Patents by Inventor Vladislav B. Bergo

Vladislav B. Bergo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10451631
    Abstract: Microarray compositions suitable for analysis by one or several spectrographic methods are disclosed. In an embodiment, a microarray composition includes a three-dimensional solid support and a plurality of reactive microbeads positioned on the solid support in spatially distinct and addressable locations.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: October 22, 2019
    Inventor: Vladislav B. Bergo
  • Publication number: 20190072546
    Abstract: Bead arrays suitable for analysis by mass spectrometry are disclosed. In an embodiment, a bead array includes multiple reactive sites, each of the reactive sites being capable of binding multiple distinct target analytes.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 7, 2019
    Inventor: Vladislav B. Bergo
  • Publication number: 20190004038
    Abstract: Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
    Type: Application
    Filed: July 10, 2018
    Publication date: January 3, 2019
    Inventors: Mark J. Lim, Vladislav B. Bergo, Kenneth J. Rothschild
  • Patent number: 10101336
    Abstract: Microarray compositions suitable for analysis by one or several spectrographic methods are disclosed. In an embodiment, a microarray composition includes a three-dimensional solid support and a plurality of reactive microbeads positioned on the solid support in spatially distinct and addressable locations.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: October 16, 2018
    Inventor: Vladislav B. Bergo
  • Patent number: 10060912
    Abstract: Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: August 28, 2018
    Assignee: AmberGen, Inc.
    Inventors: Mark J Lim, Vladislav B Bergo, Kenneth J Rothschild
  • Publication number: 20170219601
    Abstract: Microarray compositions suitable for analysis by one or several spectrographic methods are disclosed. In an embodiment, a microarray composition includes a three-dimensional solid support and a plurality of reactive microbeads positioned on the solid support in spatially distinct and addressable locations.
    Type: Application
    Filed: April 13, 2017
    Publication date: August 3, 2017
    Inventor: Vladislav B. Bergo
  • Publication number: 20170176453
    Abstract: Microarray compositions suitable for analysis by one or several spectrographic methods are disclosed. In an embodiment, a microarray composition includes a three-dimensional solid support and a plurality of reactive microbeads positioned on the solid support in spatially distinct and addressable locations.
    Type: Application
    Filed: February 23, 2017
    Publication date: June 22, 2017
    Inventor: Vladislav B. Bergo
  • Patent number: 9618520
    Abstract: Microarray compositions suitable for analysis by one or several spectrographic methods are disclosed. In an embodiment, a microarray composition includes a three-dimensional solid support and a plurality of reactive microbeads positioned on the solid support in spatially distinct and addressable locations.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: April 11, 2017
    Inventor: Vladislav B. Bergo
  • Publication number: 20170089891
    Abstract: Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
    Type: Application
    Filed: October 3, 2016
    Publication date: March 30, 2017
    Inventors: Mark J Lim, Vladislav B. Bergo, Kenneth J. Rothschild
  • Patent number: 9513285
    Abstract: Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: December 6, 2016
    Assignee: AmberGen, Inc.
    Inventors: Mark J. Lim, Vladislav B. Bergo, Kenneth J. Rothschild
  • Publication number: 20160008785
    Abstract: Devices and methods for producing and analyzing microarrays are disclosed. In an embodiment, a method for converting a library of beads to an array of analytes includes positioning a plurality of beads having one or more analytes bound therein on a solid support in a spatially separated manner, causing the analytes to be released from the plurality of microparticles, and localizing the released analytes in discrete spots.
    Type: Application
    Filed: July 9, 2015
    Publication date: January 14, 2016
    Inventor: Vladislav B. Bergo
  • Publication number: 20140323330
    Abstract: Microarray compositions suitable for analysis by one or several spectrographic methods are disclosed. In an embodiment, a microarray composition includes a three-dimensional solid support and a plurality of reactive microbeads positioned on the solid support in spatially distinct and addressable locations.
    Type: Application
    Filed: April 24, 2014
    Publication date: October 30, 2014
    Inventor: Vladislav B. Bergo
  • Publication number: 20140235471
    Abstract: Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
    Type: Application
    Filed: December 17, 2013
    Publication date: August 21, 2014
    Applicant: Ambergen, Inc.
    Inventors: Vladislav B. Bergo, Mark J. Lim, Kenneth J. Rothschild
  • Patent number: 8507648
    Abstract: This invention relates to the detection and analysis by mass spec of nascent proteins, and in particular truncated proteins, translated within cellular or cell-free translation systems. N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as mass difference.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: August 13, 2013
    Assignee: Ambergen, Inc.
    Inventors: Alex Garvin, Sadanand Gite, Vladislav B. Bergo, Kenneth J. Rothschild
  • Publication number: 20120202709
    Abstract: Devices and methods for producing and analyzing microarrays are disclosed. In an embodiment, a method for converting a library of beads to an array of analytes includes positioning a plurality of beads having one or more analytes bound therein on a solid support in a spatially separated manner, causing the analytes to be released from the plurality of microparticles, and localizing the released analytes in discrete spots.
    Type: Application
    Filed: February 9, 2012
    Publication date: August 9, 2012
    Applicant: Adeptrix Corp.
    Inventor: Vladislav B. Bergo
  • Publication number: 20120077688
    Abstract: Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
    Type: Application
    Filed: June 29, 2011
    Publication date: March 29, 2012
    Inventors: Vladislav B. Bergo, Mark J. Lim, Kenneth J. Rothschild
  • Publication number: 20110015369
    Abstract: This invention relates to the detection and analysis by mass spec of nascent proteins, and in particular truncated proteins, translated within cellular or cell-free translation systems. N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as mass difference.
    Type: Application
    Filed: August 4, 2010
    Publication date: January 20, 2011
    Inventors: ALEX M. GARVIN, SADANAND GITE, VLADISLAV B. BERGO, KENNETH J. ROTHSCHILD
  • Patent number: 7807407
    Abstract: This invention relates to the detection and analysis by mass spec of nascent proteins, and in particular truncated proteins, translated within cellular or cell-free translation systems. N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as a mass difference.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: October 5, 2010
    Assignee: AmberGen, Inc.
    Inventors: Alex M. Garvin, Sadanand Gite, Vladislav B. Bergo, Kenneth J. Rothschild