Abstract: Disclosed herein is a process for the manufacture of mirtazapine and intermediates useful in preparing mirtazapine which includes the reduction of 1-(3-carboxypyridyl-2)-4-methyl-2-phenylpiperazine with an organoaluminum hydride.

Abstract: Novel blood-brain barrier permeant amyloid-targeting peptides and peptide conjugates are described. The peptide conjugates include a radioisotope or other label in a stable complex that translocates across brain capillary endothelial cell monolayers. The labeled peptide conjugate binds to amyloid plaques (A?) associated with Alzheimer's disease, and is useful for the targeted delivery of therapeutic and diagnostic molecules into the brain.

Abstract: Compositions comprising nitrosyl-cobinamide are provided. Also provided are methods for treating hypertension, which comprise administering therapeutically effective amounts of nitrosyl-cobinamide. Also provided are methods for producing nitrosyl-cobinamide.

Abstract: The present invention is a kit and method and device for the preparation of a kit for detecting Human Cytomegalovirus (hCMV) in which the amplimers are transcripts of a glycoprotein B neutralization-related epitope gene of hCMV. The amplicons are hybridized to a specific oligonucleotide probe, which allows the amplicons to be detected.

Abstract: Novel blood-brain barrier permeant amyloid-targeting peptides and peptide conjugates are described. The peptide conjugates include a radioisotope or other label in a stable complex that translocates across brain capillary endothelial cell monolayers. The labeled peptide conjugate binds to amyloid plaques (A?) associated with Alzheimer's disease, and is useful for the targeted delivery of therapeutic and diagnostic molecules into the brain.

Abstract: There is provided a method and kit for rapid clinical diagnosis of HCV in which the amplimers are transcripts of a polyprotein gene of HCV. The amplicons are hybridized to a specific oligonucleotide probe, which allows the amplicons to be detected.

Abstract: The method and apparatus of the present invention discloses a communications server that may be simultaneously connected to and conversant with a plurality of wire-lined and wireless networks. The communications server of the present invention includes, among other things, a central processing unit, a network interface unit, and a memory to direct the operations of the server in such a way that communications sessions may be established between one or more users and one or more of the plurality of wire-lined or wireless networks. In a preferred embodiment, the communications sessions may be transacted between a variety of communication devices including a multi-mode wireless phone which identifies itself to the communications server and indicates to the communication server which of the plurality of wire-lined or wireless networks is to be used for a particular communications session.

Abstract: The method and apparatus of the present invention enable the use of a single wireless mobile user communications device to transact communications sessions using a plurality of communication modes, both wireless and wire-lined. The single wireless mobile user communications device is comprised of a reduced instruction set processing unit, a digital signal processor unit, a novel multi-mode tunable transceiver, and a memory to direct operation of the communications device in such a way that the transceiver continuously samples a plurality of wireless communication modes, and upon receiving a request to establish a communications session, selects the one of the plurality of communication modes having the optimum signal characteristics as the transaction medium for that particular communications session.

Abstract: There is provided a method and kit for rapid clinical diagnosis of HBV in which the amplimers are transcripts of a pre-core or envelop region gene of HBV. The amplicons are hybridized to a specific oligonucleotide probe, which allows the amplicons to be detected.

Abstract: A method and apparatus for combining a control signal and a video signal on a standard video cable is disclosed. The video cable is connected to a display monitor in order to provide access and control functions to the monitor. In a particular implementation, a USB signal is transmitted with a digital video signal across a standard digital video connector.

Abstract: There is provided a method and kit for rapid clinical diagnosis of HBV in which the amplimers are transcripts of a pre-core or envelop region gene of HBV. The amplicons are hybridized to a specific oligonucleotide probe, which allows the amplicons to be detected.

Abstract: A method and apparatus that extends the video graphics bus from the computer unit to a monitor is used within a computer system that includes a computer unit and a monitor. The computer unit includes a central processing unit, system memory, an accelerated graphics port chip set, and a first AGP coupling converter. The first AGP coupling converter is operably coupled to the AGP chip set and receives video graphics data (e.g., vertex data for triangles corresponding to three-dimensional graphics) and converts the transport formatting of the video graphics. Such transport formatting conversion may include changing from a parallel transport to a serial transport or from a parallel transport to a reduced parallel transport. The monitor includes a second AGP coupling converter, a video graphics controller, and a display device. The second AGP coupling converter is operably coupled, via a cable, to the first AGP coupling converter.

Abstract: There is provided a method and kit for rapid clinical diagnosis of HCV in which the amplimers are transcripts of a polyprotein gene of HCV. The amplicons are hybridized to a specific oligonucleotide probe, which allows the amplicons to be detected.

Abstract: The present invention is a method and kit for rapid clinical diagnosis of hCMV in which the amplimers are transcripts of a glycoprotein B neutralization-related epitope gene of hCMV. The amplicons are hybridized to a specific oligonucleotide probe, which allows the amplicons to be detected.