Abstract: Contamination of environment by a multitude of pollutants is becoming a global health concern. Lot of methods are being used for bioremediation of those pollutants. A method and system for one or more pollutants has been provided. The sample is collected from a site containing pollutants. Pollutants are then isolated from the sample. Further, a knowledgebase various types of degraders of those pollutant is created. Using this knowledgebase a map of microbes is created. The map of microbes is then used to design a first microbial consortia and a second microbial consortia which together contributes genes, proteins and enzymes required for degradation of the pollutants. And finally, a concoction of the first and/or second microbial consortia is administered on the site. The method further comprises the checking the efficacy of the administered consortia and further comprise re-administration of the concoction.

Abstract: Devices and methods for performing shear-assisted extrusion processes for forming extrusions of a desired composition from a feedstock material are provided. The processes can use a device having a scroll face having an inner diameter portion bounded by an outer diameter portion, and a member extending from the inner diameter portion beyond a surface of the outer diameter portion. Extrusion feedstocks and extrusion processes are provided for forming extrusions of a desired composition from a feedstock. The processes can include providing a feedstock having at least two different materials and engaging the materials with one another within a feedstock container. Methods for preparing metal sheets are provided that can include preparing a metal tube via shear assisted processing and extrusion; opening the metal tube to form a sheet having a first thickness; and rolling the sheet to a second thickness that is less than the first thickness.

Abstract: Introduced here are approaches to determining causal relationships in mixed datasets containing data related to continuous variables and discrete variables. To accomplish this, a marketing insight and intelligence platform may employ a multi-phase approach in which dependency is established before the data related to continuous variables is discretized. Such an approach ensures that information regarding dependence is not lost through discretization.

Abstract: Methods, systems, and non-transitory computer readable storage media are disclosed for utilizing enhanced curve primitives to modify color gradients in vector-based graphics. To illustrate, the disclosed system can receive an input of a curve to insert into a portion of a vector-based graphic including a mesh for a color gradient. The disclosed system can then insert a discontinuity into the mesh by adding a plurality of vertices to the mesh defining two unconnected edges at the position of the curve within the portion of the vector-based graphic. After inserting the discontinuity into the mesh, the disclosed system can determine colors for the edges of the discontinuity based on one or more user-selected colors and/or one or more colors associated with the color gradient. The disclosed system can then update the color gradient in response to determining the colors for the edges of the discontinuity.

Abstract: Disclosed herein is a DC-AC converter, in accordance with some embodiments. Accordingly, the DC-AC converter comprises a transformer, a pulse generator, a pulse modulator, a switching element, and an analog low pass filtering stage. Further, the pulse generator is configured for generating pulses characterized by a pulse frequency. Further, the pulse modulator is configured for generating a pulse density modulated signal based on modulating the pulses using a sine wave signal of a fundamental frequency. Further, the switching element is connected in series with a primary winding of the transformer. Further, the switching element is configured to be switched between an on state and an off state based on the pulse density modulated signal. Further, the analog low pass filtering stage is configured for generating an AC voltage of the fundamental frequency based on attenuating higher frequency components of an unfiltered AC voltage at a secondary winding of the transformer.

Abstract: This disclosure involves applying an edit to objects in a vector design corresponding to a selected level of an object hierarchy. A system accesses a vector design comprising first, second, and third objects, each of the objects having a respective axis coordinate. The system assigns the first object and the second object to or within a common level in an object hierarchy based on determining that a similarity score comparing the two objects exceeds a threshold and that a modification causing the axis coordinates of the two objects to be adjacent maintains an overlap between the third object and the two objects. The system receives a user input selecting the first object and expands the selection to the second object based on the second object being assigned to the common level. The system applies an edit to the first and second objects based on the expansion of the selection.

Abstract: Photoactive compounds are disclosed. The disclosed compounds can exhibit molecular structural elements tending to increase the evaporability of the compounds, such as by including geometric core disruption by use of conformationally restricted side groups instead of freely rotatable side groups or use of indandione moieties instead of dicyanomethyleneindanone moieties. The disclosed photoactive compounds include those with an imine-bridging linking moiety, which can shift the optical properties to a more red-shifted absorbance as compared to compounds with an alkene-bridging linking moiety. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: Systems and methods for increasing the efficiency of inverters are provided. In some embodiments, an inverter may be configured to connect to a direct current power source and output alternating current power. The inverter may include one or more transistors configured to receive a direct current signal and output a pulse width modulated signal having a particular switching frequency or spread spectrum frequencies. The inverter also includes a low pass filter having multiple elements where each of the multiple elements have parasitic characteristics. One or more of the multiple elements may be designed such that the frequency response has a notch or a minimum at the switching frequency while having a desired cutoff frequency.

Abstract: Photoactive compounds are disclosed. The disclosed compounds can exhibit molecular structural elements tending to increase the evaporability of the compounds, such as by including geometric core disruption by use of conformationally restricted side groups instead of freely rotatable side groups or use of indandione moieties instead of dicyanomethyleneindanone moieties. The disclosed photoactive compounds include those with an imine-bridging linking moiety, which can shift the optical properties to a more red-shifted absorbance as compared to compounds with an alkene-bridging linking moiety. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: Photoactive compounds are disclosed. The disclosed compounds can exhibit molecular structural elements tending to increase the evaporability of the compounds, such as by including geometric core disruption by use of conformationally restricted side groups instead of freely rotatable side groups or use of indandione moieties instead of dicyanomethyleneindanone moieties. The disclosed photoactive compounds include those with an imine-bridging linking moiety, which can shift the optical properties to a more red-shifted absorbance as compared to compounds with an alkene-bridging linking moiety. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: There are provided, inter alia, methods for treatment of cancer. The methods include means of identifying the NAD biosynthetic pathway on which depend cancer cells in a tumor, in a subject suffering from cancer. The methods further include administering to a subject in need a therapeutically effective amount of an inhibitor of the NMRK1 enzyme pathway to a tumor where the cancer cells are dependent of the NAD salvage pathway, allowing to lower the of dose FK866 administered to the subject. The methods also include administering to a subject in need a therapeutically effective amount of a bacterial inhibitor of NADSYN1 to a tumor where the cancer cells depend on the Preiss Handler pathway.

Abstract: An intelligent data ingestion and governance method and system is disclosed. A set of data requirements is received from a user. The set of data requirements includes multiple different formats and corresponding location information indicating a plurality of corresponding different data sources. One or more data policies are also received from the user as part of the set of data requirements. A configuration file is automatically generated using the set of data requirements. A new dataset is retrieved from the plurality of corresponding different sources of data, using the generated configuration file. The retrieved dataset is classified, and metadata for the retrieved dataset is provided. Actionable policies are automatically generated using the metadata and the user defined data policies, and a compliance engine is generated. Security of access to the retrieved input data is controlled using the generated compliance engine.

Abstract: Embodiments of the present invention relate to 6-6 bicyclic aromatic ring substituted nucleoside analogues, including, for example, the following compound: Embodiments of the present invention also relate to uses of the disclosed compounds for the inhibition of protein arginine methyltransferase 5 (PRMT5).

Abstract: A multi-layer light source includes an emissive layer and a textured lighting gel layer, the lighting gel layer being situated between the emissive layer and a 2D canvas or a 3D object. User inputs controlling the multi-layer light source are received, these user inputs being provided with the user interacting with the 2D canvas without switching to editing in 3D space. The multi-layer light source is configured based on the user inputs and, based on the configuration, emission of light rays from the multi-layer light source is determined. Areas of shadows cast by 3D objects are also determined. An image generation system determines, a color of a location (e.g., a pixel) on the 2D canvas or the 3D object that a light ray intersects based on the color that is in the lighting gel layer that the light ray passes through.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for efficiently and flexibly extracting reusable geometric assets from an arbitrary arrangement of vector geometry within a digital image. For example, the disclosed systems can organize vector geometry of a digital image by structuring geometric objects into groups (e.g., clusters). The disclosed systems can assign mnemonics to these groups and transform the digital image into a mnemonic sequence. Moreover, the disclosed systems can utilize various computer-implemented algorithms to identify and filter patterns within the mnemonic sequence. The disclosed systems can then generate pattern scores for these patterns and identify which patterns of geometric objects to include within a set of reusable geometric assets.

Abstract: A device implementing an inter-device credential transfer system may include at least one processor that is configured to receive a request to transfer a transaction credential from a first device to a second device, the transaction credential being associated with a stored monetary value and the request comprising a transaction credential identifier of the transaction credential. The at least one processor is further configured to prevent, responsive to the request, the transaction credential from being utilized for payment transactions by the first device. The at least one processor is further configured to provision an instance of the transaction credential on the second device. The at least one processor is further configured to cause the instance of the transaction credential to be activated on the second device with a balance corresponding to the stored monetary value associated with the transaction credential.

Abstract: Techniques for prefetching operation cost based digital content and digital content with emphasis that overcome the challenges of conventional systems are described. In one example, a computing device may receive digital content representations of digital content from a service provider system, which are displayed on a user interface of the computing device. Thereafter, the computing device may also receive digital content as prefetches having a changed display characteristic as emphasizing a portion of the digital content based on a model trained using machine learning. Alternatively, the computing device may receive digital content as a prefetch based on a model trained using machine learning in which the model addresses a likelihood of conversion of a good or service and an operation cost of providing the digital content. Upon receiving a user input selecting one of the digital content representations, digital content is rendered in the user interface of the computing device.

Abstract: A multi-layer light source includes an emissive layer and a textured lighting gel layer, the lighting gel layer being situated between the emissive layer and a 2D canvas or a 3D object. User inputs controlling the multi-layer light source are received, these user inputs being provided with the user interacting with the 2D canvas without switching to editing in 3D space. The multi-layer light source is configured based on the user inputs and, based on the configuration, emission of light rays from the multi-layer light source is determined. Areas of shadows cast by 3D objects are also determined. An image generation system determines, a color of a location (e.g., a pixel) on the 2D canvas or the 3D object that a light ray intersects based on the color that is in the lighting gel layer that the light ray passes through.

Abstract: Techniques for providing and servicing listed repository items such as algorithms, data, models, pipelines, and/or notebooks are described. In some examples, web services provider receives a request for a listed repository item from a requester, the request indicating at least a category of the repository item and each listing of a repository item includes an indication of a category that the listed repository item belongs to and a storage location of the listed repository item, determines a suggestion of at least one listed repository item based on the request, and provides the suggestion of the at least one listed repository item to the requester.

Abstract: One or more processors generate a view that identifies the data records of a first database having a back-level version. Instructions are received to migrate the data records from a back-level version to a new version of the data records. Responsive to receiving a query requesting data records of the first database, the version level of the requested data records is determined based on the generated view. Responsive to determining the requested data records are in the back-level version, a migration is performed on the requested data records including changes resulting in the new version of the requested data records. The requested data records are identified as changed to the new version of data records, and the new version of the requested data records are written to a pre-determined storage location and are provided to a requestor submitting the query.