Abstract: A multiplexing scheme for both energy and timing information is provided for a particle detection system having an optical sensor array with multiple optical sensors. Each optical sensor is associated with multiple scintillator modules. The system has a segmented prismatoid light guide comprising multiple prismatoid segments. Each segment is associated with multiple optical sensors, where the optical sensors are adjacent. One end each scintillator module is in contact with its associated optical sensor and the other is in contact with its associated segment. Multiple optical sensors may be connected to an energy readout channel, respectively, such that optical sensors associated with the same segments are not connected to the same energy readout channel. Each energy readout channel has at least two timestamps associated therewith.

Abstract: Disclosed are antigen binding constructs targeting HER2 and uses thereof. Specifically provided is an antibody comprising a monovalent antigen-binding fragment that specifically binds to the HER2 ECD4 antigen on HER2-expressing cells, with the heavy chain variable region containing a mutation at position 30 and the light chain variable region containing a mutation at position 53, both according to Kabat numbering, a nucleic acid that encodes the same, a vector that comprises said nucleic acid, a cell that comprises an isolated nucleic acid of said vector, and a pharmaceutical composition that comprises the foregoing. Further provided are uses thereof in aspects such as treating subjects who suffer from HER2-expressing tumors, killing HER2-expressing tumor cells, or inhibiting the growth of HER2-expressing tumor cells.

Abstract: Disclosed are a high-strength aluminum alloy powder and preparation method thereof, as well as high-strength aluminum alloy parts and additive manufacturing method thereof. The high-strength aluminum alloy powder includes the following components by weight percentage: 4.0 wt. % to 7.0 wt. % of Zn, 1.5 wt. % to 3.5 wt. % of Mg, 1.0 wt. % to 3.5 wt. % of Cu, the content of Sc is a, and 0.4 wt. %?a?1.3 wt. %, at most 0.2 wt. % of Zr, at most 0.5 wt. % of Fe, at most 0.4 wt. % of Si, at most 0.5 wt. % of Mn, at most 0.2 wt. % of Ti, at most 0.28 wt. % of Cr, at most 0.05 wt. % of O and N, and the balance of Al.

Abstract: The present invention relates to a class of 4-methanesulfonylbenzamide compounds with sulfur-containing substituents at the 3-position, represented by general formula (I), including their stereoisomers, agriculturally acceptable salts, preparation methods, herbicidal compositions, and their use in the field of plant protection, wherein R1, R2, X, Q, and n are as defined herein.

Abstract: A liquid crystal display panel is provided. The liquid crystal display panel includes: a first substrate and a second substrate arranged opposite to each other, and a liquid crystal layer and a plurality of strip-shaped spacers disposed between the first substrate and the second substrate. In the liquid crystal display panel, there is an overlapping area between an orthographic projection of a first signal line on a target base and an orthographic projection of a second signal line on the target base, and an orthographic projection of the strip-shaped spacer on the target base is not overlapped with the overlapping area.

Abstract: A switched capacitor voltage converter includes an inductor and a plurality of switch transistors between two branches of a conventional parallel switched capacitor voltage converter, by controlling a turning on and off of the plurality of switch transistors, electric charges on a parasitic capacitor of a first branch are completely transferred to a second branch via the inductor within a period of time when all primary switch transistors are turned off, so that a voltage difference between both terminals of each of the primary switch transistors becomes zero, then the each of the primary switch transistors is turned on, the voltage difference between both terminals of the each of the primary switch transistors becomes zero at an instant when the each of primary switch transistors is turned on respectively, therefore a switching loss of the plurality of switch transistors is reduced and a conversion efficiency is improved.

Abstract: The present application provides a silicon-based negative electrode material and a preparation method and use thereof. The silicon-based negative electrode material has a lithium borate coating layer on its surface, which may improve first charge-discharge efficiency of the material. There is a strong chemical bond interaction between the lithium borate coating layer and the borate ester having a specific structure, which may improve the rate capability of the battery. Furthermore, the borate ester has a structure of —(CH2CH2O)n—CO—CR0?CH2, and the negative plate prepared with the silicon-based negative electrode material will undergo a cross-linking reaction during a high-temperature baking of the plate, so that a cross-linking is formed among particles of the silicon-based negative electrode material, thereby effectively ensuring the structural integrity of the silicon-based negative electrode plate during recycling, and improving the cycle performance of the battery.

Abstract: The embodiments of the present disclosure provide a display substrate, a display panel, and a display device. The display substrate includes: a first base substrate, wherein a plurality of sub-pixel regions arranged in an array are provided on the first base substrate; and a reflective layer provided on one side of the first base substrate, wherein a surface of the reflective layer away from the first base substrate is formed to include a plurality of first bumps and a plurality of second bumps, and the first bump has a size greater than that of the second bump.

Abstract: Disclosed is an electronic control system connected to a gas judgment assembly with an oxygen depletion sensor assembly and a sensor such as an ion induction needle to determine whether a flame is present. The gas judgment assembly includes a nozzle associated with the oxygen depletion sensor assembly that is large enough to permit a flame if the fuel is liquid propane, but small enough to prevent a flame if the fuel is natural gas, and send a signal indicating a flame or no flame status to the control system. The control system can thereafter determine whether a flame is present and, if so, conclude that liquid propane fuel is being directed to the gas judgment assembly while the system is in the natural gas mode. The control system can then open a relay, disconnecting current flow to a solenoid valve if a flame is sensed.

Abstract: Disclosed is a bogie framework of a rail vehicle and a bogie, wherein the bogie framework of the rail vehicle includes a first end beam (01), a second end beam (02) and a box beam disposed between the first end beam (01) and the second end beam (02). The box beam includes a primary gearbox (1) and a secondary gearbox (2), and the primary gearbox (1) is used for connecting a traction motor and the secondary gearbox (2). The secondary gearbox (2) is disposed between the primary gearbox (1) and the first end beam (01), as well as between the primary gearbox (1) and the second end beam (02).

Abstract: A polycarbonate composition comprises: a copolycarbonate comprising repeating units derived from a cyclohexylidene-bridged bisphenol; and an auxiliary polycarbonate comprising a branched homopolycarbonate; a poly(1,4-cyclohexanedimethylene terephthalate), a copolycarbonate derived from an isophorylidene-bridged bisphenol, and optionally a poly(alkylene cyclohexanedicarboxylate), poly(carbonate siloxane) having a siloxane content of less than 20 wt % based on the total weight of the poly(carbonatesiloxane), poly(aliphatic ester-carbonate) comprising bisphenol A carbonate units and C6-12 dicarboxy ester units; or a combination thereof. The polycarbonate compositions have one or more of a transparency of 89% or greater on 2.5 mm plaques according to ASTM-D1003-00; and a heat deformation temperature of at least 111° C., or at least 127° C. at 0.45 MPa or at least 98° C., or at least 110° C. at 1.82 MPa as determined on 3.18 mm bars per ASTM D648.

Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S or G12C. The compounds have a general Formula I: (I) wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.

Abstract: A hole finishing tool includes a shank, a body, and a plurality of cutting inserts. The body extends axially from the shank. The body includes ribs. Each of the ribs include a respective pocket. Each cutting insert is attached to the respective pocket of the respective rib. Each cutting insert includes a cutting edge and a chip breaker pocket. The chip breaker pocket is disposed in a rake face of the cutting insert. The chip breaker pocket includes a front boundary and a chip wall. The front boundary is parallel to the cutting edge. The chip wall is disposed at a rotation angle relative to the cutting edge. The rotation angle ranges between 0° to 50°.

Abstract: Disclosed are a LiDAR assembly and an apparatus with a detection function. The LiDAR assembly includes: a transmitter configured to emit first laser light along a first direction; a first scanner, where an input terminal of the first scanner faces to an output terminal of the transmitter, and the first scanner is configured to control the first laser light to be deflected from the first direction to a plurality of different first deflection directions, and emit the first laser light along the plurality of first deflection directions to a target object; a receiver configured to receive laser light reflected by the target object and convert an optical signal into an electrical signal; and a signal processing unit configured to receive the electrical signal, analyze and compute the electrical signal to obtain information about a distance from the target object and a shape of the target object.

Abstract: A dual-frequency antenna and an electronic device are provided, and belong to the field of communication technology. The dual-frequency antenna includes a first antenna unit and a second antenna unit opposite to each other, and a filtering unit therebetween. An operating frequency band of the first antenna unit is a first frequency band; an operating frequency band of the second antenna unit is a second frequency band; the filtering unit is configured to reflect an electromagnetic wave of the first frequency band and to transmit an electromagnetic wave of the second frequency band; the first antenna unit is configured to receive the electromagnetic wave of the first frequency band and to reflect the received electromagnetic wave of the first frequency band by the filtering unit; and the second antenna unit is configured to receive and reflect the electromagnetic wave of the second frequency band transmitted by the filtering unit.

Abstract: A fuel injection assembly for a combustor of a gas turbine engine includes a body with a head section that defines an air intake chamber. A mixing chamber is disposed below the air intake chamber. A deflection member is disposed in the air intake chamber and includes an upper deflection surface and sides spaced apart from inner wall surfaces of the air intake chamber such that peripheral air passages are defined for air to pass from the air intake chamber into the mixing chamber. A plurality of radially extending and longitudinally spaced-apart ribs is disposed along longitudinal side walls of the mixing chamber. A fuel plenum is disposed along the longitudinal side walls of the mixing chamber, and a plurality of fuel injection holes is defined from the fuel plenum through the longitudinal side walls of the mixing chamber and at least some of the ribs.

Abstract: A series-parallel switched capacitor voltage converter includes inductive branch, a first branch and a second branch, the inductive branch is connected between the first branch and the second branch. By controlling turning on and off of the switches of the first branch, the second branch and inductive branch, charges on capacitors of one branch are completely transferred to another branch via the inductive branch within a period of time after all main switches of the first branch and the second branch are turned off, and a voltage difference between both terminals of each of the main switches becomes zero, then each of the main switches is started to be turned on, the voltage difference of each of the main switches is zero at an instant when the main switches are turned on.

Abstract: The present disclosure provides compounds useful for the inhibition of KRAS. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.

Abstract: Provided are a device for detecting sub-atomic particles and method of fabrication thereof. The device includes a plurality of scintillators, a detector provided on a first end of the plurality of scintillators and a prismatoid provided on a second end of the plurality of scintillators. The prismatoid redirects light between adjacent scintillators of the plurality of scintillators.

Abstract: A method for preparing a sustained-release antibacterial film includes: (1) mixing a cyclodextrin metal-organic framework (CD-MOF) material with a silver nitrate short-chain alcohol solution to prepare an intermediate material A; (2) mixing the intermediate material A with a caffeic acid short-chain alcohol solution to prepare an intermediate material B; (3) dispersing the intermediate material B in a solvent, adding a polydimethylsiloxane main agent and a PDMS auxiliary agent in sequence, and mixing well by stirring to obtain a casting solution; and (4) coating the casting solution on a film support material, conducting vacuum drying, and peeling off a film from the film support material to obtain the sustained-release antibacterial film. A mixed matrix-based film material in which the CD-MOF and the PDMS are physically blended is prepared based on CD-MOF and PDMS for the first time, and may be used in application researches of food, environment and other fields.