Abstract: Circuits/methods for controlling the startup of multiple parallel power converters that avoid inrush current or switch overstress in an added power converter or a power converter having fault conditions. Embodiments include node status detectors coupled to nodes within parallel-connected power converters to monitor voltage/current and configured in some embodiments to work in parallel with an output status detector measuring the startup output voltage of a power converter. With charge pump-based power converters, the node status detectors ensure that the power converter pump capacitors are charged while the output capacitor is charged as well. For such embodiments, a soft-start period of startup may be considered finished if both the shared output capacitors and the power converter pump capacitors are charged to target values. Embodiments may also be used for fault detection during steady-state operation.

Abstract: h A method for using a trained machine learning model to predict risk of incident opioid use disorder (OUD) and/or of N an opioid overdose episode for a subject. The method comprises using at least one computer hardware processor to perform: accessing data associated with the subject, wherein the data comprises values for a plurality of predictors; generating input features for the trained machine learning model from the data; and providing the input features as input to the trained machine learning model to obtain an output indicative of the risk of OUD and/or of the opioid overdose episode for the subject, wherein the trained machine learning model comprises a first plurality of values for a respective first plurality of parameters, the first plurality of values used by the at least one computer hardware processor to obtain the output from the input features.

Abstract: Circuits/methods for controlling the startup of multiple parallel power converters that avoid inrush current or switch overstress in an added power converter or a power converter having fault conditions. Embodiments include node status detectors coupled to nodes within parallel-connected power converters to monitor voltage/current and configured in some embodiments to work in parallel with an output status detector measuring the startup output voltage of a power converter. With charge pump-based power converters, the node status detectors ensure that the power converter pump capacitors are charged while the output capacitor is charged as well. For such embodiments, a softstart period of startup may be considered finished if both the shared output capacitors and the power converter pump capacitors are charged to target values. Embodiments may also be used for fault detection during steady-state operation.

Abstract: Circuit embodiments for a switched-capacitor power converter, and/or methods of operation of such a converter, that robustly deal with various startup scenarios, are efficient and low cost, and have quick startup times to steady-state converter operation. Embodiments prevent full charge pump capacitor discharge during shutdown of a converter and/or rebalance charge pump capacitors during a startup period before switching operation by discharging and/or precharging the charge pump capacitors. Embodiments may include a dedicated rebalancer circuit that includes a voltage sensing circuit coupled to an output voltage of a converter, and a balance circuit configured to charge or discharge each charge pump capacitor towards a target steady-state multiple of the output voltage of the converter as a function of an output signal from the voltage sensing circuit indicative of the output voltage. Embodiments prevent or limit current in-rush to a converter during a startup state.

Abstract: Circuits/methods for controlling the startup of multiple parallel power converters that avoid inrush current or switch overstress in an added power converter or a power converter having fault conditions. Embodiments include node status detectors coupled to nodes within parallel-connected power converters to monitor voltage/current and configured in some embodiments to work in parallel with an output status detector measuring the startup output voltage of a power converter. With charge pump-based power converters, the node status detectors ensure that the power converter pump capacitors are charged while the output capacitor is charged as well. For such embodiments, a softstart period of startup may be considered finished if both the shared output capacitors and the power converter pump capacitors are charged to target values. Embodiments may also be used for fault detection during steady-state operation.

Abstract: Circuit embodiments for a switched-capacitor power converter, and/or methods of operation of such a converter, that robustly deal with various startup scenarios, are efficient and low cost, and have quick startup times to steady-state converter operation. Embodiments prevent full charge pump capacitor discharge during shutdown of a converter and/or rebalance charge pump capacitors during a startup period before switching operation by discharging and/or precharging the charge pump capacitors. Embodiments may include a dedicated rebalancer circuit that includes a voltage sensing circuit coupled to an output voltage of a converter, and a balance circuit configured to charge or discharge each charge pump capacitor towards a target steady-state multiple of the output voltage of the converter as a function of an output signal from the voltage sensing circuit indicative of the output voltage. Embodiments prevent or limit current in-rush to a converter during a startup state.

Abstract: A single integrated circuit DC-to-DC conversion solution that can be used in conjunction with product designs requiring at least two different DC-to-DC conversion ratios, and in particular both divide-by-2 and divide-by-3 DC-to-DC buck conversion ratios or both multiply-by-2 and multiply-by-3 DC-to-DC boost conversion ratios. Embodiments are reconfigurable between a first Dickson converter configuration that includes at least two non-parallel capacitors (any of which may be off-chip) and associated controlled multi-phase switching to achieve a first conversion ratio, and a second Dickson converter configuration that includes a lesser equivalent number of capacitors than the first circuit configuration (which may be accomplished by parallelizing at least two non-parallel capacitors of the first configuration) and associated controlled multi-phase switching to achieve a second conversion ratio different from the first conversion ratio.

Abstract: Over-current detection circuits and methods for adiabatic power converters that provide numerous advantages over known solutions, including simple digital control, enabling trimming to be done in the low voltage domain, and avoidance of high-voltage sense current mirrors. Embodiments include a slope detector circuit configured to measure a slope of the immediate output voltage VX of an adiabatic power converter during a charge pump clock cycle, compare the measured slope to a pre-determined value representing a slope of an over-current condition, and assert a flag if comparison indicates an over-current condition. An auto-calibration circuit may be included which presents a set of known loads across the output of an adiabatic power converter at device startup, measures the resulting counts from the slope detector counter, and extrapolates to a count that corresponds to a maximum allowed current.

Abstract: Circuit embodiments for a switched-capacitor power converter, and/or methods of operation of such a converter, that robustly deal with various startup scenarios, are efficient and low cost, and have quick startup times to steady-state converter operation. Embodiments prevent full charge pump capacitor discharge during shutdown of a converter and/or rebalance charge pump capacitors during a startup period before switching operation by discharging and/or precharging the charge pump capacitors. Embodiments may include a dedicated rebalancer circuit that includes a voltage sensing circuit coupled to an output voltage of a converter, and a balance circuit configured to charge or discharge each charge pump capacitor towards a target steady-state multiple of the output voltage of the converter as a function of an output signal from the voltage sensing circuit indicative of the output voltage. Embodiments prevent or limit current in-rush to a converter during a startup state.

Abstract: Circuit embodiments for a switched-capacitor power converter, and/or methods of operation of such a converter, that robustly deal with various startup scenarios, are efficient and low cost, and have quick startup times to steady-state converter operation. Embodiments prevent full charge pump capacitor discharge during shutdown of a converter and/or rebalance charge pump capacitors during a startup period before switching operation by discharging and/or precharging the charge pump capacitors. Embodiments may include a dedicated rebalancer circuit that includes a voltage sensing circuit coupled to an output voltage of a converter, and a balance circuit configured to charge or discharge each charge pump capacitor towards a target steady-state multiple of the output voltage of the converter as a function of an output signal from the voltage sensing circuit indicative of the output voltage. Embodiments prevent or limit current in-rush to a converter during a startup state.

Abstract: A single integrated circuit DC-to-DC conversion solution that can be used in conjunction with product designs requiring at least two different DC-to-DC conversion ratios, and in particular both divide-by-2 and divide-by-3 DC-to-DC buck conversion ratios or both multiply-by-2 and multiply-by-3 DC-to-DC boost conversion ratios. Embodiments are reconfigurable between a first Dickson converter configuration that includes at least two non-parallel capacitors (any of which may be off-chip) and associated controlled multi-phase switching to achieve a first conversion ratio, and a second Dickson converter configuration that includes a lesser equivalent number of capacitors than the first circuit configuration (which may be accomplished by parallelizing at least two non-parallel capacitors of the first configuration) and associated controlled multi-phase switching to achieve a second conversion ratio different from the first conversion ratio.

Abstract: A single integrated circuit DC-to-DC conversion solution that can be used in conjunction with product designs requiring at least two different DC-to-DC conversion ratios, and in particular both divide-by-2 and divide-by-3 DC-to-DC buck conversion ratios or both multiply-by-2 and multiply-by-3 DC-to-DC boost conversion ratios. Embodiments are reconfigurable between a first Dickson converter configuration that includes at least two non-parallel capacitors (any of which may be off-chip) and associated controlled multi-phase switching to achieve a first conversion ratio, and a second Dickson converter configuration that includes a lesser equivalent number of capacitors than the first circuit configuration (which may be accomplished by parallelizing at least two non-parallel capacitors of the first configuration) and associated controlled multi-phase switching to achieve a second conversion ratio different from the first conversion ratio.

Abstract: Methods and compositions are provided here to manage tractional membranes, as well as other diseases and disorders of the eye. Compositions comprising microbubbles associated with enzymes or vitreolytic agents, are provided. The method of the present invention involves administration of the microbubble and an enzyme or vitreolytic agent to a subject in need thereof, followed by application of ultrasound.

Abstract: Disclosed herein are methods for treating eye injuries by administering one or more angiotensin peptides to a subject with an eye injury.

Abstract: Disclosed herein are methods for treating eye injuries by administering one or more angiotensin peptides to a subject with an eye injury.

Abstract: One embodiment of a mobile airline check-in counter with integrated baggage scale wherein the mobile unit contains a plurality of shelves to house supplies and equipment associated with the airline baggage check-in process and including an integrated and retractable baggage scale mounted on a caster system. Other embodiments are described.

Abstract: The present invention provides methods and compositions for improving biomass, as well as, the drought resistance of plants. More specifically, the present invention utilizes expression of aspartate carboxylase in plants and plant cells.