Abstract: An ROR?t inhibitor, a preparation method thereof and uses thereof. The invention also relates to a pharmaceutical composition of the compound, a method for preparing the pharmaceutical composition, and use of the compound or the pharmaceutical composition in treating or preventing cancer, inflammation, or autoimmune diseases mediated by ROR?t in mammals.

Abstract: A negative electrode sheet, its fabricating method, and a battery containing negative electrode sheet are provided. The negative electrode sheet includes: a current collector; a first active layer provided on a surface of at least one side of the current collector, and a second active layer provided on a surface of one side of the first active layer away from the current collector, the first active layer is different from the second active layer, the first active layer includes a first active material including a first graphite, and the second active layer includes a second active material including a second graphite; and a ratio of the second capacity ratio for the second active material to the first capacity ratio for the first active material is greater than 1.

Abstract: The embodiments of the present disclosure provide a display panel, including: a base substrate, a first electrode layer, a luminescent material layer, a second electrode layer, an elastic lens layer and at least one light wavelength conversion layer arranged in sequence. The luminescent material layer is configured to emit an excitation light, the at least one light wavelength conversion layer is configured to convert the excitation light emitted from the luminescent material layer into light of a predetermined color, and the elastic lens layer is configured to converge the excitation light emitted from the luminescent material layer. The embodiments of the present disclosure further provide an electronic device and a method of manufacturing a display panel.

Abstract: A flapping-wing aerial robot formation control method includes: determining a trailing vortex generation mechanism, an energy saving principle and a trailing vortex attenuation mechanism of the formation flight of a group of wild geese in accordance with the pattern of the formation flight of the group of wild geese; determining the formation flight of a group of flapping-wing aerial robots and a formation switching solution in accordance with the trailing vortex generation mechanism, energy saving principle and trailing vortex attenuation mechanism of the formation flight of the group of wild geese in conjunction with the flapping characteristic of a flapping-wing aerial robot from the perspective of energy consumption equalization and energy saving; and carrying out formation keeping control and formation reconfiguration control in accordance with the formation flight of the group of flapping-wing aerial robots and the formation switching solution by controlling positions of the group of flapping-wing aeria

Abstract: A wedge to be used with a lockdown ring is disclosed. The lockdown ring is to be used with a wellhead. The wedge is enabled to engage a separation in the lockdown ring. The wedge includes a stopping feature to enable the wedge to be in one of a plurality of positions within the separation in the lockdown ring.

Abstract: A drive backboard, a manufacturing method thereof, a display panel and a display device are provided. The drive backboard includes a plurality of pixel units and a plurality of spare electrode groups. Each pixel unit includes m subpixel units, and m is a positive integer greater than or equal to 2. Each spare electrode group includes two first spare electrodes and one second spare electrode; two adjacent ith subpixel units respectively use one first spare electrode in each spare electrode group and share one second spare electrode in each spare electrode group, where i is a positive integer from 1 to m.

Abstract: A monoclonal antibody used for specifically binding to CAR molecules, which is characterized in that the monoclonal antibody comprises a light chain and a heavy chain, the light chain comprises CDR regions having an amino acid sequence as shown in SEQ ID NO: 1-3, and the heavy chain comprises CDR regions having an amino acid sequence as shown in SEQ ID NO: 5-7. By using the described monoclonal antibody or a CAR-T cell detection kit, the steps of CAR-T cell detection are simple, detection time is short, and the detection results are stable. An anti-FMC63 ScFv antibody can reduce the cost of detecting universal anti-CD19 CAR-T cells.

Abstract: Provided are a security apparatus, a manufacturing method thereof, and a battery. A first score-line and a second score-line are disposed on the security apparatus. The first score-line and the second score-line are connected to form a closed line. The first score-line and the second score-line divide the security apparatus into an outer frame and a valve sheet. A thickness of the security apparatus at the second score-line is greater than a thickness of the security apparatus at the first score-line. The valve sheet is capable of being separated from the outer frame along the first score-line and being kept in connection with the outer frame at the second score-line.

Abstract: A pull cord type turning mechanism for a butterfly-inspired flapping-wing aerial robot includes a motor, a cord reel, a cord reel gear, a potentiometer gear, a potentiometer, a control module, and a power supply. The control module is connected to the motor and the potentiometer. A rotary shaft of the motor is connected to the cord reel, the cord reel is coaxially connected to the cord reel gear, the cord reel gear is meshed with the potentiometer gear, and the potentiometer gear is connected to a rotary shaft of the potentiometer. The cord reel gear is provided with two cord grooves and two pull cords. One ends of the two pull cords are fixed in the two cord grooves, respectively, and the other ends thereof are fixed at the tips of front wings of two sides of the butterfly-inspired flapping-wing aerial robot, respectively.

Abstract: A method for preparing a polyol comprises the following steps of: (1) dissolving 2,3 -epoxybutane and an acid catalyst in an inert solvent to obtain a solution A; dissolving triethylene glycol in an inert solvent to obtain a solution B; and dissolving epoxy vegetable oil in an inert solvent to obtain a solution C; (2) respectively and simultaneously pumping the solutions A and B into a first micromixer for mixing; (3) pumping the solution C and an effluent of the first microreactor into a second micromixer for mixing while carrying out step (2); and (4) dissolving the vegetable oil polyol in an inert solvent to obtain a solution D; dissolving epoxypropane and an alkaline catalyst in an inert solvent to obtain a solution E; and pumping the solution D and the solution E into a tank reactor for reaction, thereby obtaining the polyol.

Abstract: The present disclosure relates to novel compounds, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions. In some embodiments, the compounds disclosed herein exhibit androgen receptor degradation activity.

Abstract: A method for extracting information, includes: obtaining an information stream comprising text and an image; generating, according to the text, embedded representations of textual entity mentions and a textual similarity matrix of the textual entity mentions and candidate textual entities; generating, according to the image, embedded representations of image entity mentions and an image similarity matrix of the image entity mentions and candidate image entities; and determining, based on an optimal transport, target textual entities of the textual entity mentions and target image entities of the image entity mentions according to the embedded representations of the textual entity mentions, the embedded representations of the image entity mentions, the textual similarity matrix and the image similarity matrix.

Abstract: A control system includes one or more levels of control of power and energy. At one level, a first controller optimally divides power between two or more processes, to maximize instantaneous production, for a given amount of currently available power. In the case of EDR desalination, electric power is optimally divided between ion exchange membranes and pumps to maximize instantaneous production of desalinated water for a given amount of available electric power. Optionally, at another level, a second controller divides time-varying power between the processes fed by the first level controller and an energy storage unit, based on a prediction of future power availability and a function. In the EDR case, power generated by a photovoltaic array is divided between the EDR desalination process and a battery, based on a prediction of future PV power availability and a function, to ensure reliable water production in the future.

Abstract: The present disclosure relates to novel compounds of Formula (I) that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: An integrated enhancement/depletion mode high electron mobility transistor (HEMT) includes a substrate, a buffer layer, a first barrier layer, a second barrier layer, a first source, a first drain a first gate, a second source, a second drain, and a second gate. The buffer layer is on the substrate. The first barrier layer is on the buffer layer, and the second barrier layer is on the first barrier layer. The second barrier layer covers a portion of the first barrier layer. The first source, the first drain, and the first gate are on the first barrier layer, and the second source, the second drain, and the second gate are on the second banner layer.

Abstract: A photomask, a method of manufacturing an array substrate, and a display panel are provided. The photomask includes a photomask line of a first conductive portion, a photomask line of a second conductive portion spaced apart from the photomask line of the first conductive portion, and a bridging line. Two opposite ends of the bridging line are respectively connected to the photomask line of the first conductive portion and the photomask line of the second conductive portion, and a width of the bridging line is less than a preset width.

Abstract: The present disclosure provides a negative electrode sheet, a preparation method thereof and a lithium ion battery containing the same. The negative electrode sheet includes a negative electrode current collector, where the negative electrode current collector includes a single-sided coating area and a double-sided coating area; in the double-sided coating area, second coating layers are disposed on both side surfaces of the negative electrode current collector, respectively, wherein each of the second coating layers includes a first negative electrode active material layer and a second negative electrode active material layer, the second negative electrode active material layer is disposed on a surface of the negative electrode current collector, and the first negative electrode active material layer is disposed on a surface of the second negative electrode active material layer.