Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt thereof, and/or solvates racemic mixtures, enantiomers, diasteromers, and tautomers thereof, wherein A, R1, R2, R3, R3?, R4, R4?, R5, R6, R7, R8, m, and n are as defined in the detailed description.

Abstract: Various apparatuses, systems, methods, and media are disclosed to provide a heat-assisted magnetic recording (HAMR) medium that includes a sacrificial layer and corresponding etching processes to minimize head to media spacing. The medium may include the sacrificial layer and a capping layer where each of the layers is etched to reduce roughness. The sacrificial layer is configured to ensure an etch rate that allows for selective etching and may be deposited on the capping layer and after etching, may remain along grain boundaries of the capping layer. The remaining portions of the sacrificial layer may form a discontinuous layer, including layer segments positioned along grain boundaries of the capping layer. The sacrificial layer may be made of non-magnetic materials different from the materials of the capping layer or materials of an overcoat layer deposited on the etched capping layer.

Abstract: An end-effector configured to grasp tissue is disclosed herein. The end-effector includes an ultrasonic blade configured to transfer ultrasonic energy to the tissue and a clamp arm. The clamp arm includes a clamp arm pad including an electrically conductive material and an electrically non-conductive material. The clamp arm pad is configured as an electrode of a radiofrequency energy circuit, wherein the electrode is configured to transfer radiofrequency energy through the tissue to a return electrode of the radiofrequency energy circuit, and wherein the electrically non-conductive material is configured to reduce the possibility of an electrical short between the electrically conductive material and the ultrasonic blade as the clamp arm pad degrades throughout the usable life of the end effector.

Abstract: Disclosed is a surgical instrument with an end-effector adapted and configured to deliver a plurality of energy modalities to tissue at a distal end thereof. The energy modalities may be applied simultaneously, independently, or sequentially. A generator is electrically coupled to the surgical instrument and is configured to supply a plurality of energy modalities to the end-effector. In one aspect, the generator is configured to supply electrosurgical energy (e.g., monopolar or bipolar radio frequency (RF) energy) and ultrasonic energy to the end-effector to allow the end-effector to interact with the tissue. The energy modalities may be supplied to the end-effector by a single generator or multiple generators.

Abstract: The present disclosure provides a self-generating heat process for in-situ converting medium-low mature and organic-rich shale, and relates to the field of in-situ mining of medium-low mature shale rich in organic matter, the self-generating heat process mainly comprises the following steps: locally preheating the vincinity of an injection well of medium-low mature and organic-rich shale formation with well-reformed reservoir and injecting ambient temperature air into the preheated formation to excite and establish a chemical reaction zone composed of a residue zone, an autogenous heat zone, a thermal cracking zone and a preheating zone. Heat is released by oxidation reaction of residues generated after kerogen thermal cracking, so as to realize convection heating of medium-low mature and organic-rich shale formation. Oil and gas products generated from kerogen thermal cracking enter production wells through fractures and are lifted to the ground surface.

Abstract: The present invention provides simple methods of making free-flowing surface modified particles that enhance the functionality of surface modified particles containing them. The methods comprise treating finely divided dry or anhydrous particles, with an activator to form activated particles, mixing the activated particles with a stabilized aqueous composition comprising at least one polymer, such as one containing an additional ingredient, such as an antioxidant, an antimicrobial, an adhesion promoter, one or more colorants, one or more pigments, fillers or extenders, an abrasion resistant polymer, or a waterproofing agent to form a moist mixture; and, drying the moist mixture until it forms free-flowing surface modified particles, each particle having one or more discrete deposits of the polymer as solids on its surface.

Abstract: A pluggable module includes a power control unit, an interface unit, a monitoring unit, and a signal linkage unit. The power control unit is connected to the interface unit, and the pluggable module can be inserted into an external device by using the interface unit. One end of a pull ring is rotatably connected to a bracket, and the other end can trigger a signal switch. When the pull ring is in an ON state, the signal switch is triggered to send a first switch signal, or when the pull ring is in an OFF state, the signal switch sends a second switch signal. The monitoring unit is configured to control, upon receiving the first switch signal, the power control unit to be powered on, or control, upon receiving the second switch signal, the power control unit to be powered off.

Abstract: An item recommendation method includes obtaining N pieces of first information, where an ith piece of first information indicates an ith first item and an ith behavior, the ith behavior is a behavior of a user for the ith item, N behaviors of the user correspond to M categories, i=1, . . . , N, N?M, and M>1; processing the N pieces of first information based on a multi-head self-attention mechanism, to obtain N pieces of second information; and obtaining an item recommendation result based on the N pieces of second information, where the item recommendation result is used to determine, from K second items, a target item recommended to the user, and K?1.

Abstract: A method and apparatus for forming vascular-like channels involves liquid-in-liquid 3D printing utilizing two polymer solutions used as a printing ink and a matrix. Anionic polyacrylamide (APAM) is one of the polymer solutions and acts as the matrix material. Chitosan is the other polymer solution and acts as the printing ink. The chitosan printing ink is extruded through a print nozzle of a 3D printer onto the APAM matrix which covers the bottom of a petri dish while the nozzle is moved in a desired pattern for the channels. The chitosan and APAM polymer complexes self-assemble on the ink-matrix interface, locking chitosan polymers inside the matrix before they can spread and causing the formation of soft elastic membranous walls. The chitosan ink and APAM matrix can be removed after the polymer complex self-assembly. The printed chamber with membranous walls allows for liquid infusion to work as fluidic channels.

Abstract: The present disclosure provides a compound represented by structural formula (I0) or a pharmaceutically acceptable salt, or a stereoisomer thereof and their use in, e.g. treating a disease or disorder associated with the PAD4 activity. This disclosure also features compositions containing the same as well as methods of using and making the same.

Abstract: An electrical power supply designed to supply electrical power to an electrical power bus is presented herein. The electrical power supply comprises an electronic controller connected to a DC/DC converter and a current sensor for measuring the converter's current. The DC/DC converter is linked to a power conductor of the electrical power bus through a first switch and to a ground conductor through a second switch. The electronic controller is programmed to manage the first and second switches, disconnecting the DC/DC converter from the power bus when the current surpasses a predetermined threshold. This innovative system ensures efficient power management and protection against overcurrent situations in electrical power supply applications.

Abstract: Disclosed is an extensible electrode array (102) for accurately locating a pelvic floor muscle, and its design method and an extensible pelvic floor electrode.

Abstract: A device and method for regulating the release of adenosine in an organism, and the use thereof. The device comprises a stimulus generator for generating stimuli of a specific frequency. The use of the device of the present invention in an organism can effectively increase the concentration of adenosine in the brain of the organism, thereby providing an effective strategy for the improvement of sleep disorders.

Abstract: Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.

Abstract: Various apparatuses, systems, methods, and media are disclosed to provide a heat-assisted magnetic recording (HAMR) medium that includes a sacrificial layer and corresponding etching processes to minimize head to media spacing. The medium may include the sacrificial layer and a capping layer where each of the layers is etched to reduce roughness. The sacrificial layer is configured to ensure an etch rate that allows for selective etching and may be deposited on the capping layer and after etching, may remain along grain boundaries of the capping layer. The remaining portions of the sacrificial layer may form a discontinuous layer, including layer segments positioned along grain boundaries of the capping layer. The sacrificial layer may be made of non-magnetic materials different from the materials of the capping layer or materials of an overcoat layer deposited on the etched capping layer.

Abstract: Disclosed are a test system and a test method for a DRAM module of an INTEL system. The test system includes at least one memory module slot and a processing unit. When performing a test, a memory temperature sensing of a BIOS is turned off through an operating system. Then, an operation register in the INTEL central processing unit that has a function of connecting the DRAM module is detected, and a memory module transfer register determines whether the DRAM module is correctly plugged in. Then, the operation register accesses the EEPROM of the DRAM module, and writes test data to and reads the test data from the EEPROM by switching different storage pages of the EEPROM to complete the test.

Abstract: A device and a method of flattening recycled carbon fiber material are provided. A main body is provided with two flat plates at an upper and a lower positions corresponding to each other and an ultrasonic unit is disposed on each of the flat plates. While in use, recycled carbon fiber material is placed at the lower flat plate and then at least one ultrasonic probe of the ultrasonic unit is driven to work and vibrate the recycled carbon fiber material into a flat and thin state. After the flattened recycled carbon fiber material being pressurized to form products required, the product has flat and smooth surfaces with special textures. A thickness of the product can be controlled and the product can be thinned according to users' needs, without surface treatment such as grinding, polishing, etc. Thereby production cost is reduced and yield rate of the products is improved.

Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt thereof, and/or solvates racemic mixtures, enantiomers, diasteromers, and tautomers thereof, wherein A, R1, R2, R3, R3?, R4, R4?, R5, R6, R7, R8, m, and n are as defined in the detailed description.