Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.

Abstract: A method for monitoring operation of a machine includes receiving machine operation data including a first data channel indicative of a sensed condition at a first location on the machine, wherein the machine operation data is collected during one or more work cycles of the machine, and extracting at least a portion of the machine operation data, including data associated with the first data channel.

Abstract: A method for monitoring operation of a machine includes receiving machine operation data including a first data channel indicative of a sensed condition at a first location on the machine, wherein the machine operation data is collected during one or more work cycles of the machine, and extracting at least a portion of the machine operation data, including data associated with the first data channel.

Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

Abstract: A thin sensor film that is capable of indicating temperature and an associated sensor readout kit that illuminates the sensor film and detects the return fluorescence for analysis to determine temperature. The sensor film may be detached and reattached in order to be reused. The initial design achieves high sensitivity and accuracy in the range of interest to biologistics and can potentially address temperatures ranging from ?200 to 300° C. A variation allows for the use of optical fibers for measurements of surfaces inside enclosures.

Abstract: A thin sensor film that is capable of indicating temperature and an associated sensor readout kit that illuminates the sensor film and detects the return fluorescence for analysis to determine temperature. The sensor film may be detached and reattached in order to be reused. The initial design achieves high sensitivity and accuracy in the range of interest to biologistics and can potentially address temperatures ranging from ?200 to 300° C. A variation allows for the use of optical fibers for measurements of surfaces inside enclosures.

Abstract: A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

Abstract: A system for measuring the blood loss comprises a measuring device that determines the hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, the hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

Abstract: A system and method for determining a presence of a mobile device located in a predetermined detection zone within a vehicle may include a plurality of transmitters located within the vehicle, in which each of the plurality of transmitters is configured to transmit an acoustic signal into an acoustic environment within the vehicle, and in which each of the acoustic signals comprises at least one ultrasonic pulse, a mobile device configured to periodically record sounds in the acoustic environment, and a processor configured to determine that a periodically recorded sound by the mobile device comprises each of the acoustic signals transmitted by the plurality of transmitters, determine a location of the mobile device within the vehicle based on the acoustic signals recorded by the mobile device, and determine that the location of the mobile device matches the predetermined detection zone.

Abstract: A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector, The container receives blood and other fluids from a patient during a medical procedure, Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

Abstract: A system and method for determining a presence of a mobile device located in a predetermined detection zone within a vehicle may include a plurality of transmitters located within the vehicle, in which each of the plurality of transmitters is configured to transmit an acoustic signal into an acoustic environment within the vehicle, and in which each of the acoustic signals comprises at least one ultrasonic pulse, a mobile device configured to periodically record sounds in the acoustic environment, and a processor configured to determine that a periodically recorded sound by the mobile device comprises each of the acoustic signals transmitted by the plurality of transmitters, determine a location of the mobile device within the vehicle based on the acoustic signals recorded by the mobile device, and determine that the location of the mobile device matches the predetermined detection zone.

Abstract: A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

Abstract: A system includes a thermographic temperature sensor that may measure a temperature of a fluid. The thermographic temperature sensor includes a probe, an optical source coupled to the probe, and a detector coupled to the probe. The system also includes a housing of the probe; and a light pipe of the probe disposed within the housing and including a thermographic phosphor that may phosphoresce in response to absorbing light from the optical source. The phosphorescence by the thermographic phosphor is representative of a temperature of the fluid within a flow path of the fluid, and the detector may detect the phosphorescence by the thermographic phosphor.

Abstract: A thermographic temperature sensor includes a probe having a housing and a light pipe disposed within the housing. The light pipe includes a thermographic phosphor that may phosphoresce in response to absorbing light. The phosphorescence by the thermographic phosphor is representative of a temperature of a fluid in contact with the probe, and a surface area of the light pipe is not in contact with an inner surface of the housing.

Abstract: A system and method for determining a presence of a mobile device located in a predetermined detection zone within a vehicle may include a plurality of transmitters located within the vehicle, in which each of the plurality of transmitters is configured to transmit an acoustic signal into an acoustic environment within the vehicle, and in which each of the acoustic signals comprises at least one ultrasonic pulse, a mobile device configured to periodically record sounds in the acoustic environment, and a processor configured to determine that a periodically recorded sound by the mobile device comprises each of the acoustic signals transmitted by the plurality of transmitters, determine a location of the mobile device within the vehicle based on the acoustic signals recorded by the mobile device, and determine that the location of the mobile device matches the predetermined detection zone.

Abstract: A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

Abstract: An interactive television program guide system with program series reminder and recording capabilities is provided. The system allows a user to set a reminder or schedule a recording for a single episode or for each episode of a program series. In addition, other options may be provided that allow the user to determine, for example, whether to schedule reminders/recordings for episodes on all channels on which the program airs or only on a selected channels, whether to schedule reminders/recordings for all episodes including reruns or only new episodes, whether to schedule reminders/recordings for network or syndicated episodes, and whether to schedule reminders/recordings for episodes on all days or only on selected days of the week. Before the scheduled broadcast time of each episode of each selected program series, the system sends a reminder message to the user that reminds the user of the program episode or sends a record command to a videocassette recorder to initiate recording of the episode.

Abstract: A thin sensor film that is capable of indicating temperature and an associated sensor readout kit that illuminates the sensor film and detects the return fluorescence for analysis to determine temperature. The sensor film may be detached and reattached in order to be reused. The initial design achieves high sensitivity and accuracy in the range of interest to biologistics and can potentially address temperatures ranging from ?200 to 300° C. A variation allows for the use of optical fibers for measurements of surfaces inside enclosures.

Abstract: An interactive television program guide is provided in which advertisements may be displayed on program guide screens. Banner advertisements may be displayed above and below program listings. Panel advertisements may be provided adjacent to program listings. The advertisements may contain video. The advertisements may be used to promote television programs and conventional goods and services. When a user selects an advertisement, the program guide provides the user with an opportunity to order products or services, request information, set reminders for upcoming programs, view program descriptions, record programs, or take other such actions. Embedded advertisements may be provided within the program listings region and may be automatically displayed immediately adjacent to related program listings.