus for pumping fluid from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by emulsifying the occlusion with acoustic shock and pressure waves or by causing mechanically disrupting the occlusive material.

Abstract: The invention encompasses methods and flexible apparatus for creating fluid flow from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by disrupting the surface of the occlusion with acoustic shock and pressure waves and/or by causing mechanical disruption of the occlusive material. Flexibility is improved with choice of materials and particular constructions.

Abstract: The invention encompasses methods and flexible apparatus for delivering radiation energy to a radiation-absorbing fluid within the apparatus to generate a series of expanding and collapsing bubbles therein, and thereby generate flow in a fluid surrounding the apparatus. Effective fluid flow is obtained via at least one optical fiber, disposed within the apparatus near a distal opening therein, that, when fired, tends to pump fluid with respect to the apparatus, and at least one other optical fiber, disposed within the apparatus in the vicinity of a side opening thereof, that, when fired, tends to agitate fluid near its distal end. These pumping and agitative actions cause a net fluid motion that is particularly effective in disrupting a partial or total occlusion in a body passage, such as a blood vessel, within which the apparatus is operated.

Abstract: Partial or total occlusions of fluid passages within the human body are removed by positioning an array of optical fibers in the passage and directing treatment radiation pulses along the fibers, one at a time, to generate a shock wave and hydrodynamics flows that strike and emulsify the occlusions. A preferred application is the removal of blood clots (thrombin and embolic) from small cerebral vessels to reverse the effects of an ischemic stroke. The operating parameters and techniques are chosen to minimize the amount of heating of the fragile cerebral vessel walls occurring during this photo acoustic treatment. One such technique is the optical monitoring of the existence of hydrodynamics flow generating vapor bubbles when they are expected to occur and stopping the heat generating pulses propagated along an optical fiber that is not generating such bubbles.

Abstract: The invention encompasses methods and apparatus for pumping fluid from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by emulsifying the occlusion with acoustic shock and pressure waves or by causing mechanically disrupting the occlusive material.

Abstract: An apparatus, including a light detecting means, determines the actual position of an optical fiber array having one or more, but fewer than all, short fibers by detecting light transmitted through the short fiber(s) as a laser beam is horizontally and/or vertically scanned across the proximal fiber end(s). The fiber array is attached to an alignment block that facilitates delivery of the array to an accurate positioning means comprising two substantially parallel dowels.

Abstract: An apparatus and method for accurately and reproducibly locating a planar array of optical fibers in space are disclosed. A single acousto-optic modulator is used to accurately and substantially-simultaneously deflect multiple beams of different-wavelength radiation energy to each of said accurately-positioned optical fibers. Both aspects of the invention can be used in an apparatus and method for removing occlusions from vessels, as previously disclosed.

Abstract: Apparatus for pumping fluid from one location to another via generation of bubbles in fluid, and expansion and callapse thereof, are described. These apparatus deliver repetitive pulses of radiation to a fluid to form bubbles therein. The expansion and collapse of the bubbles cause fluid motion or pumping. This pumping can be used to facilitate removal of a total or partial occlusion in a body passage by a variety of mechanisms. The apparatus are flexible to facilitate use within a body passage.

Abstract: The invention encompasses methods and apparatus for pumping fluid from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by emulsifying the occlusion with acoustic shock and pressure waves or by mechanically disrupting the occlusive material.