Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

Abstract: This document provides materials and methods for treating pancreatitis (e.g., severe acute pancreatitis), a complication associated with pancreatitis (e.g., organ failure), and/or an acute inflammatory condition in a mammal (e.g., inflammation from a burn or trauma). For example, methods and materials for using one or more colipase inhibitors to treat a mammal having pancreatitis (e.g., acute pancreatitis) are provided.

Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

Abstract: This document provides materials and methods for treating pancreatitis (e.g., severe acute pancreatitis), a complication associated with pancreatitis (e.g., organ failure), and/or an acute inflammatory condition in a mammal (e.g., inflammation from a burn or trauma). For example, methods and materials for using one or more colipase inhibitors to treat a mammal having pancreatitis (e.g., acute pancreatitis) are provided.

Abstract: Techniques are described for aggregating code coverage data generated from various types of testing of software modules, and automatically determining whether to promote software upwards in a multi-level software deployment hierarchy based on the aggregated code coverage data. In embodiments, a code coverage metric is determined for a software module, and the metric is compared to a set of promotion criteria, including whether the metric meets a predetermined threshold for quality. In some cases, the threshold may be a general threshold, a threshold based on the level of possible promotion, and/or a threshold that is based on an identified category for the software module such as whether the module is a front-end module, a shared module, a legacy module, or a critical module.

Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

Abstract: In some implementations, a testing service receives a test execution request for executing test operations on a test target. The testing service may map the test execution request to a particular type of supported test framework from among a plurality of types of supported test frameworks. The testing service may obtain a test package provided by a user that requested the testing, such as from a cloud storage location. The testing service determines a computing capacity for executing the testing and appropriates a plurality of workers in a cloud computing service. The testing service configures the plurality of workers for executing the test operations based on at least one of the test framework, the test execution request or the test package. The testing service provides test execution chunks from the test package to the plurality of workers for executing the testing on the test target.

Abstract: Techniques are described for aggregating code coverage data generated from various types of testing of software modules, and automatically determining whether to promote software upwards in a multi-level software deployment hierarchy based on the aggregated code coverage data. In embodiments, a code coverage metric is determined for a software module, and the metric is compared to a set of promotion criteria, including whether the metric meets a predetermined threshold for quality. In some cases, the threshold may be a general threshold, a threshold based on the level of possible promotion, and/or a threshold that is based on an identified category for the software module such as whether the module is a front-end module, a shared module, a legacy module, or a critical module.

Abstract: Techniques are described for aggregating code coverage data generated from various types of testing of software modules, and automatically determining whether to promote software upwards in a multi-level software deployment hierarchy based on the aggregated code coverage data. In embodiments, a code coverage metric is determined for a software module, and the metric is compared to a set of promotion criteria, including whether the metric meets a predetermined threshold for quality. In some cases, the threshold may be a general threshold, a threshold based on the level of possible promotion, and/or a threshold that is based on an identified category for the software module such as whether the module is a front-end module, a shared module, a legacy module, or a critical module.

Abstract: Materials and Methods for producing localized hypothermia in a patient for treatment of a weight disorder (e.g., obesity).

Abstract: In some implementations, a testing service receives a test execution request for executing test operations on a test target. The testing service may map the test execution request to a particular type of supported test framework from among a plurality of types of supported test frameworks. The testing service may obtain a test package provided by a user that requested the testing, such as from a cloud storage location. The testing service determines a computing capacity for executing the testing and appropriates a plurality of workers in a cloud computing service. The testing service configures the plurality of workers for executing the test operations based on at least one of the test framework, the test execution request or the test package. The testing service provides test execution chunks from the test package to the plurality of workers for executing the testing on the test target.

Abstract: In some implementations, a testing service receives a test execution request for executing test operations on a test target. The testing service may map the test execution request to a particular type of supported test framework from among a plurality of types of supported test frameworks. The testing service may obtain a test package provided by a user that requested the testing, such as from a cloud storage location. The testing service determines a computing capacity for executing the testing and appropriates a plurality of workers in a cloud computing service. The testing service configures the plurality of workers for executing the test operations based on at least one of the test framework, the test execution request or the test package. The testing service provides test execution chunks from the test package to the plurality of workers for executing the testing on the test target.

Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).

Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).