Patents by Inventor W. David Lee

W. David Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140301950
    Abstract: The present invention provides compositions and methods for imaging, for example, tumor resections.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 9, 2014
    Applicant: LUMICELL, INC.
    Inventors: W. DAVID LEE, MOUNGI G. BAWENDI, JORGE FERRER
  • Publication number: 20140276103
    Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
  • Publication number: 20140276102
    Abstract: Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer, David B. Strasfeld
  • Patent number: 8836334
    Abstract: This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: September 16, 2014
    Assignee: T2 Biosystems, Inc.
    Inventors: W. David Lee, David A. Berry
  • Publication number: 20140207129
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery
    Type: Application
    Filed: March 19, 2014
    Publication date: July 24, 2014
    Applicant: Lumicell, Inc.
    Inventor: W. David Lee
  • Patent number: 8704517
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: April 22, 2014
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Patent number: 8624592
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: January 7, 2014
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Publication number: 20130229179
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: March 28, 2013
    Publication date: September 5, 2013
    Applicant: T2 Biosystems, Inc.
    Inventor: W. David LEE
  • Patent number: 8368402
    Abstract: This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: February 5, 2013
    Assignee: T2 Biosystems, Inc.
    Inventors: W. David Lee, David A. Berry
  • Patent number: 8344731
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: January 1, 2013
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Patent number: 8334693
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: December 18, 2012
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Publication number: 20120313639
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: June 25, 2012
    Publication date: December 13, 2012
    Applicant: T2 Biosystems, Inc.
    Inventor: W. David LEE
  • Patent number: 8310231
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: November 13, 2012
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Patent number: 8310232
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: November 13, 2012
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Publication number: 20120107839
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: October 28, 2011
    Publication date: May 3, 2012
    Applicant: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Patent number: 8102176
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: January 24, 2012
    Assignee: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Publication number: 20110018538
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Applicant: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Publication number: 20110020953
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Applicant: T2 Biosystems, Inc.
    Inventor: W. David Lee
  • Publication number: 20110021908
    Abstract: The present invention provides compositions and methods for imaging tumor resections.
    Type: Application
    Filed: May 27, 2010
    Publication date: January 27, 2011
    Applicant: LUMICELL DIAGNOSTICS, INC.
    Inventors: W. David Lee, Moungi G. Bawendi, Jorge Ferrer
  • Publication number: 20110020787
    Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Applicant: T2 Biosystems, Inc.
    Inventor: W. David Lee