Abstract: Providing heteraromatic compounds and uses thereof. In particular, providing heteraromatic compounds of formula (I), pharmaceutical compositions comprising same, methods for preparing same and uses thereof, wherein the variables are as defined in the description.

Abstract: It relates to zirconia particles containing molybdenum and each having a polyhedron shape. The molybdenum is preferably unevenly distributed in surface layers of the zirconia particles. It also relates to a method for producing the zirconia particles. The method includes mixing a zirconium compound and a molybdenum compound to form a mixture and firing the mixture.

Abstract: A hydraulic actuator with no friction and zero leakage and its drive system are provided. The hydraulic actuator includes a thickened disc structure A and a thickened disc structure B. The second end face of the thickened disc structure A is connected with the first end face of the thickened disc structure B, and a control cavity is formed between the second end face of the thickened disc structure A and the first end face of the thickened disc structure B. The drive oil access hole is arranged on the thickened disc structure B, and the control cavity is connected with the drive oil access hole. The displacement output method based on elastic deformation is adopted, which completely avoids the nonlinear phenomena such as leakage and friction, and reduces the difficulty of high-precision control of the actuator.

Abstract: An electronic cigarette atomizer and an electronic cigarette are disclosed. The electronic cigarette atomizer comprises an air inlet (1), an air inlet passage (2), an atomization cavity (3), an air outlet passage (4), an air outlet (5), and a suction nozzle (6) that are communicated in sequence. The electronic cigarette atomizer further comprises a housing (8) and an adjustment mechanism (7) for adjusting the air input of the air inlet (1). The air inlet passage (2), the atomization cavity (3), and the air outlet passage (4) are all arranged in the housing (8), and a top of the housing (8) is provided with a top cover (9). The adjustment mechanism (7) comprises a movable member (10) located in the top cover (9) and movable axially along the top cover (9).

Abstract: The present disclosure provides a blending method of high-quality and dual-purpose flour for bread and noodles, belonging to the technical field of flour processing. The method includes: selecting flour of a high-quality and dual-purpose wheat variety for bread and noodles as a high-quality basic flour for blending; according to a large gradient experimental design, selecting a gradient range ratio with a sedimentation value ?46.0 mL and a dough development time ?9.6 min, followed by subdividing for small gradient experiments; selecting a ratio with flour sedimentation value and dough development time that reach an ideal value to blend a large amount of flour; and making bread and noodles for scoring, followed by determining a blending ratio if a scoring result reaches an ideal value.

Abstract: A well cementing method is described for improving cementing quality by controlling the hydration heat of cement slurry. By controlling the degree and/or rate of hydration heat release from cement slurry, the method improves the hydration heat release during formation of cement with curing of cement slurry, improves the binding quality between the cement and the interfaces, and in turn improves the cementing quality at the open hole section and/or the overlap section. The cementing method improves cementing quality of oil and gas wells and reduces the risk of annular pressure.

Abstract: Aspects of the disclosure provide a semiconductor device. The semiconductor device includes a memory stack of gate layers and insulating layers. The gate layers and the insulating layers are stacked alternatingly and are formed into stair steps in a staircase region. The semiconductor device includes a first landing pad on a first gate layer of a first stair step. The first gate layer is a top gate layer of the first stair step. The semiconductor device further includes a first sidewall isolation structure on a riser sidewall of a second gate layer of a second stair step. The second gate layer is a top gate layer of the second stair step and is stacked on the first gate layer in the memory stack. The first sidewall isolation structure isolates the second gate layer from the first landing pad.

Abstract: A live broadcasting recording equipment, a live broadcasting recording system and a live broadcasting recording method are provided. The live broadcasting recording equipment includes a camera, a processing device, and a terminal device. The camera captures images to provide photographic data. The processing device executes background removal processing on the photographic data to generate a person image. The terminal device communicates with the processing device and has a display. The processing device executes multi-layer processing to fuse the person image, a three-dimensional virtual reality background image, an augmented reality object image, and a presentation image, and generate a composite image. After an application gateway of the processing device recognizes a login operation of the terminal device, the processing device outputs the composite image to the terminal device, so that the display of the terminal device displays the composite image.

Abstract: Embodiments of the present disclosure provide a message pushing method for a virtual gift and an electronic device. The method includes: when a virtual gift is received in a live broadcast room, determining a live broadcast room area to which a notification message is pushed, where the notification message is used to inform all live broadcast rooms in the live broadcast room area that the virtual gift is received; and pushing the notification message to the live broadcast room in the live broadcast room area respectively. The embodiments of the present disclosure implement rich methods for posting notification information about the receipt of the virtual gift, thereby improving user experience.

Abstract: Embodiments of the present disclosure relate to a permission setting method and apparatus, a device, and a medium. The method includes: displaying a permission customization control, in response to a trigger operation on a permission setting object of task information, the permission setting object including a first information object and/or a second information object, the second information object being subordinate to the first information object; displaying a permission editing interface, in response to a trigger operation on the permission customization control, and receiving customization permission information via the permission editing interface; and displaying the customization permission information corresponding to the permission setting object. Therefore, a hierarchy structure based on the task information satisfies a setting need for content-based permission customization, and improves a permission management efficiency.

Abstract: An example apparatus for generating synthesized images includes a receiver to receive a frame, a mask and external images. The apparatus also includes a foreground augmenter to generate augmented foregrounds in the frame based on the mask. The apparatus includes a background augmenter to generate augmented backgrounds based on the frame, the mask, and the external images. The apparatus also further includes an image synthesizer to generate a synthesized image based on the generated augmented foregrounds and the augmented backgrounds.

Abstract: A preparation method of a flexible polyurethane foam includes the following steps of: (1) subjecting an epoxidized vegetable oil, a benzoylformic acid, a basic catalyst, and an inert solvent to a ring-opening reaction in a first microchannel reactor of a microchannel reaction device to obtain a vegetable oil polyol; (2) subjecting the vegetable oil polyol obtained in the step (1), a propylene oxide and an inert solvent to an addition polymerization reaction in a second microchannel reactor of the microchannel reaction device to obtain a vegetable oil polyol for flexible polyurethane foam; and (3) using the vegetable oil polyol for flexible polyurethane foam obtained in the step (2) as the unique polyol, and subjecting the same and an isocyanate polyol to a foaming reaction to obtain the flexible polyurethane foam.

Abstract: Sessions in progress are seamlessly moved between devices of a software platform. Proximity-based session handovers are performed between devices of the software platform utilizing non-penetrating signals. The non-penetrating signals are detected by mobile devices. The non-penetrating signals include a frequency signature. The frequency signature is associated with a stationary device. A request to handover a session in progress from the mobile device to the stationary device is transmitted based on the detection of a non-penetrating signal. A handover of the session in progress from the mobile device to the stationary device is performed such that the session in progress is continued at the stationary device without interruption.

Abstract: An electronic cigarette atomization core and atomizer is disclosed. The electronic cigarette atomization core includes an atomization member (3), an outer sleeve (24), a connection sleeve (22), and atomization cotton (14). A lower segment of the connection sleeve (22) is sleeved outside an upper segment of the outer sleeve (24). The outer sleeve (24) is sleeved outside the atomization cotton (14). The outer sleeve (24) is provided with a first e-liquid passage hole (2401) capable of communicating an inner cavity of an electronic cigarette e-liquid bin (12) with the atomization cotton (14). The connection sleeve (22) is axially movable or circumferentially rotatable relative to the outer sleeve (24) to close or open the first e-liquid passage hole (2401). A buffer sealing structure is arranged between the connection sleeve (22) and the outer sleeve (24).

Abstract: A pixel circuit, including: an input sub-circuit, a driving control sub-circuit, a light emission control sub-circuit, a driving sub-circuit, a first light-emitting element and a second light-emitting element, wherein the driving control sub-circuit comprises a capacitor; the input sub-circuit is used for providing a signal of a data signal end to a first node; the driving control sub-circuit adjusts the voltages of the first node, a second node and a third node by means of controlling the voltages at two ends of the capacitor; the light emission control sub-circuit is used for providing a signal of a first power supply signal end to the second node under the signal control of a light emission control signal end; and the driving sub-circuit is used for connecting or disconnecting the connection between the second node and the third node under the signal control of the first node.

Abstract: Provided are certain triazolopyridines and triazolopyrazines of Formula 1, wherein X, Y, R1, R2, R3, R4 and R5 have any of the meanings described herein; processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of cell proliferative disorders.

Abstract: The present disclosure relates to methods for producing an antibody or an antigen-binding fragment thereof specifically binding to an antigen of interest, methods for inducing proliferation of PBMCs, B cell activation and differentiation, B cell maturation, and/or promoting class switch in an antibody-producing PBMC to produce IgG, compositions for the in vitro immunization and methods for identifying an antibody-enhancing factor for in vitro immunization.

Abstract: An adjustment structure and carburetor relating to the technical field of carburetors are provided. The adjustment structure includes: a throttle valve, a movable member and a movable member. The throttle valve is provided with an accommodating cavity and a sliding rail arranged in the accommodating cavity. The movable member is arranged in the accommodating cavity and slidably connected to the sliding rail. The rotating member is arranged in the accommodating cavity and threadedly engaged to the movable member, and rotates relative to the movable member and drives the movable member is configured to be driven to slide back and forth along the sliding rail through screws, so as to adjust a height of a jet needle connected with the movable member.

Abstract: The disclosure relates to a preparation and purification method for an antibody drug conjugate intermediate, and more particularly relates to a preparation and purification method for a linker part and drug part conjugate in an antibody drug conjugate, which can not only effectively remove impurities from a target product and by-products in a reaction process, making the purity of the target product finally obtained up to 99% or above, but also realize stable mass production and well meet the quality standard requirements of clinical drugs, so as to provide a tremendous guarantee for drug safety and stable supply.

Abstract: The present disclosure provides conjugates of polypeptides comprising nanobody and FGF21 linked by a polypeptide linker. The present disclosure further provides conjugates of polypeptides comprising GLP-1, nanobody, and FGF21 linked by two polypeptide linkers respectively. Pharmaceutical compositions comprising the same and methods of treating diseases are also provided.