Patents by Inventor Waldemar Priebe

Waldemar Priebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of preliposomal Annamycin lyophilizate
    Patent number: 12257261
    Abstract: Provided is a method of making a preliposomal Annamycin lyophilizate, the composition made by the method, and the use of the composition made thereby in the treatment of cancer.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: March 25, 2025
    Assignees: Board of Regents, The University of Texas System, Moleculin Biotech, Inc.
    Inventors: Donald Picker, Waldemar Priebe
  • Method of reconstituting liposomal annamycin
    Patent number: 12257262
    Abstract: Methods of reconstituting lyophilized Annamycin and methods of treating patients are described.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: March 25, 2025
    Assignees: Board of Regents, The University of Texas System, Moleculin Biotech, Inc.
    Inventors: Donald Picker, Waldemar Priebe
  • Method of reconstituting liposomal annamycin
    Patent number: 11980634
    Abstract: Methods of reconstituting lyophilized Annamycin and methods of treating patients are described.
    Type: Grant
    Filed: October 5, 2023
    Date of Patent: May 14, 2024
    Assignees: Moleculin Biotech, Inc., Board of Regents, The University of Texas System
    Inventors: Donald Picker, Waldemar Priebe
  • Preparation of preliposomal annamycin lyophilizate
    Patent number: 11951118
    Abstract: Provided is a method of making a preliposomal Annamycin lyophilizate, the composition made by the method, and the use of the composition made thereby in the treatment of cancer.
    Type: Grant
    Filed: October 5, 2023
    Date of Patent: April 9, 2024
    Assignees: Moleculin Biotech, Inc., Board of Regents, The University of Texas System
    Inventors: Donald Picker, Waldemar Priebe
  • Esters of 2-deoxy-monosaccharides with anti proliferative activity
    Patent number: 11925654
    Abstract: Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.
    Type: Grant
    Filed: June 4, 2021
    Date of Patent: March 12, 2024
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Marcin Cybulski, Izabela Fokt, Stanislaw Skora, Charles Conrad, Timothy Madden
  • PREPARATION OF PRELIPOSOMAL ANNAMYCIN LYOPHILIZATE
    Publication number: 20240041909
    Abstract: Provided is a method of making a preliposomal Annamycin lyophilizate, the composition made by the method, and the use of the composition made thereby in the treatment of cancer.
    Type: Application
    Filed: October 5, 2023
    Publication date: February 8, 2024
    Inventors: Donald Picker, Waldemar Priebe
  • METHOD OF RECONSTITUTING LIPOSOMAL ANNAMYCIN
    Publication number: 20240024345
    Abstract: Methods of reconstituting lyophilized Annamycin and methods of treating patients are described.
    Type: Application
    Filed: October 5, 2023
    Publication date: January 25, 2024
    Inventors: Donald Picker, Waldemar Priebe
  • ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY
    Publication number: 20220023326
    Abstract: Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.
    Type: Application
    Filed: June 4, 2021
    Publication date: January 27, 2022
    Inventors: Waldemar Priebe, Marcin Cybulski, Izabela Fokt, Stanislaw Skora, Charles Conrad, Timothy Madden
  • Esters of 2-deoxy-monosaccharides with anti proliferative activity
    Patent number: 11026960
    Abstract: Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 8, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Marcin Cybulski, Izabela Fokt, Stanislaw Skora, Charles Conrad, Timothy Madden
  • Caffeic acid derivatives and uses thereof
    Patent number: 10703721
    Abstract: In one aspect, the present disclosure provides caffeic acid derivatives of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure provides pharmaceutical compositions and methods of using of the compounds disclosed herein, including for the treatment of cancer.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: July 7, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Stanislaw Skora, Izabela Fokt, Rafal Zielinski, Arumugam Jayakumar, Radjendirane Venugopal
  • DNA binding agents with a minor groove binding tail
    Patent number: 10358439
    Abstract: Provided herein are compounds which intercalate into the DNA of a cell and are capable of crossing the blood brain barrier of a formula provided herein. Pharmaceutical compositions of the compounds and methods of treating cancer, for example brain, lung, or pancreatic cancer, are also provided herein.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: July 23, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Liwei Guo, Arkadiusz Kazimierski, Izabela Fokt, Charles Conrad, Timothy Madden
  • Esters of 2-deoxy-monosacharides with anti proliferative activity
    Patent number: 10201554
    Abstract: Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: February 12, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Marcin Cybulski, Izabela Fokt, Stanislaw Skora, Charles Conrad, Timothy Madden
  • ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY
    Publication number: 20160184336
    Abstract: Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.
    Type: Application
    Filed: April 4, 2014
    Publication date: June 30, 2016
    Applicant: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Marcin Cybulski, Izabela Fokt, Stanislaw Skora, Charles Conrad, Timothy Madden
  • Compounds for treatment of cell proliferative diseases
    Patent number: 9096499
    Abstract: The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as kinase inhibitors, cause the downregulation of c-myc, and inhibit the growth and survival of cancerous cell lines.
    Type: Grant
    Filed: January 3, 2014
    Date of Patent: August 4, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Nicholas Donato, Moshe Talpaz, Slawomir Szymanski, Izabela Fokt, Alexander Levitzki
  • Inhibitors of proliferation and activation of signal transducer and activator of transcription (STATs)
    Patent number: 9000179
    Abstract: Pyridine compounds effective in modulation STAT3 and/or STAT5 activation are provided that are useful in the prevention and treatment of proliferative disease and conditions including cancer, inflammation and proliferative skin disorders.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: April 7, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Stanislaw Skora, Timothy Madden, Izabela Fokt, Charles Conrad
  • Acetates of 2-deoxy monosaccharides with anticancer activity
    Patent number: 8927506
    Abstract: Novel compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are provided herein.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: January 6, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Marcin Cybulski, Izabela Fokt, Stanislaw Skora, Charles Conrad, Timothy Madden
  • Orally bioavailable caffeic acid related anticancer drugs
    Patent number: 8779151
    Abstract: The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as inhibitors of Jak2/STAT3 pathways and downstream targets and inhibit the growth and survival of cancerous cell lines.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: July 15, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Waldemar Priebe, Izabela Fokt, Slawomir Szymanski, Timothy Madden, Jeffrey Myers, Charles Conrad
  • Compounds for treatment of cell proliferative diseases
    Patent number: 8648102
    Abstract: The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as kinase inhibitors, cause the downregulation of c-myc, and inhibit the growth and survival of cancerous cell lines.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: February 11, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Nicholas Donato, Moshe Talpaz, Slawomir Szymanski, Izabela Fokt, Alexander Levitzki
  • Inhibitors of proliferation and activation of signal transducer and activators of transcription (STATS)
    Patent number: 8637675
    Abstract: Pyridine compounds effective in modulation STAT3 and/or STAT5 activation are provided that are useful in the prevention and treatment of proliferative disease and conditions including cancer, inflammation and proliferative skin disorders.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: January 28, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Stanislaw Skora, Timothy Madden, Izabela Fokt, Charles Conrad
  • METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS
    Publication number: 20130244986
    Abstract: Embodiments of the invention generally relate to pharmaceutical compositions containing at least one caffeic acid compound and methods for the topical treatment of proliferative and inflammatory skin disorders such as plaque psoriasis, atopic dermatitis, and other disorders. In some embodiments, the topical treatment includes applications of the pharmaceutical composition containing at least one caffeic acid compound or a mixture of caffeic acid compounds such as caffeic acid ester compounds, caffeic acid amide compounds, analogues thereof, derivatives thereof, salts thereof, or mixtures thereof. The pharmaceutical composition or topical dosage may contain the caffeic acid compound at a concentration by weight within a range from about 0.01% to about 20%, preferably, from about 0.1% to about 15%, preferably, from about 1% to about 10%, more preferably, from about 3% to about 7%, and more preferably, from about 4% to about 6%.
    Type: Application
    Filed: April 26, 2013
    Publication date: September 19, 2013
    Applicant: Moleculin LLC
    Inventors: Waldemar Priebe, Charles Conrad, Timothy Madden