Abstract: The present invention is to provide methods and devices that monitoring health and diagnosing a disease by directly measuring the biomarkers inside a cell (intra-cellular detection) rapidly and easily.

Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that is unavailable in using a single sample thickness.

Abstract: Embodiments relate to a modified cell comprising a polynucleotide encoding a dominant negative form of Death receptor 5 (DR5). In embodiments, the modified cell further comprises a chimeric antigen receptor (CAR) and/or a modified TCR.

Abstract: Disclosed is a method to fabricate a multifunctional collimator structure In one embodiment, an optical collimator, includes: a dielectric layer; a substrate; and a plurality of via holes, wherein the dielectric layer is formed over the substrate, wherein the plurality of via holes are configured as an array along a lateral direction of a first surface of the dielectric layer, wherein each of the plurality of via holes extends through the dielectric layer and the substrate from the first surface of the dielectric layer to a second surface of the substrate in a vertical direction, wherein the substrate has a bulk impurity doping concentration equal to or greater than 1×1019 per cubic centimeter (cm?3) and a first thickness, and wherein the bulk impurity doping concentration and the first thickness of the substrate are configured so as to allow the optical collimator to filter light in a range of wavelengths.

Abstract: Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.

Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that are unavailable in using a single sample thickness.

Abstract: Disclosed is an apparatus and method for imaging: a side-view of a object on a surface, a Contact Angle of a liquid object, the color of an object, or combinations thereof.

Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.

Abstract: A multiplex assay device including: a separation structure on a first plate; and a sample contact area on the surface of the first plate. Also disclosed is a method for fabricating a multiplex assay, including: making a reagent into a non-liquid reagent particle; creating a well on a sample contact area of a plate of a Q-card two plate sample card; and dropping one or more of the non-liquid reagent particles into at least one well.

Abstract: The present invention is related to, among other things, the devices and methods that improve the accuracy and reliability of an assay, even when the assay device and/or the operation of the assay device has certain errors, and in some embodiments the errors are random.

Abstract: The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allows a test performed by a smartphone.

Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.

Abstract: Methods for generating automations via natural language processing are performed by computing systems. Natural language input is received from a user interface, and an automation workflow is generated based on the natural language input. The automation workflow includes steps to build an automation. One or more of the steps is provided to the user interface, and a first field and a second field that each correspond to the one or more steps are populated in the user interface. The first field is populated with a parameter value based on the natural language input, and the second field is populated based on the parameter value. The automation is then enabled to be built and deployed.

Abstract: Methods, systems, and computer program products are described herein for implementing a workflow development system that includes automatic code generation for data transformations. For instance, the workflow development system may provide a graphical user interface that enables a user to add and/or configure one or more workflow steps. At least one workflow step may be configured to perform a transformation or re-formatting of data that may be received from a previous workflow step. The code utilized to perform the transformation or re-formatting may be automatically determined by the workflow development system in accordance with programming-by-example techniques, where a user provides sample input data representative of the data prior to transformation and provides sample output data representative of data post-transformation. The workflow development system learns and/or generates code, that is able to perform the transformation as desired by the user, based on the sample input and output data.

Abstract: The present disclosure describes storage techniques for hybrid transactional and analytical processing. Data captured by a first processing engine may be received. The first processing engine may be configured to perform online transactional processing). Multiple replicas of logical logs generated based on the data may be distributed to a Delta Store by applying a quorum protocol on the multiple replicas. Data in the Delta Store are stored in a row format and are visible to a query for online analytical processing performed by a second processing engine. Data may be flushed from the Delta Store to a Base Store based on one or more predetermined rules. Data in the Base Store are stored in a columnar format and may be accessible by the second processing engine.

Abstract: One aspect of the present invention is to provide systems and methods that improve the accuracy of an assay that comprise at least one or more parameters each having a random error.

Abstract: Disclosed is a cost-effective method to fabricate a multifunctional collimator structure for contact image sensors to filter ambient infrared light to reduce noises. In one embodiment, an optical collimator, includes: a dielectric layer; a substrate; a plurality of via holes; and a conductive layer, wherein the dielectric layer is formed over the substrate, wherein the plurality of via holes are configured as an array along a lateral direction of a first surface of the dielectric layer, wherein each of the plurality of via holes extends through the dielectric layer and the substrate from the first surface of the dielectric layer to a second surface of the substrate in a vertical direction.

Abstract: Among other things, the present disclosure is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly a homogeneous assay that does not use a wash step and that is fast (e.g., 60 seconds from dropping a sample to displaying results). The present disclosure is related to both competitive and non-competitive homogeneous assays.

Abstract: Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.