Patents by Inventor Virendra Kumar

Virendra Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Publication number: 20020103164
    Abstract: Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided.
    Type: Application
    Filed: March 13, 2001
    Publication date: August 1, 2002
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Anthony Michael Marella, Virendra Kumar, Forrest Gaul, Deqi Guo
  • Kappa agonist compounds and pharmaceutical formulations thereof
    Patent number: 6391910
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formulae I, II, IIA, III, IIIA, IV and IVA have the structure: wherein R1, R2, R3, R4; and X, X4, X5, X7, X9; Y, Z and n are as described in the specification.
    Type: Grant
    Filed: January 6, 2000
    Date of Patent: May 21, 2002
    Assignee: Adolor Corporation
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Michael Anthony Marella, Virendra Kumar, Forrest Gaul, An-Chih Chang, Deqi Guo
  • Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Publication number: 20020042399
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and 5 method of using them as analgesics and pruritic agents are provided.
    Type: Application
    Filed: January 26, 2001
    Publication date: April 11, 2002
    Applicant: Adolor Corporation
    Inventors: Lawrence I. Kruse, An-Chih Chang, Diane L. DeHaven-Hudkins, John J. Farrar, Forrest Gaul, Virendra Kumar, Michael Anthony Marella, Alan L. Maycock, Wei Yuan Zhang
  • Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Publication number: 20020013296
    Abstract: Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided.
    Type: Application
    Filed: March 13, 2001
    Publication date: January 31, 2002
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Michael Anthony Marella, Virendra Kumar, Forrest Gaul, Deqi Guo
  • Kappa agonist compounds and pharmaceutical formulations thereof
    Patent number: 6303611
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formula having the structure: wherein R1, R2, and X Y, Z, Ar and n are as described in the specification.
    Type: Grant
    Filed: September 9, 1998
    Date of Patent: October 16, 2001
    Assignee: Adolor Corporation
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Michael Anthony Marella, Virendra Kumar, Forrest Gaul, An-Chih Chang, Deqi Guo
  • System for implementing a design for six sigma process
    Patent number: 6253115
    Abstract: A system for implementing a design for six sigma process having a plurality of sub-processes each having a plurality of sub-steps. The system includes an independent main application for implementing the design for six sigma process. A series of independent sub-process applications each implements one sub-process of the design for six sigma process. A tool library containing a plurality of executable tools is accessible by the main application and sub-process applications to access and execute the plurality of executable tools. A communications path interconnects the main application, the sub-process applications, and the tool library.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: June 26, 2001
    Assignee: General Electric Company
    Inventors: Arlie Russell Martin, Ahmed Elasser, Mohamed Ahmed Ali, Virendra Kumar, Jan Henning Aase, Brian Eric Lindholm, Mark Andrew Kolb
  • Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Patent number: 6239154
    Abstract: Method for the prevention or treatment of pruritis by administering to a patient an antipruritic compound, or pharmaceutically acceptable salt thereof, of the class arylacetamide, which is exemplified by compounds of the formulae I, II, IIA, III, IV and IVA having the structures: and in which R1-4, X, X4, X5, X7, X9, Y and Z are as described in the specification.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: May 29, 2001
    Assignee: Adolor Corporation
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Michael Anthony Marella, Virendra Kumar, Forrest Gaul, Deqi Guo
  • Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Patent number: 6180623
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and methods of using them as analgesics and anti-pruritic agents are provided. The compounds of formula IV have the structure: wherein X9; R1, R2, R3, R4; and n are as described in the specification.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: January 30, 2001
    Assignee: Adolor Corporation
    Inventors: Lawrence I. Kruse, An-Chih Chang, Diane L. DeHaven-Hudkins, John J. Farrar, Forrest Gaul, Virendra Kumar, Michael Anthony Marella, Alan L. Maycock, Wei Yuan Zhang
  • Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith
    Patent number: 6156769
    Abstract: Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.
    Type: Grant
    Filed: January 20, 2000
    Date of Patent: December 5, 2000
    Assignee: Apolor Corp.
    Inventors: John J. Farrar, An-Chih Chang, Virendra Kumar, Wei Yuan Zhang, Alan Cowan
  • Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Patent number: 6057323
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided.The compound of formula I, having the structure: ##STR1## wherein R.sub.1, R.sub.2 ;X; and ArY, Z and n are as described in the specification.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: May 2, 2000
    Assignee: Adolor Corporation
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Michael Anthony Marella, Virendra Kumar, Forrest Gaul, An-Chih Chang, Deqi Guo
  • Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritis therewith
    Patent number: 6054445
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compound of formulae IIA, having the structure: ##STR1## wherein R.sub.1, R.sub.2 ;X.sub.4, X.sub.5 ; andAr and n are as described in the specification.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: April 25, 2000
    Assignee: Adolor Corporation
    Inventors: Wei Yuan Zhang, Alan L. Maycock, Michael Anthony Marella, Virendra Kumar, Forrest Gaul, An-Chih Chang, Deqi Guo
  • Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith
    Patent number: 6048860
    Abstract: Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: April 11, 2000
    Assignee: Adolor Corporation
    Inventors: John J. Farrar, An-Chih Chang, Virendra Kumar, Wei Yuan Zhang, Alan Cowan
  • Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Patent number: 6028063
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided.The compounds of formula III having the structure: ##STR1## wherein Ar and X.sup.7 ;R.sub.1 and R.sub.2 ; andn are as described in the specification.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: February 22, 2000
    Assignee: Adolor Corporation
    Inventors: Lawrence I. Kruse, An-Chih Chang, Diane L. DeHaven-Hudkins, John J. Farrar, Forrest Gaul, Virendra Kumar, Michael Anthony Marella, Alan L. Maycock, Wei Yuan Zhang
  • Substituted N-arylmethyl and heterocylylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines and compositions and methods of use thereof
    Patent number: 6008226
    Abstract: Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines, pharmaceutical compositions containing them and methods for a) effecting c-GMP-phosphodiesterase inhibition, b) treating heart failure and/or hypertension, c) reversing or reducing nitrate-induced tolerance and d) treating angina pectoris, congestive heart disease and myocardial infarction utilizing them.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: December 28, 1999
    Assignee: Sanofi-Synthelabo
    Inventors: Virendra Kumar, John Alan Dority, Jr.
  • Kappa agonist anti-pruritic pharmaceutical formulaitons and method of treating pruritus therewith
    Patent number: 6004964
    Abstract: Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: December 21, 1999
    Assignee: Adolor Corporation
    Inventors: John J. Farrar, An-Chih Chang, Virendra Kumar, Wei Yuan Zhang, Alan Cowan
  • Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
    Patent number: 5981513
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compounds of formula II having the structure: ##STR1## wherein X.sub.4, X.sub.5 ;R.sub.1, R.sub.2 ; andAr and n are as described in the specification.
    Type: Grant
    Filed: March 21, 1998
    Date of Patent: November 9, 1999
    Assignee: Adolor Corporation
    Inventors: Lawrence I. Kruse, An-Chih Chang, Diane L. DeHaven-Hudkins, John J. Farrar, Forrest Gaul, Virendra Kumar, Michael Anthony Marella, Alan L. Maycock, Wei Yuan Zhang
  • Kappa agonist compounds and pharmaceutical formulations thereof
    Patent number: 5945443
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compound of formulae IV having the structure: ##STR1## wherein X.sub.9 ;R.sub.1, R.sub.2, R.sub.3, R.sub.4 ;and n are as described in the specification.
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: August 31, 1999
    Assignee: Adolor Corporation
    Inventors: Lawrence I. Kruse, An-Chih Chang, Diane L. DeHaven-Hudkins, John J. Farrar, Forrest Gaul, Virendra Kumar, Michael Anthony Marella, Alan L. Maycock, Wei Yuan Zhang
  • Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic and pruritic conditions therewith
    Patent number: 5888494
    Abstract: Topical film-forming compositions for the prevention and treatment of prutitus containing an opiate that is substantially devoid of central nervous system effects.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: March 30, 1999
    Assignee: Adolor Corporation
    Inventors: John J. Farrar, Alan L. Maycock, Virendra Kumar, Imre Jim Balogh
  • Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith
    Patent number: 5869521
    Abstract: Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: February 9, 1999
    Assignee: Adolor Corporation
    Inventors: John J. Farrar, An-Chih Chang, Virendra Kumar, Wei Yuan Zhang, Alan Cowan
  • 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
    Patent number: 5856349
    Abstract: 4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: January 5, 1999
    Assignee: Sanofi
    Inventors: Richard Paul Dunlap, Dennis John Hlasta, Ranjit Chimanlal Desai, Lee Hamilton Latimer, Chakrapani Subramanyam, John Joseph Court, Malcolm Rice Bell, Virendra Kumar