Patents by Inventor W. David Lee
W. David Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140301950Abstract: The present invention provides compositions and methods for imaging, for example, tumor resections.Type: ApplicationFiled: March 14, 2014Publication date: October 9, 2014Applicant: LUMICELL, INC.Inventors: W. DAVID LEE, MOUNGI G. BAWENDI, JORGE FERRER
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Publication number: 20140276103Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Lumicell, Inc.Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
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Publication number: 20140276102Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Lumicell, Inc.Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
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Patent number: 8836334Abstract: This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response.Type: GrantFiled: January 4, 2013Date of Patent: September 16, 2014Assignee: T2 Biosystems, Inc.Inventors: W. David Lee, David A. Berry
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Publication number: 20140207129Abstract: The invention provides systems and method for the removal of diseased cells during surgeryType: ApplicationFiled: March 19, 2014Publication date: July 24, 2014Applicant: Lumicell, Inc.Inventor: W. David Lee
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Patent number: 8704517Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: October 28, 2011Date of Patent: April 22, 2014Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Patent number: 8624592Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: July 27, 2010Date of Patent: January 7, 2014Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Publication number: 20130229179Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: ApplicationFiled: March 28, 2013Publication date: September 5, 2013Applicant: T2 Biosystems, Inc.Inventor: W. David LEE
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Patent number: 8368402Abstract: This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response.Type: GrantFiled: November 8, 2007Date of Patent: February 5, 2013Assignee: T2 Biosystems, Inc.Inventors: W. David Lee, David A. Berry
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Patent number: 8344731Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: July 27, 2010Date of Patent: January 1, 2013Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Patent number: 8334693Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: July 27, 2010Date of Patent: December 18, 2012Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Publication number: 20120313639Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: ApplicationFiled: June 25, 2012Publication date: December 13, 2012Applicant: T2 Biosystems, Inc.Inventor: W. David LEE
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Patent number: 8310231Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: July 27, 2010Date of Patent: November 13, 2012Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Patent number: 8310232Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: July 27, 2010Date of Patent: November 13, 2012Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Publication number: 20120107839Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: ApplicationFiled: October 28, 2011Publication date: May 3, 2012Applicant: T2 Biosystems, Inc.Inventor: W. David Lee
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Patent number: 8102176Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: GrantFiled: September 2, 2008Date of Patent: January 24, 2012Assignee: T2 Biosystems, Inc.Inventor: W. David Lee
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Publication number: 20110018538Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: ApplicationFiled: July 27, 2010Publication date: January 27, 2011Applicant: T2 Biosystems, Inc.Inventor: W. David Lee
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Publication number: 20110020953Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: ApplicationFiled: July 27, 2010Publication date: January 27, 2011Applicant: T2 Biosystems, Inc.Inventor: W. David Lee
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Publication number: 20110021908Abstract: The present invention provides compositions and methods for imaging tumor resections.Type: ApplicationFiled: May 27, 2010Publication date: January 27, 2011Applicant: LUMICELL DIAGNOSTICS, INC.Inventors: W. David Lee, Moungi G. Bawendi, Jorge Ferrer
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Publication number: 20110020787Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.Type: ApplicationFiled: July 27, 2010Publication date: January 27, 2011Applicant: T2 Biosystems, Inc.Inventor: W. David Lee