Abstract: A surface enhanced luminescence (SEL) sensor may include a substrate and nano fingers extending from the substrate. In one implementation, the nano fingers may be arranged in a cluster of at least three nano fingers extending from the substrate. The nano fingers of the cluster having different geometries so as to bend into a closed state such that each of the nano fingers of the cluster are linked to one another.

Abstract: A fluid entrained particle separator may include an inlet passage to direct particles entrained in a fluid, a first separation passage branching from the inlet passage, a second separation passage branching from the inlet passage and electrodes to create electric field exerting a dielectrophoretic force on the particles to direct the particles to the first separation passage or the second separation passage, wherein the first separation passage, the second separation passage, the electric field and the dielectrophoretic force extend in a plane.

Abstract: In example implementations, an apparatus is provided. The apparatus includes a microfluidic channel to receive a fluid containing a plurality of different cells. A dielectrophoresis (DEP) separator in the apparatus separates the plurality of different cells passing through DEP separator within the microfluidic channel. In addition, the apparatus includes a density separator to further separate a portion of the plurality of different cells from the DEP separator based on a density of each one of the plurality of different cells.

Abstract: A sample preparation system includes a sample input, a first chamber fluidly coupled to the sample input and containing a sample preparation reagent, a second chamber containing a surface enhanced Raman spectroscopy (SERS) sensor structure and a third chamber containing a sensor preparation solution. The sample input, the first chamber and the second chamber are fluidly coupled to one another in a series and the third chamber is fluidly coupled to the third chamber outside of the series so as to sequentially direct a sample received by the sample input through the first chamber to the second chamber and out of the second chamber and so as to direct the sensor preparation solution into the second chamber following discharge of the sample out of the second chamber.

Abstract: Techniques for separating particles of interest from whole blood are disclosed. An example particle separation chip includes a first inlet on the particle separation chip for receiving whole blood and a second inlet on the particle separation chip for receiving a lysis buffer. The particle separation chip also includes a mixer to mix the whole blood with the lysis buffer to provide lysis of red blood cells in the whole blood. The particle separation chip also includes a buffer exchanger to exchange the lysis buffer for a dielectrophoresis buffer to produce a solution that enables dielectrophoretic separation of particles of interest. The particle separation chip also includes a separator coupled to an output of the buffer exchanger to separate the particles of interest from other particles in the solution via dielectrophoretic separation and deliver the particles of interest to an outlet on the particle separation chip.

Abstract: A microfluidic device may, in an example, include at least one microfluidic channel, a dielectrophoresis separator to separate a plurality of cells passing within the at least one microfluidic channel, and a thermal resistor to eject at least one cell from the microfluidic device. A cassette may, in an example, include a die coupled to a substrate of the cassette, the die including at least one microfluidic channel, a dielectrophoresis separator along the microfluidic channel to separate a plurality of cells passing within the microfluidic channel, and an ejection device to eject at least one of the plurality of cells into an assay well.

Abstract: A channel layer of a digital microfluidic device may include a number of sample wells located on a first side of the die, a number of first capillary channels fluidically coupled to each of the sample wells, the first capillary channels drawing a fluid from the sample wells using capillary forces, a capillary break fluidically coupled to each of the first capillary channels to dispense a portion of the fluid drawn from the sample wells through the capillary forces, a number of intermediate chambers fluidically coupled to the capillary break, a number of second capillary channels fluidically coupled to the intermediate chambers, the second capillary channels drawing the fluid from the intermediate chambers using capillary forces, and a number of mixing chambers fluidically coupled to the second capillary channels into which the capillary forces of the second capillary channels cause the fluid to enter the mixing chambers.

Abstract: A surface enhanced luminescence (SELS) sensor may include a substrate and nano fingers projecting from the substrate. Each of the nano fingers may include a polymer pillar having a sidewall and a top, a coating layer covering the sidewall and a metal cap supported by and in contact with the top of the pillar.

Abstract: A surface enhanced Raman scattering (SERS) sensor may include a substrate, an electrically conductive layer having a first portion spaced from a second portion by a gap, an electrically resistive layer in contact with and extending between the first portion and the second portion of the electrically conductive layer to form an electrically resistive bridge across the gap that heats the nano fingers in response to electrical current flowing across the bridge from the first portion to the second portion and nano fingers extending upward from the bridge.

Abstract: A microfluidic pressure sensor may include a reference chamber, a sensed volume, a microfluidic channel connecting an interior of the reference chamber to an interior of the sensed volume, a volume of liquid contained and movable within the microfluidic channel while occluding the microfluidic channel and a sensor to output signals indicating positioning of the volume of liquid along the microfluidic channel. Positioning of the volume of liquid along microfluidic channel indicates a pressure of the sensed volume.

Abstract: A microfluidic device may include a microfluidic channel including an electrode placed at opposite ends of the microfluidic channel to create an electrical field within the channel and an ejection device to eject at least one cell porated within the electrical field. A cassette may include a substrate, a die coupled to the substrate, a microfluidic channel defined within the die, the microfluidic channel including a necked portion to receive a cell therein and at least two electrodes each placed at a first and a second end of the microfluidic channel to apply an electric field to the cell above a proration threshold and a cell ejection device to eject the cell from the die.

Abstract: In one example in accordance with the present disclosure, a cellular analytic system is described. The cellular analytic system includes a series of analytic devices. Each analytic device includes 1) a separator to separate a cellular particle from a surrounding fluid, 2) an analyzer coupled to a first outlet of the separator to analyze the surrounding fluid, and 3) at least one lysing device coupled to at least a second outlet of the separator to rupture a membrane of the cellular particle. An outlet of the lysing device is fluidly coupled to a separator of a downstream analytic device.

Abstract: An example system includes a well plate having at least one well, an array of electrodes positioned on a surface of a bottom floor of the well, and a controller to direct electrical voltage to the electrodes to generate a non-uniform electrical field. The electrical field is to direct an object in the electrical field to a target position in the well.

Abstract: A fluid dispenser may include a fluid ejector to eject fluid in a direction and a capillary pick up to wick fluid to the fluid ejector with capillary action. The capillary pick up may project beyond the fluid ejector in the direction.

Abstract: An object focuser may include a substrate, a sample fluid passage supported by the substrate, a first inertial pump supported by the substrate to pump a sample fluid entraining an object through the sample fluid passage, a first sheath fluid passage, a second inertial pump supported by the substrate to pump a first sheath fluid through the first sheath fluid passage, a second sheath fluid passage and a second inertial pump supported by the substrate to pump a second sheath fluid through the second sheath fluid passage. The first sheath fluid passage and the second sheath fluid passage are connected to the sample fluid passage at a convergence on opposite sides of the sample fluid passage.

Abstract: An example system includes an input channel to flow nucleic segments therethrough, a mixing portion coupled to the input channel, a separation chamber in fluid communication with the second end of the input channel, at least two output channels coupled to the chamber, and an integrated pump to facilitate flow through the separation chamber. The mixing portion is to include at least two different categories of beads having different sizes from each other and having a probe to attach to a corresponding nucleic acid segment. The separation chamber has a passive separation structure including an array of columns spaced apart to facilitate separation of the different categories of beads and attached corresponding nucleic acid segment into at least two flow paths based on a size of the category of the beads. Each output channel is to receive separated categories of beads and attached nucleic acid segments.

Abstract: A chromatography-surface enhanced luminescence (SEL) sensing system may include a chromatography subsystem to separate a sample into eluate fractions having different elution times, an SEL stage and an eluate fraction dispenser. The eluate fraction dispenser is to direct different eluate fractions onto distinct regions of the SEL stage based upon the different elution times.

Abstract: An apparatus may include a lower chamber to contain a culture that emits volatile organic compounds, an upper chamber, a first sensor within the upper chamber, a second sensor within the upper chamber in a transport selector. The second sensor may be different than the first sensor so as to sense volatile organic compounds differently than the first sensor. The transport selector is to transport a selected portion of the volatile organic compounds emitted from the lower chamber to the first sensor and a second portion of the volatile organic compounds emitted from the lower chamber to the second sensor.

Abstract: A three-dimensional object modeling method may include applying a nonrotating nonuniform electric field to apply a dielectrophoretic torque to a three-dimensional object to rotate the three-dimensional object, capturing images of the object at different angles during rotation of the object and forming a three-dimensional model of the object based on the captured images.

Abstract: The present disclosure is drawn to a photoacoustic explosives detector, including a sample chamber, an aerosolizing ejector, a light source, and a pressure differential sensor. The sample chamber can include a photoreaction region, and the aerosolizing ejector can be positioned to eject 3 pL to 10 nL droplets of a liquid sample into the photoreaction region. A light source can be directed to emit focused light through the photoreaction region, and a pressure differential sensor can be positioned with respect to the photoreaction region to sense degradation of the droplets exposed to the focused light.