Abstract: A web of preformed bags includes an exterior sheet material and an expandable slit sheet material. The exterior sheet material and an expandable slit sheet material are coupled along longitudinal seams. The expandable slit sheet material has slits arranged substantially parallel to the longitudinal seams. The web has a longitudinal fold such that the expandable slit sheet material is on the inner side of the exterior sheet material. The longitudinal fold is substantially parallel to the longitudinal seams. When the expandable slit sheet material is in an unexpanded form, the exterior sheet material extends farther away from the longitudinal seams than the expandable slit sheet material extends from the longitudinal seams. The expandable slit sheet material in each of the bags is expandable from the unexpanded form to an expanded form.

Abstract: A web of preformed bags includes a sheet material and a cushioning material. The sheet material includes two sheets that are arranged to form a series of bags. The sheets are connected together to form sides of each of the bags. Each of the bags is bounded by an opening and the sides where sheets are connected together. The cushioning material is coupled to inner surfaces of the sheets in each of the bags. The web further includes a line of weakness in at least one of the sheets between each of the bags. After an object is loaded in one of the bags, the opening of the one of the bags is configured to be sealed closed with the object therein such that the cushioning material in the one of the bags is arranged to cushion the object when the one of the bags is sealed closed.

Abstract: A nanoglue is formed with one or more bioadhesive polymers, one or more dendrimers, and optionally one or more therapeutic, prophylactic, or diagnostic agents. The bioadhesive polymers and dendrimers are modified with functional groups to permit crosslinking upon one or more stimuli, e.g., ultraviolet irradiation, and form hydrogel in situ at tissue sites. In the repair of corneal wounds, the nanoglue leads to improved rate of healing with less scarring and less inflammation, compared to non-treated cornea or ones treated with sutures. Therapeutic agents can be covalently conjugated to the precursor components and be delivered to specific eye compartments, providing a more efficacious treatment formulation of ocular disorders than delivering drugs in their free forms. Methods of making and using the hydrogel and hydrogel precursor compositions are also provided.

Abstract: A nanoglue is formed with one or more bioadhesive polymers, one or more dendrimers, and optionally one or more therapeutic, prophylactic, or diagnostic agents. The bioadhesive polymers and dendrimers are modified with functional groups to permit crosslinking upon one or more stimuli, e.g., ultraviolet irradiation, and form hydrogel in situ at tissue sites. In the repair of corneal wounds, the nanoglue leads to improved rate of healing with less scarring and less inflammation, compared to non-treated cornea or ones treated with sutures. Therapeutic agents can be covalently conjugated to the precursor components and be delivered to specific eye compartments, providing a more efficacious treatment formulation of ocular disorders than delivering drugs in their free forms. Methods of making and using the hydrogel and hydrogel precursor compositions are also provided.

Abstract: Methods for increasing the encapsulation or incorporation of Sunitinib into polymeric matrices have been developed. The resulting formulations provide for more sustained controlled release of sunitinib or its analog or a pharmaceutically acceptable salt thereof. Increased loading is achieved using an alkaline solvent system. The pharmaceutical compositions can be administered to treat or prevent a disease or disorder in or on the eye of a patient associated with vascularization, such as corneal neovascularization and acute macular degeneration. Upon administration, the sunitinib or its analog or salt is released over an extended period of time at concentrations which are high enough to produce therapeutic benefit, but low enough to avoid unacceptable levels of cytotoxicity.

Abstract: A dual pass heat exchanger for cooling and dehumidifying an airstream has adjacent passes for air flow in which air flow is in opposite directions being counter-flow and parallel-flow passes. A cooling coil contains flowing chilled liquid refrigerant extending through all of the passes, and the coiling coil has fins on outer surfaces thereof for promoting efficient thermal transfer, whereby density of the fins in the counter-flow passes is greater than density in the parallel-flow passes, whereby fin density is varied in fin style, locational density, thickness and/or depth.

Abstract: Elongated, smaller-diameter tube heat pipes have an airflow arrangement that allows for short distances between evaporating and condensing sections of the heat pipe. The heat pipe is exposed to multiple alternate hot and cold zones adjacent to each other. Each evaporator zone accepts input heat to cause evaporation of the working fluid in the wick of the immediate vicinity. The vapor produced moves to either side by local pressure differences to condense in the two adjacent condenser zones where it is absorbed by the wick as a liquid and flows in the wick back to adjacent evaporator zones at each side. Each evaporator zone creates two fluid loops whereby evaporated working fluid splits up left and right, condenses in adjacent condenser zones and flows back to the evaporator zone as a liquid within the wick. Therefore, the overall tube length can be increased indefinitely, without traditional degradation of performance.

Abstract: Methods for increasing the encapsulation or incorporation of Sunitinib into polymeric matrices have been developed. The resulting formulations provide for more sustained controlled release of sunitinib or its analog or a pharmaceutically acceptable salt thereof. Increased loading is achieved using an alkaline solvent system. The pharmaceutical compositions can be administered to treat or prevent a disease or disorder in or on the eye of a patient associated with vascularization, such as corneal neovascularization and acute macular degeneration. Upon administration, the sunitinib or its analog or salt is released over an extended period of time at concentrations which are high enough to produce therapeutic benefit, but low enough to avoid unacceptable levels of cytotoxicity.

Abstract: A dual pass heat exchanger for cooling and dehumidifying an airstream has adjacent passes for air flow in which air flow is in opposite directions being counter-flow and parallel-flow passes. A cooling coil contains flowing chilled liquid refrigerant extending through all of the passes, and the coiling coil has fins on outer surfaces thereof for promoting efficient thermal transfer, whereby density of the fins in the counter-flow passes is greater than density in the parallel-flow passes, whereby fin density is varied in fin style, locational density, thickness and/or depth.

Abstract: A low temperature cooling and dehumidification system uses a reverse airflow arrangement to defrost a frosted cooling coil while not interrupting operation. Automatic air dampers are used to reverse the airflow at the proper time to initiate defrost of that section of frosted cooling coil. This system is useful for low temperature cooling and dehumidification in situations where the inlet air is above freezing, however exiting air below freezing can be supplied if desired. It is advantageous for operation if the coolant flow and temperature internal to the cooling coil are regulated to create the conditions for frost formation to begin closer to the air leaving side of the active cooling coil. The dehumidified generated condensate can be collected and used as grey water and/or potable water.

Abstract: Elongated, smaller-diameter tube heat pipes have an airflow arrangement that allows for short distances between evaporating and condensing sections of the heat pipe. The heat pipe is exposed to multiple alternate hot and cold zones adjacent to each other. Each evaporator zone accepts input heat to cause evaporation of the working fluid in the wick of the immediate vicinity. The vapor produced moves to either side by local pressure differences to condense in the two adjacent condenser zones where it is absorbed by the wick as a liquid and flows in the wick back to adjacent evaporator zones at each side. Each evaporator zone creates two fluid loops whereby evaporated working fluid splits up left and right, condenses in adjacent condenser zones and flows back to the evaporator zone as a liquid within the wick. Therefore, the overall tube length can be increased indefinitely, without traditional degradation of performance.

Abstract: A low temperature cooling and dehumidification system uses a reverse airflow arrangement to defrost a frosted cooling coil while not interrupting operation. Automatic air dampers are used to reverse the airflow at the proper time to initiate defrost of that section of frosted cooling coil. This system is useful for low temperature cooling and dehumidification in situations where the inlet air is above freezing, however exiting air below freezing can be supplied if desired. It is advantageous for operation if the coolant flow and temperature internal to the cooling coil are regulated to create the conditions for frost formation to begin closer to the air leaving side of the active cooling coil.

Abstract: A low temperature cooling and dehumidification system uses a reverse airflow arrangement to defrost a frosted cooling coil while not interrupting operation. Automatic air dampers are used to reverse the airflow at the proper time to initiate defrost of that section of frosted cooling coil. This system is useful for low temperature cooling and dehumidification in situations where the inlet air is above freezing, however exiting air below freezing can be supplied if desired. It is advantageous for operation if the coolant flow and temperature internal to the cooling coil are regulated to create the conditions for frost formation to begin closer to the air leaving side of the active cooling coil.

Abstract: A low temperature cooling and dehumidification system uses a reverse airflow arrangement to defrost a frosted cooling coil while not interrupting operation. Automatic air dampers are used to reverse the airflow at the proper time to initiate defrost of that section of frosted cooling coil. This system is useful for low temperature cooling and dehumidification in situations where the inlet air is above freezing, however exiting air below freezing can be supplied if desired. It is advantageous for operation if the coolant flow and temperature internal to the cooling coil are regulated to create the conditions for frost formation to begin closer to the air leaving side of the active cooling coil. The dehumidified generated condensate can be collected and used as grey water and/or potable water.

Abstract: An insertable, removable cooling coil in a heat exchange unit includes a heat exchange housing and one or more cooling coils in a heat exchange assembly in the housing. The housing is a pre-assembled housing having one or more respective recesses for insertion or removal of each respective cooling coil of the one or more cooling coils therein. Each cooling coil is slidably insertable upon side angle profile supports within the respective recesses of the heat exchange housing.

Abstract: A combination modular drain pan and horizontally positioned cooling coil assembly, providing dual pass dehumidification, including a housing, a plurality of adjacent discrete horizontal cooling coils each receiving air from an air distribution manifold. The air distribution manifold receives air from a inlet air stream and forming a single large horizontally positioned cooling coil module assembly. Each discrete horizontal cooling coil has a respective heat exchange area directly thereabove and a drain pan therebelow.

Abstract: A modular drain pan assembly with one-piece construction, having no seams in the condensate collection area and using multiple small drain pans with drip caps to avoid leakage between individual pans.

Abstract: Elongated, smaller-diameter tube heat pipes have an airflow arrangement that allows for short distances between evaporating and condensing sections of the heat pipe. The heat pipe is exposed to multiple alternate hot and cold zones adjacent to each other. Each evaporator zone accepts input heat to cause evaporation of the working fluid in the wick of the immediate vicinity. The vapor produced moves to either side by local pressure differences to condense in the two adjacent condenser zones where it is absorbed by the wick as a liquid and flows in the wick back to adjacent evaporator zones at each side. Each evaporator zone creates two fluid loops whereby evaporated working fluid splits up left and right, condenses in adjacent condenser zones and flows back to the evaporator zone as a liquid within the wick. Therefore, the overall tube length can be increased indefinitely, without traditional degradation of performance.

Abstract: An insertable, removable cooling coil in a heat exchange unit includes a heat exchange housing and one or more cooling coils in a heat exchange assembly in the housing. The housing is a pre-assembled housing having one or more respective recesses for insertion or removal of each respective cooling coil of the one or more cooling coils therein. Each cooling coil is slidably insertable upon side angle profile supports within the respective recesses of the heat exchange housing.

Abstract: An adjustable torque limiter that can be coupled between a high speed driver and the socket that rotates a mechanical fastener. When a preset torque level is reached, the torque limiter disengages the rotational drive force from the bit. The adjustability of the torque limitation is accomplished by varying the amount of spring force by which a thrust plate (coupled to the high speed driver) is forced against a set of steel balls residing in slots of a radial torque plate and in a set of paths formed in a concavity of an upper torque body (coupled to the driven socket engaging stud). When a certain preset torque is transmitted from the driver to the socket, the steel balls traverse outward along the separate arced ramp radial paths therein the upper torque body until the balls enter an annular race that allows the thrust plate to go into a disengaged or free wheel mode from the upper torque body.