Abstract: An integrated circuit can include: a bottom structure; at least one GaN transistor die, where each GaN transistor die includes at least one power switching device; a silicon die including a control circuit for controlling the power switching device; and where the GaN transistor die and the silicon die are arranged on the bottom structure, and an electrical connection between the control circuit and the power switching device includes corresponding patterned metal structures arranged in the bottom structure.

Abstract: A switched capacitor converter can include a plurality of input switch groups connected in series between an input terminal and an output terminal, where each input switch group can include two power switches connected in series. The switched capacitor converter can also include a plurality of output switch groups, where each output switch group can include two power switches connected in series. The switched capacitor converter can also include a plurality of capacitors, first terminals of which are respectively connected to the common nodes of every two series-connected power switches in the plurality of input switch groups, and second terminals of which are respectively connected to intermediate nodes of each output switch group. The switched capacitor converter can also include a plurality of inductors, where a first terminal of each output switch group can connect to a first terminal of a corresponding inductor.

Abstract: An intelligent modeling method of a Selective Catalytic Reduction (SCR) reaction process of diesel vehicle exhaust includes the following steps: S1: acquiring a time sequence data set of an SCR reaction process of diesel vehicle exhaust for modeling, where the time sequence data set includes an input variable sequence and an output variable sequence; S2: selecting a multi-layer type-II fuzzy neural network as an SCR reaction process model of diesel vehicle exhaust based on the input variable sequence and the output variable sequence obtained in Si. The intelligent modeling method of the SCR reaction process of diesel vehicle exhaust can effectively model dynamic characteristics of the SCR reaction process such as nonlinearity, time delay and uncertain interference, and improve the accuracy, robustness and generalization ability of the SCR reaction process model.

Abstract: Obtain, using at least one hardware processor, data characterizing a physical system governed by a physical conservation law. Apply, using the at least one hardware processor, contrastive learning to the data to automatically capture system invariants of the physical system. Employ, using the at least one hardware processor, a neural projection layer to guarantee that a corresponding dynamic machine learning model preserves the captured system invariants. Optionally, predict performance of the physical system using the corresponding dynamic machine learning model.

Abstract: A step-down circuit, an electronic device, and a step-down method are disclosed. The step-down circuit includes a positive input terminal and a negative input terminal for receiving an input voltage; and a positive output terminal and a negative output terminal for outputting a target voltage. The negative input terminal and the negative output terminal are grounded together. The step-down circuit also includes a switch circuit, a rectifier circuit, an isolation circuit, and a control unit for outputting control signals to control for turning on or off a switch in the switch circuit and for turning on or off a switch in the rectifier circuit, allowing the input voltage to sequentially pass through the switch in the switch circuit, a capacitor in the isolation circuit, and the switch in the rectifier circuit to obtain a target voltage.

Abstract: An organic electroluminescent display panel, a method of manufacturing the same, and a display device that can alleviate or avoid the occurrence of pixel crosstalk problems due to lateral conduction of the charge generation layer are disclosed. An organic electroluminescent display panel is provided which comprises: a substrate; an anode layer and a pixel defining layer over the substrate, the pixel defining layer defining pixel units, wherein a recess is provided in the pixel defining layer between adjacent pixel units; a stack of organic electroluminescent units over the anode layer and the pixel defining layer, the stack comprising at least two organic electroluminescent units and a charge generation layer disposed between organic electroluminescent units which are adjacent to each other; a cathode layer over the stack. The corresponding charge generation layers of the adjacent pixel units are disconnected at the recesses. The cathode layer is continuous at the recess.

Abstract: A technique for providing real time feedback from a machine learning system is provided that includes a method and system for interactively training machine learning models. In particular, by separating processing and analysis using static and dynamic models that are trained differently, the disclosed technique enables interactive training and prediction of machine learning models to increase the speed of generating new predictions based on real time feedback. In some cases, a dynamic model is applied to the output of a static model to generate an analysis, a correction of the analysis is received, and the correction is used to retrain the dynamic model. An updated analysis is generated based on reapplying the dynamic model to the output of the static model without having to retrain the static model.

Abstract: Provided are a mixing impeller and pulping device. The mixing impeller includes an impeller body, the impeller body defines, at a bottom end of the impeller body, a cavity extending to a top end of the impeller body, and the impeller body defines an overflow hole in communication with the cavity at a side wall of the impeller body.

Abstract: Provided are single-domain antibodies targeting CLL1 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune effector cells (such as T cells) comprising an anti-CLL1 chimeric receptor and optionally a second chimeric receptor targeting a second antigen or epitope. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

Abstract: The disclosure belongs to the technical field of capsule robotics, and in particular, relates to a magnetically driven capsule robot with controllable drug administration and sampling functions and a fabrication method thereof. A magnetically driven capsule robot provided by the disclosure includes a robot body and a magnetic field-driven control module. The robot body includes a capsule shell, two ends of the capsule shell are provided with hollow air chambers, and a carrier chamber is disposed between the hollow air chambers disposed on the two ends. A substance transfer channel, a magnetic lock disposed around the substance transfer channel, and a magnetic soft switch valve matched with the magnetic lock are disposed on a side wall of the carrier chamber. The soft valve automatically closes due to the magnetic attraction force between the lock and valve, and can be flexibly opened under a magnetic torque acting on the valve.

Abstract: A power conversion module can include: an i-th level structure comprising 2i-1 basic units, a second terminal of each basic unit in each level structure respectively connected to first terminals of two basic units in a next level structure, where a first terminal of a first basic unit in a first-level structure is used as a first terminal of the power conversion module; an N-th level structure comprising 2N-1 balance units, where second terminals of each balance unit are connected as a second terminal of the power conversion module, and second terminals of each basic unit in an (N?1)th level structure are respectively connected to first terminals of two balance units in the N-th level structure; and where each basic unit comprises a switched capacitor circuit, N is a positive integer greater than or equal to 2, i is a positive integer, and 1?i?N?1.

Abstract: The present disclosure provides a water-soluble 1,3-diphenylguanidine (DPG)-based supramolecular inclusion complex and a preparation method and use thereof. A supramolecular compound and a vulcanization accelerator DPG are subjected to supramolecular interaction to form a DPG-based supramolecular inclusion complex. While improving water solubility and dispersibility of the DPG, a molecular structure of the DPG can be completely retained, and the supramolecular host used does not affect a performance of latex. The supramolecular compound and the DPG are ball milled in a certain proportion to prepare the DPG-based supramolecular inclusion complex, the water-soluble DPG-based supramolecular inclusion complex is added in a natural latex curing process; and after mixing evenly, a mixture is foamed on-machine, vulcanized in a steamer, and dried to obtain a latex foam product.

Abstract: One or more computer processors create a fully convolution network (FCN) comprising a plurality of 1×1 convolutions. The one or more computer processors append linear mapping layer (LM) to created FCN. The one or more computer processors capture a plurality of features utilizing multi-scale dilated convolutional kernels from the linear mapped FCN (LM-FCN). The one or more computer processors apply an average pool layer to the captured plurality of features along a temporal axis of a dilated convolutional kernel within the LM-FCN. The one or more computer processors predict a classification for subsequent time-series data utilizing the pooled plurality of features.

Abstract: A power converter can include: a plurality of circuit modules coupled in parallel between a first port and a second port, where each of the plurality of circuit modules includes a switching power stage circuit having a first magnetic element coupled between a switch node of the switching power stage circuit and a first terminal of the second port, at least one switch group having first and second transistors and being coupled between a first terminal of the first port and a first terminal of the switching power stage circuit, and at least one first energy storage capacitor for providing energy to a load of the power converter; and a plurality of second energy storage capacitors configured to periodically store energy and release energy to corresponding first energy storage capacitors.

Abstract: The present application discloses a gravimeter zero-drift correction method, apparatus and electronic device, which belongs to the field of gravimeter correction. The gravimeter zero-drift correction method includes: acquiring standard comparison data and actual monitoring data of the gravimeter; determining a plurality of difference values between the actual monitoring data and the standard comparison data; determining the presence or absence of an inflection point among a plurality of difference values; correcting a plurality of difference values in the absence of inflection point among a plurality of difference values; correcting difference values on both sides of a demarcation point respectively by taking an infection point as a demarcation point, in the presence of an inflection point among a plurality of difference values.

Abstract: Providing a trained reinforcement learning (RL) model by formulating a decision process problem for the RL model, defining at least one of a logarithmic loss function for the RL model and defining an initiation point for the RL model according to an optimized spectral norm of the RL model, training the system according to the logarithmic loss function or from the initiation point, and providing the trained RL model.

Abstract: The present disclosure provides immune effector cells engineered to express a functional exogenous receptor such as a CAR armored with a tumor homing peptide. The immune effector cells according to the present disclosure have enhanced tumor infiltration and anti-tumor efficacy.

Abstract: Provided is a fusion protein dimer using an antibody Fc region as the backbone, comprising a first and a second polypeptide chain. The first polypeptide chain comprises a first antibody Fc region and one or more single-domain antibodies fused to the first antibody Fc region. The second polypeptide chain comprises a second antibody Fc region and one or more single domain antibodies fused to the second antibody Fc region. The first polypeptide chain and/or the second polypeptide chain further comprise a cytokine fused to the Fc region of the respective antibody. Further provided is use of the fusion protein dimer in preparing an immunotherapeutic drug for treating tumors. The Fc fusion protein heterodimer not only increases the activity of a single domain antibody, but also significantly improves the biological activity of a cytokine.

Abstract: The present application discloses a gravimeter zero-drift correction method, apparatus and electronic device, which belongs to the field of gravimeter correction. The gravimeter zero-drift correction method includes: acquiring standard comparison data and actual monitoring data of the gravimeter; determining a plurality of difference values between the actual monitoring data and the standard comparison data; determining the presence or absence of an inflection point among a plurality of difference values; correcting a plurality of difference values in the absence of inflection point among a plurality of difference values; correcting difference values on both sides of a demarcation point respectively by taking an infection point as a demarcation point, in the presence of an inflection point among a plurality of difference values.

Abstract: The present application provides constructs comprising a single-domain antibody (sdAb) moiety that specifically recognizes TIGIT. Also provided are methods of making and using these constructs.