Patents by Inventor W. David Lee

W. David Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11266313
    Abstract: A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: March 8, 2022
    Assignees: Massachusetts Institute of Technology, Duke University
    Inventors: Moungi G. Bawendi, Jorge M. Ferrer, W. David Lee, Lisa F. Marshall, David G. Kirsch
  • Publication number: 20210228083
    Abstract: Disclosed techniques include skin diagnostics using optical signatures. A plurality of optical excitation light wavelength bands is scanned on a material sample, wherein the material sample exhibits optical spectral characteristics along the light wavelength spectrum. Excitation response wavelengths emitted by the material sample are captured in response to the plurality of optical excitation light wavelength bands, wherein the capturing is accomplished using an imaging sensor. Output values of a plurality of pixels of an image from the imaging sensor are measured, wherein the image represents excitation response wavelengths captured by the imaging sensor, wherein the measuring detects optical spectral characteristics of the material sample, and wherein the optical spectral characteristics are in response to the plurality of optical excitation light wavelength bands.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 29, 2021
    Applicant: Precision Healing, Inc.
    Inventors: David B. Strasfeld, Ira M. Herman, W. David Lee, Ryan Daniel Williams, Sean P. Madden
  • Publication number: 20210231566
    Abstract: Disclosed techniques include exudate analysis using optical signatures. Access to a tissue exudate sample is obtained, wherein the tissue exudate sample contains one or more analytes representing a state of the tissue. The one or more analytes are isolated from the exudate sample on a substrate. The exudate is transferred from the substrate to an immunoassay. The immunoassay is illuminated with photons, wherein the illuminating comprises a controlled photon exposure. The controlled photon exposure comprises ambient lighting and/or one or more fluorescence excitation light wavelength bands. Light emanating from the immunoassay is imaged, wherein the imaging captures intensities of light wavelengths across the light wavelength spectrum. The imaging captures reflected light and fluorescent emanating light. A signature for the one or more analytes is generated, based on analysis of the intensities that were imaged. The signature expresses a magnitude for each of the one or more analytes.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 29, 2021
    Applicant: Precision Healing, Inc.
    Inventors: Ryan Daniel Williams, Ira M. Herman, W David Lee, David B. Strasfeld, Sean P. Madden
  • Publication number: 20210048491
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: March 25, 2020
    Publication date: February 18, 2021
    Inventor: W. David Lee
  • Patent number: 10813554
    Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: October 27, 2020
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
  • Patent number: 10791937
    Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: October 6, 2020
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
  • Publication number: 20200225160
    Abstract: The present invention provides compositions and methods for imaging tumor resections.
    Type: Application
    Filed: March 25, 2020
    Publication date: July 16, 2020
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Moungi G. Bawendi, Jorge Ferrer
  • Publication number: 20200205930
    Abstract: Embodiments related to methods of use of an image analysis system for identifying residual cancer cells after surgery are disclosed. In some embodiments, a patient-specific threshold used to detect abnormal cells in a surgical site can be determined. A medical imaging device can be configured to produce a set of images of an anatomy of a patient. An image analysis system, comprising one or more processors, can be configured to receive the set of images, and analyze the set of images to determine a patient-specific threshold to use to detect abnormal tissue of the patient.
    Type: Application
    Filed: December 10, 2019
    Publication date: July 2, 2020
    Applicant: Lumicell, Inc.
    Inventors: David B. Strasfeld, Jorge Ferrer, W. David Lee
  • Publication number: 20190239750
    Abstract: A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.
    Type: Application
    Filed: April 15, 2019
    Publication date: August 8, 2019
    Inventors: Moungi G. Bawendi, Jorge M. Ferrer, W. David Lee, Lisa F. Marshall, David G. Kirsch
  • Publication number: 20190223954
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery
    Type: Application
    Filed: March 28, 2019
    Publication date: July 25, 2019
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Patent number: 10285759
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 14, 2019
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Patent number: 10039603
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: August 7, 2018
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Publication number: 20180021090
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery
    Type: Application
    Filed: September 29, 2017
    Publication date: January 25, 2018
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Publication number: 20170299668
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: July 5, 2017
    Publication date: October 19, 2017
    Inventor: W. David LEE
  • Patent number: 9763577
    Abstract: The present invention provides compositions and methods for imaging, for example, tumor resections.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 19, 2017
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Moungi G. Bawendi, Jorge Ferrer
  • Patent number: 9532835
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: January 3, 2017
    Assignee: Lumicell, Inc.
    Inventor: W. David Lee
  • Publication number: 20160317037
    Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
  • Publication number: 20160310213
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery
    Type: Application
    Filed: July 6, 2016
    Publication date: October 27, 2016
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Patent number: 9314304
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: April 19, 2016
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Publication number: 20160025632
    Abstract: The present invention provides compositions and methods for imaging tumor resections.
    Type: Application
    Filed: September 8, 2015
    Publication date: January 28, 2016
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Moungi G. Bawendi, Jorge Ferrer