Abstract: A massively multiplexed qPCR technique that allows genome-wide qPCR (100-100,000 targets simultaneously) with few-hour turnaround and at lost cost. A massively multiplexed isothermal amplification technique that allows genome-wide multiplexed isothermal amplification (100-100,000 targets simultaneously) with few-hour turnaround and at lost cost. Microwell array chips, isothermal amplification imaging devices and qPCR imaging devices for use with the techniques are provided also.

Abstract: Systems, methods and devices for profiling phenotypes of cells, and associated methods for identifying or predicting drug mechanism of action, discovering drug candidates with novel mechanisms of actions, differential subpopulation responses to drugs, and novel IR vibrational probes.

Abstract: A Raman spectroscopy-based platform for massively multiplexed detection of analytes of interest, such as nucleic acids or peptides, and a hardware platform for economical and high-throughput detection.

Abstract: Provided is a display panel, including: a base substrate, a display structure, a black matrix pattern, and a cylindrical lens structure layer. The black matrix pattern includes a plurality of first openings. The display panel is provided with a plurality of sub-pixel regions arranged in rows and columns. The first openings are disposed in the sub-pixel regions. The cylindrical lens structure layer includes a plurality of strip-shaped cylindrical lens structure and has a plurality of focal lines in an orthographic projection on the black matrix pattern. The focal lines are parallel to the length direction of the cylindrical lens structures. The focal lines partition each sub-pixel region into a plurality of regions. One of the plurality of regions is a non-crosstalk region. The black matrix pattern further includes second openings in the non-crosstalk regions. The second openings are disposed outside regions where the first openings are disposed.

Abstract: Provided is a display panel, including: a base substrate, a display structure, a black matrix pattern, and a cylindrical lens structure layer. The black matrix pattern includes a plurality of first openings. The display panel is provided with a plurality of sub-pixel regions arranged in rows and columns. The first openings are disposed in the sub-pixel regions. The cylindrical lens structure layer includes a plurality of strip-shaped cylindrical lens structure and has a plurality of focal lines in an orthographic projection on the black matrix pattern. The focal lines are parallel to the length direction of the cylindrical lens structures. The focal lines partition each sub-pixel region into a plurality of regions. One of the plurality of regions is a non-crosstalk region. The black matrix pattern further includes second openings in the non-crosstalk regions. The second openings are disposed outside regions where the first openings are disposed.

Abstract: A method for optical super-multiplexing using polyynes to provide enhanced images from stimulated Raman microscopy is disclosed. In some exemplary embodiments, the polyynes are organelle-targeted or spectral barcoded. Imaging can be enhanced by using the polyynes to image whole live cells or specific organelles within live cells. The polyynes can also be used in optical data storage (i.e., encoding) and identification (i.e., decoding) applications.

Abstract: Exemplary computer-accessible medium, systems, and methods are described herein which can provide an excited fluorescence radiation. In accordance with certain exemplary embodiments of the present disclosure, an excited fluorescence radiation can be provided using a beam of a probe so as to excite a molecule to an excited state for a fluorescence emission to effectuate the excited fluorescence radiation. The molecule can be detected based on the fluorescence emission. For example, the beam of the probe can be either the near-infrared spectrum or the visible light spectrum.

Abstract: A method for optical super-multiplexing using polyynes to provide enhanced images from stimulated Raman microscopy is disclosed. In some exemplary embodiments, the polyynes are organelle-targeted or spectral barcoded. Imaging can be enhanced by using the polyynes to image whole live cells or specific organelles within live cells. The polyynes can also be used in optical data storage (i.e., encoding) and identification (i.e., decoding) applications.

Abstract: Incorporation of deuterium into the lipids, proteins, and/or genetic material in cells, tissues, organs, or organisms, including animals, such as humans, and plants, by administration of heavy water, allows for the spectral determination of levels of lipids, proteins, and/or genetic material using Raman spectroscopy, such as stimulated Raman spectroscopy. Following administration of a drug, changes in the relative amounts of lipid, protein, and/or genetic materials can be determined, and the efficacy, or lack thereof, of the administered drug can be determined.

Abstract: Exemplary methods, systems and computer-accessible medium for detecting at least one condition of at least one disease. In particular, it is possible to administer at least one composition to at least one patient, where the at least one composition includes at least one bond-edited compound configured to target at least one of a disease tissue or a pathogen. Further, it is possible to receive information related to the administration of the composition to the patient. It is also possible to detect the at least one bond-edited compound using a Raman scattering arrangement.

Abstract: A tax category prediction model, which is trained using a tax category prediction dataset, provides a tax category prediction for an item having an item listing. The tax category prediction model enhances the ability and accuracy of identifying a tax category associated with an item for sale via the online marketplace (e.g., identifying the tax category before the item is offered for sale via the online marketplace). The tax category prediction dataset is generated based on one or more of a text embedding, an image embedding, another type of embedding, or a combination thereof. The text embedding may be identified by applying a natural language processing model to a text string of the item listing. The natural language processing model may comprise bidirectional encoder representations from transformers (BERT).

Abstract: An exemplar system, and computer-accessible medium for determining phenotypic (e.g., multi-parameter) information for a cell(s) can include, for example, generating spectral information of the cell(s) using a Raman spectroscopy procedure that is based on a vibrational probe(s), and determining the metabolic, protein biomarker, or signaling pathway information based on the spectral information. The Raman spectroscopy procedure can be a single-cell spontaneous Raman spectroscopy procedure. The single-cell Raman spectroscopy procedure can be performed using a whole-cell confocal micro-Raman spectrometer. The vibrational probe(s) can include a Deuterium-labeled branched-chain amino acid(s), or a deuterium-labeled palmitic acid(s), Raman active nanoparticles or other essential metabolites such as glucose and water.

Abstract: Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject, methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering.

Abstract: A delivery apparatus, a delivery system, a delivery method, an electronic device, and a computer readable storage medium are disclosed. The delivery apparatus includes a movable detachably and electrically connected with a cabin, where the movable chassis is configured to include: a first controller mounted inside the movable chassis, and a moving component mounted at a bottom of the movable chassis and connected with the first controller to drive the movable chassis and the cabin to move to a target position according to an instruction of the first controller; the cabin is configured to have one or more accommodation spaces for accommodating to-be-delivered objects. The technical solution greatly improves the delivery efficiency and reduces the delivery cost.

Abstract: An exemplary embodiment of the present disclosure provides a method, an apparatus, a system, an electronic device and a storage medium for robot navigation.

Abstract: Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject, methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering.

Abstract: Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject, methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering.

Abstract: Provided are an order delivery method, an electronic device, a delivery robot and a transfer system. The delivery robot includes a moving and storage system, an interaction apparatus and a control apparatus. The transfer system includes at least one storage bin, a transfer mechanism, an interaction apparatus and a control apparatus. The electronic device is configured to perform the order delivery method, including: obtaining an order set and status information of a delivery robot, and determining a delivery mode of the delivery robot for an in-delivery order according to the order set and the status information of the delivery robot. In these examples, the transfer or delivery of an order can be achieved by interaction of the delivery robot, the transfer system and the electronic device, thereby improving the efficiency of a delivery process.

Abstract: Exemplary computer-accessible medium, systems, and methods are described herein which can provide an excited fluorescence radiation. In accordance with certain exemplary embodiments of the present disclosure, an excited fluorescence radiation can be provided using a beam of a probe so as to excite a molecule to an excited state for a fluorescence emission to effectuate the excited fluorescence radiation. The molecule can be detected based on the fluorescence emission. For example, the beam of the probe can be either the near-infrared spectrum or the visible light spectrum.

Abstract: An elevator scheduling method and an apparatus, a server, and a computer-readable storage medium are provided. The elevator scheduling method is applied to a server, and comprises: determining an elevator schedule request, wherein the elevator schedule request comprises starting floor information and target floor information; determining a target elevator to be scheduled to a target robot based on the elevator schedule request and operation information of schedulable elevators; generating a control instruction based on the starting floor information, the target floor information, and identification information of the target elevator; and sending the control instruction to an elevator control device, wherein the elevator control device controls movement of the target elevator.