Abstract: A sulfoximine-containing ATR inhibitor compound as represented by formula (I), a preparation method therefor, a pharmaceutical composition containing same, and the use thereof in the treatment of ATR-related or ATR-mediated diseases and/or conditions.

Abstract: The present disclosure provides a group training action correction system and method combining face and gesture recognition, wherein the system includes an individual action correction moment determination module, which is configured to determine a nearest individual action correction moment after a current training progress on a preset training progress axis; and an individual action correction module, which is configured to correct and prompt individually action for the action correction object based on a standard gesture, an action to be corrected, and a personnel identity when entering the individual correction moment.

Abstract: An electronic device may have a hinge that allows the device to be flexed about a bend axis. A display may span the bend axis. The device may have a stainless steel and/or carbon fiber reinforced polymer layer with slots. The slots may overlap the bend axis. The slots may have at least one property that varies in a non-linear manner as a function of position on the layer. The device may include an adhesive layer with a cutout that overlaps the slots. An interface that defines the cutout may have a plurality of recesses with varying depths. A flexible printed circuit may be attached to an edge of the display panel. The display cover layer may overlap a bonding region between the flexible printed circuit and the edge of the display panel. A UV-curable gap filler may be interposed between the flexible printed circuit and the display cover layer.

Abstract: An electronic device may have a hinge that allows the device to be flexed about a bend axis. A display may span the bend axis. The device may have a stainless steel and/or carbon fiber reinforced polymer layer with slots. The slots may overlap the bend axis. The slots may have at least one property that varies in a non-linear manner as a function of position on the layer. The device may include an adhesive layer with a cutout that overlaps the slots. An interface that defines the cutout may have a plurality of recesses with varying depths. A flexible printed circuit may be attached to an edge of the display panel. The display cover layer may overlap a bonding region between the flexible printed circuit and the edge of the display panel. A UV-curable gap filler may be interposed between the flexible printed circuit and the display cover layer.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive, from a high speed train (HST) cell, a system information block (SIB) indicating an HST flag based at least in part on the UE camping on the HST cell. The UE may disconnect from the HST cell and camping on a non-HST cell based at least in part on a UE mobility in an HST railway. The UE may determine that disconnecting from the non-HST cell and camping on a new HST cell is to be prioritized over remaining on the non-HST cell, based at least in part on the UE being in the HST railway and based at least in part on a priority of HST cells being greater than a priority of non-HST cells. Numerous other aspects are described.

Abstract: A method for generating a pre-trained language model, includes: obtaining sample files; obtaining typography structure information and text information of the sample files by parsing the sample files; obtaining a plurality of task models of a pre-trained language model; obtaining a trained pre-trained language model by jointly training the pre-trained language model and the plurality of task models according to the typography structure information and the text information; and generating a target pre-trained language model by fine-tuning the trained pre-trained language model according to the typography structure information and the text information.

Abstract: Apparatus and methods of Hybrid Automatic Repeat Request (HARQ) Acknowledgement (ACK) feedback for multiple Physical Downlink Control Channel (PDCCH) based multiple Transmit Receive Points (TRP) transmission are disclosed. The apparatus includes: a receiver that receives a plurality of configurations of control resource sets (CORESETs), wherein each CORESET comprises a plurality of resource blocks (RBs) in frequency domain and a plurality of symbols in time domain, and time-frequency resources identified by the CORESET are used to transmit a Downlink Control Information (DCI); a processor that determines a Hybrid Automatic Repeat Request (HARQ) Acknowledgement (ACK) feedback selected from a group consisting of: a separate HARQ-ACK feedback and a joint HARQ-ACK feedback; and a transmitter that transmits the determined HARQ-ACK feedback; wherein the separate HARQ-ACK feedback is transmitted through a plurality of uplink resources; and the joint HARQ-ACK feedback is transmitted through one uplink resource.

Abstract: An all-in-one wafer cleaning machine for monocrystalline silicon production includes: a circulation track disposed at a rear end of a cleaning equipment main body and fixed to the cleaning equipment main body; a horizontal moving device disposed at an outer side of the circulation track; a first motor fixedly installed at one end inside the horizontal moving device; a first transmission gear disposed at an output end of the first motor; a first fixed rod fixedly disposed at the other end of the horizontal moving device; a first fixed gear disposed at one end of the first fixed rod, wherein the first transmission gear and the first fixed gear are engaged with the circulating track; and a vertical track fixedly disposed at the horizontal moving device.

Abstract: The present disclosure belongs to the technical fields of computational medicine and clinical oncology, and specifically relates to a molecular subtyping method for gastric cancer (GC) based on metabolic genes, a construction method for a prognostic prediction model and applications. In the present disclosure, metabolic process alterations are overall assessed, and new metabolic transcription patterns based on 456 metabolic gene-related signatures are identified. Three different metabolic patterns are validated by unsupervised consensus clustering analysis and independent datasets, and molecular and clinical pathological features of these three metabolite clusters have different metabolic gene expressions, pathway enrichments, gene variations, and survival outcomes.

Abstract: Disclosed in the present invention are an Apple Watch-based HTML5 somatosensory game method and device, and a computer-readable storage medium. The method comprises: when a somatosensory game program is started, caching a game resource package from a server to a local device; after a somatosensory game is started, obtaining somatosensory data from a bound Apple Watch; generating a corresponding game instruction according to the somatosensory data; sending the game instruction to the somatosensory game program on the local device in real time; and synchronizing a game state of the somatosensory game to the server based on a preset synchronization mechanism. The Apple Watch-based HTML5 somatosensory game method of the present invention can provide better performance, lower delay, offline support and higher data security while reducing the dependence on the network and providing better player experience.

Abstract: The present disclosure provides an array substrate including a plurality of pixel units, at least one of the pixel units includes a first pixel sub-unit, the first pixel sub-unit includes a first transistor, a second transistor, and a first pixel electrode; the first transistor includes a first active pattern, the second transistor including a second active pattern, the first active pattern includes a first channel region, the second active pattern includes a second channel region; at least one division pattern is arranged between a third electrode and a fourth electrode, and an orthographic projection of the division pattern on a first base substrate is partially overlapped with an orthographic projection of the second channel region on the first base substrate.

Abstract: T cell receptors that specifically recognize hAFP158 and methods of their use are provided.

Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.

Abstract: A pyrazole derivative, and a preparation method therefor and a use thereof in medicine are described. In particular, provided are a PRMT5 inhibitor having a structure shown in formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use thereof as a PRMT5 inhibitor, and a use thereof in treatment and/or prevention of a PRMT5-mediated disease.

Abstract: The present disclosure relates to systems, software, and computer-implemented methods for automatically identifying handwritten tips. An example method includes obtaining an image of a receipt, where the image includes a reference region in a pre-set format, a plurality of category identifiers, and at least one set of handwritten characters. The reference region and the plurality of category identifiers can be printed. The plurality of category identifiers can be located at pre-set positions relative to the reference region. The method further includes obtaining optical character recognition (OCR) information of the image and identifying the reference region from the OCR information based on the pre-set format of the reference region. The method further includes determining a plurality of amounts based on the OCR information and the reference region, where at least one of the plurality of amounts is associated with a tip category.

Abstract: A temperature compensation bias circuit is provided, including a third resistor, a fourth resistor, a fifth resistor, a sixth resistor, a seventh resistor, a second capacitor, a third capacitor, a fifth capacitor, a fifth transistor, a sixth transistor, and a seventh transistor. A power amplifier is further provided, the power amplifier applies the temperate compensation bias circuit. Compared with the prior art, there are fewer effects on a bias point of the temperature compensation bias circuit when the temperature compensation bias circuit and the power amplifier are in RF operating states, the power amplifier is enabled to have good temperature compensation effect and high linearity.

Abstract: The present invention relates to compounds of formula (I), wherein R1 to R6, m and n are I a described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Abstract: A composite plate includes a first plate (5); a second plate (16); and a first side surface of the first plate (5) including striations. A first side surface of the second plate (16) and the first side surface of the first plate (5) are rolled to connect, and wherein adjacent striations (14) have a pitch of 0.005 mm to 0.03 mm account for more than 90% of all the striations (14).

Abstract: The present invention relates to compounds of formula (I), wherein R1 to R3, A, M, W and Q are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.