Abstract: Provided is a system for engineering geomechanical experimental testing of a reservoir rock mass, including a stress control unit, a temperature control unit and a rock sample holder. The stress control unit includes a rigid pressure-applying mechanism and a flexible pressure-applying mechanism. The rigid pressure-applying mechanism is configured to apply rigid pressure to a rock mass via an indenter and a pressing piece. The flexible pressure-applying mechanism is configured to apply flexible pressure to the rock mass by using a pressure medium. Rigid pressure application and flexible pressure application are integrated to simulate a stress status under an actual geological condition better, and uniformity of pressure application is also ensured. The temperature control unit is configured to control a temperature of the rock mass via a heating mechanism and a cooling mechanism. A method for engineering geomechanical experimental testing of a reservoir rock mass is further provided.

Abstract: The present application provides GPC2-specific antibodies and antigen binding fragments thereof. A chimeric antigen receptor (CAR) that specifically binds glypican-2 (GPC2) comprising a GPC2-specific antibody, a transmembrane domain, and an intracellular signaling domain. T cells comprising the disclosed CAR constructs can be used for cancer immunotherapy.

Abstract: A track light, including a track, a lamp and latch structures connecting the track and the lamp. Each latch structure comprises a latch member, a connection member, a gasket and a locking member. The lamp is provided with mounting portions and mounting holes penetrating through the mounting portions. The connection members penetrate through the mounting holes and extend out of the lower surfaces of the mounting portions. The locking members are inserted from bottom to top into the connection members and are locked to be fixed to the tail ends of the connection members. The gaskets are sleeved on the outer side of the tail ends of connection members and are pressed to be fixed between the lower surfaces of the mounting portions and the locking members. The connection members are configured to penetrate through the mounting holes and then extend out of the lower surfaces of the mounting portions.

Abstract: Provided herein are anti-DLL3 chimeric antigen receptors (CARs), DLL3 binding proteins and uses of such CARs or DLL3 binding proteins in the treatment of DLL3 associated disorders, such as small cell lung cancer.

Abstract: This application discloses an electrode plate rolling apparatus and an electrode plate rolling method that are configured to roll an electrode plate. The electrode plate includes a coated region and an uncoated region. The electrode plate rolling apparatus includes a roller group, a heating part, and a cooling part. The heating part is configured to heat the electrode plate, and the cooling part is configured to cool the electrode plate. The heating part further includes an extension assembly, and the extension assembly can extend the uncoated region when the heating part heats the electrode plate. The electrode plate passes through the cooling part after passing through the heating part. The heating part and the cooling part are configured to reduce a difference between an extensibility parameter of the uncoated region and an extensibility parameter of the coated region.

Abstract: A current sampling circuit for a multi-level DC-DC converter having first and second power switches connected in series, and a first inductor having one terminal coupled to a common node of the first and second power switches, where the current sampling circuit is configured to: receive a first signal representing a current flowing through the first power switch; receive a second signal representing a current flowing through the second power switch; and generate a third signal representing an inductor current flowing through the first inductor according to the first signal and the second signal.

Abstract: A computer implemented method for certifying robustness of image classification in a neural network is provided. The method includes initializing a neural network model. The neural network model includes a problem space and a decision boundary. A processor receives a data set of images, image labels, and a perturbation schedule. Images are drawn from the data set in the problem space. A distance from the decision boundary is determined for the images in the problem space. A re-weighting value is applied to the images. A modified perturbation magnitude is applied to the images. A total loss function for the images in the problem space is determined using the re-weighting value. A confidence level of the classification of the images in the data set is evaluated for certifiable robustness.

Abstract: The present disclosure provides a water-soluble 1,3-diphenylguanidine (DPG)-based supramolecular inclusion complex and a preparation method and use thereof. A supramolecular compound and a vulcanization accelerator DPG are subjected to supramolecular interaction to form a DPG-based supramolecular inclusion complex. While improving water solubility and dispersibility of the DPG, a molecular structure of the DPG can be completely retained, and the supramolecular host used does not affect a performance of latex. The supramolecular compound and the DPG are ball milled in a certain proportion to prepare the DPG-based supramolecular inclusion complex, the water-soluble DPG-based supramolecular inclusion complex is added in a natural latex curing process; and after mixing evenly, a mixture is foamed on-machine, vulcanized in a steamer, and dried to obtain a latex foam product.

Abstract: A shear box for testing shear-seepage coupling characteristics of rock mass, and a method of using the shear box are provided, including an upper fixed shear box, and a lower movable shear box. A first extrusion block and an upper rock mass sample are arranged in a first placement groove of the upper fixed shear box. A second extrusion block and a lower rock mass sample are arranged in a second placement groove of the lower fixed shear box. A first elastic sealing member is arranged on each of both sides of the upper rock mass sample and the lower rock mass sample, and an elastic capsule is arranged on each of inner walls of both sides of the first placement groove and the second placement groove. An upper pressure head device for applying a force in a third direction is arranged on the upper fixed shear box.

Abstract: Provided is a sample fixture for an indirect tensile test of rock mass, relating to the technical field of rock mass engineering geomechanics tests. The sample fixture includes an upper fixture, and a lower fixture located below the upper fixture. The upper fixture includes an upper fixing block, a ball head, and an upper knife. The lower fixture includes a lower fixing block, a telescopic positioning plate, and a lower knife. The ball head is in fit with a spherical groove on an upper surface of the upper fixing block to achieve the function of transferring pressure, thus ensuring loading strength acting on a sample. A loading force is transferred by using a cutting edge of the upper knife to make the pressure act on the sample intensively, thus ensuring point or linear loading required by the test.

Abstract: There is provided a solution for advantage generation. In the solution, a value model is pretrained based on respective returns for respective first tokens in a first response of a plurality of first responses output by a trained reference model. A return for a first token indicates a cumulative reward from the first token to an end of the first response. Respective advantages for respective second tokens in a second response of a plurality of second responses output by a language model are generated based on the pretrained value model. An advantage for a second token indicates a cumulative reward for the second token relative to an average of cumulative rewards for candidate tokens at a position of the second token.

Abstract: A method and system for monitoring structural deterioration of a reservoir rock mass under a long-time high-temperature condition, and a product are provided. The method includes: arranging ultrasonic transducers and fiber optic extrinsic Fabry-Perot interferometric (EFPI) sensors in a loading briquette; loading ultrasonic waves on a rock mass sample with the ultrasonic transducers; monitoring ultrasonic and acoustic emission signals at the rock mass sample with the fiber optic EFPI sensors; inverting a velocity model indicating a change of a wave velocity inside the rock mass sample over time by fast marching acoustic emission tomography using standard optimization (FaATSO) according to the ultrasonic and acoustic emission signals; and conducting joint inversion by a fast-marching method according to the velocity model, the acoustic emission signals, and observation data to determine a position of rock mass fracturing in the rock mass sample.

Abstract: Provided herein are anti-DLL3 chimeric antigen receptors (CARs), DLL3 binding proteins and uses of such CARs or DLL3 binding proteins in the treatment of DLL3 associated disorders, such as small cell lung cancer.

Abstract: A track light belongs to the field of lighting technology is provided. The track light includes a track, and a lamp in electrical contact with the track, the lamp includes a substrate, an elastic structure, and a power obtain structure plugged and fixed on the substrate, the substrate is provided with a through hole, the elastic structure includes a mounting post and an elastic portion, the mounting post is accommodated in the through hole and is in contact with an inner wall of the through hole, a power transmission strip is provided in the track, the power obtain structure includes an abutment portion in electrical contact with the power transmission strip, the elastic portion is provided between the abutment portion and the substrate to generate elastic deformation in response to that the abutment portion and the power transmission strip are pressed against each other.

Abstract: A method of controlling a three-level DC-DC converter having first, second, third, and fourth power switches coupled in series between an input voltage and a reference ground, and a flying capacitor coupled between a common node of the first and second power switches and a common node of the third and fourth power switches, can include: operating the flying capacitor in a first mode in which the voltage across the flying capacitor is controlled to not be decreased in at least two consecutive first intervals, where each first interval is half of a switching period of the three-level DC-DC converter; and operating the flying capacitor in a second mode in which the voltage across the flying capacitor is controlled not to be increased in at least two consecutive first intervals, such that the voltage across the flying capacitor approaches a predetermined value.

Abstract: A track light, including a track, a lamp and latch structures connecting the track and the lamp. Each latch structure comprises a latch member, a connection member, a gasket and a locking member. The lamp is provided with mounting portions and mounting holes penetrating through the mounting portions. The connection members penetrate through the mounting holes and extend out of the lower surfaces of the mounting portions. The locking members are inserted from bottom to top into the connection members and are locked to be fixed to the tail ends of the connection members. The gaskets are sleeved on the outer side of the tail ends of connection members and are pressed to be fixed between the lower surfaces of the mounting portions and the locking members. The connection members are configured to penetrate through the mounting holes and then extend out of the lower surfaces of the mounting portions.

Abstract: A track lamp is provided, which includes a track and an electrical connection device in electrical contact with the track, in which the electrical connection device includes a substrate, a power supply structure plugged and fixed on the substrate, and an elastic member arranged between the substrate and the power supply structure, the power supply structure is provided with a convex portion, to be in electrical contact with a power transmission bar in the track; and the elastic member is configured to generate elastic deformation in a case that the convex portion and the power transmission bar are pressed against each other, so that the convex portion and the power transmission bar are kept abutting against with each other.

Abstract: A real-time quantitative characterization method, equipment and a medium for rock mass evolution are disclosed. The method includes: the multiphase field detection and monitoring data is fused; a deep learning model driven by physical principles is established based on the physical principles of fluid density; the deep learning model is trained using real-time fused data as input and corresponding evolution distribution images as output; a trained deep learning model is used to obtain an evolution distribution image based on multi-phase field detection and monitoring data of different time periods and types; a mathematical model is used to quantitatively characterize of physical and mechanical parameters in the whole process of progressive failure of the dynamic evolution of the rock mass based on the macroscopic mechanical parameters and evolution distribution images synchronized with multiphase field detection and monitoring data.

Abstract: A double-track welding system is provided. A first track is detachably mounted on a first side of a weld seam of a workpiece, and a second track is detachably mounted on a second side of the weld seam of the workpiece. The first track and the second track are both mounted on a fixed support, and the fixed support can drive the first track and second track to move. At least one welding trolley is arranged on each of the first track and the second track. An image acquisition component is used for acquiring an image of a part to be welded; a weld seam scanning device is used for acquiring the weld seam morphology; and a control system is used for controlling, according to the image of the part to be welded, the fixed support to move.

Abstract: A control circuit of a three-level DC-DC converter, can include where: the three-level DC-DC converter includes first, second, third, and fourth power switches coupled in series between an input voltage and a reference ground, and a flying capacitor coupled between a common node of the first and second power switches and a common node of the third and fourth power switches; and the control circuit is configured to adjust a phase difference between driving signals of the first and second power switches, and duty ratios of the first and second power switches, according to an error between a voltage across the flying capacitor and a predetermined value, such that the voltage across the flying capacitor is stabilized at the predetermined value.