Abstract: An electrical arrangement (1), comprising a housing (2) having a housing opening (20), an electrical component (3) within the housing (20), a power supply connection (4), a contact protection cover (5), and a circuit breaker (6) which can be inserted into the housing (2), wherein, in the inserted state, the circuit breaker (6) connects the electrical component (3) to the power supply connection (4) and, in the withdrawn state, the circuit breaker (6) disconnects the connection, wherein the contact protection cover (5) can be fastened to the housing (2) in a locking position in which the contact protection cover (5) covers the housing opening (20), and wherein, in the inserted state, the circuit breaker (6) locks the contact protection cover (5) in the locking position.

Abstract: The present invention relates to the technical field of material processing and provides a method for making a metal material composite, including: contacting a first surface of a first plate with a second surface of a second plate; placing the first plate and the second plate in a recess in a circumferential direction of a first roller such that a third surface of the second plate contacts a bottom wall of the recess in a circumferential, the third surface being opposite the second surface, the first plate having a greater hardness than the second plate; and controlling a first roller and a second roller to rotate, thereby rolling to combine the first plate and the second plate into a composite plate, where a fourth surface of the first plate contacts a surface of the second roller and the fourth surface is opposite the first surface during the rolling.

Abstract: The present invention provides a composite plate, a composite plate roughening device, and a method for manufacturing a composite plate, and relates to the technical field of metal plate materials. The composite plate includes a first plate and a second plate, wherein a first side surface of the first plate is provided with striations, the first side surface of the second plate and the first side surface of the first plate are rolled to connect, and the striations of which adjacent ones have a pitch of 0.005 mm to 0.03 mm account for more than 90% of all the striations.

Abstract: The present invention provides a cell phone frame and a method for manufacturing the same, and relates to the technical field of cell phone accessories. The cell phone frame includes a composite plate, the composite plate encloses a accommodation space for accommodating the cell phone, the composite plate includes a first plate and a second plate, a first side surface of the first plate is provided with striations, the first side surface of the second plate and the first side surface of the first plate are rolled to connect, and the striations of which adjacent ones have a pitch of 0.005 mm to 0.03 mm account for more than 90% of all the striations.

Abstract: Provided are compounds reducing SAICAR accumulation, and applications. On the basis of existing protein structure data and small molecule structure data, calculations and analysis are performed using software to screen and obtain compounds capable of effectively interfering with PAICS activity, reducing SAICAR synthesis, and ultimately reducing SAICAR accumulation, in order to achieve the goal of treating or improving ADSL deficiency. A better effect in the treatment or improvement of ADSL deficiency is expected from the joint use of at least two of the described compounds.

Abstract: The present invention relates to compounds of formula (I), (I), wherein R1, R2, R3, R4 and A are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.

Abstract: The present invention discloses application of compounds in the preparation of reagents for down-regulation of Runx2. The inventors have confirmed through computational studies and disease models that Fostamatinib, Regorafenib and melatonin can significantly down-regulate the expression of Runx2, and have a significant targeted therapeutic effect on cancers with abnormally high expression of Runx2, and are efficient reagents for reducing the expression of Runx2. Especially the Runx2 expression down-regulation reagent used in the laboratory.

Abstract: The disclosure discloses a method for manufacturing a solar cell, a solar module, and a power generation system. The manufacturing method includes the following steps: S1: perforating film layer in a first region and/or a second region of a solar cell where an electrode is to be disposed, thus forming a plurality holes; S2: growing a plurality seed layers on the solar cell, contacting with the first region and/or the second region through the plurality of holes or grooves in S1; and S3: horizontally transporting a to-be-electroplated solar cell on a horizontal electroplating device, to form a cathode on the seed layer, where an anode terminal is disposed in an electroplating liquid in an electroplating bath, and a moving mechanism disposed in the electroplating bath drives the solar cell to move from inlet to outlet, thus achieving electroplating.

Abstract: The present invention relates to compounds of formula (I), wherein R1, R2, R3, R4, R5 and A are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.

Abstract: A system associated with predicting segmentation quality of segmented objects implemented in the analysis of copious image data is disclosed. The system receives a collection of image data related to a particular type of data. The image data is segmented into segmented data portions based on an object associated with the collection of image data. Regions of interest associated with the segmented data portions are determined. The quality of segmentation of the segmented data portions is determined for respective classification of the regions of interest. A classification label is assigned to the regions of interest. Regions of interest are partitioned into sub-regions. Features associated with the sub-regions of the segmented data portions are determined. A training dataset is generated based on the determined features associated with the sub-regions in order to train a classification model based on a predetermined threshold value.

Abstract: The present invention discloses an anti-interference structure of a millimeter wave antenna, comprising an emitting array antenna and/or receiving array antenna including at least one comb-shaped antenna assembly. The comb-shaped antenna assembly is provided with a long-strip-shaped antenna body and a micro-strip antenna radiation assembly; one end of the antenna body is connected with a millimeter wave circuit capable of generating millimeter waves; the micro-strip antenna radiation assembly includes a plurality of middle micro-strip antenna radiation units which are arranged on the middle section of the antenna body at intervals, and a tail-end micro-strip antenna radiation unit which is arranged at the tail end of the antenna body; and the each middle micro-strip antenna radiation unit and the tail-end antenna radiation unit are arranged on the antenna body at intervals in the same skew direction, such that the interference phenomenon of the opposite-direction noises is reduced.

Abstract: Provided are an item ex-warehouse method and apparatus, a device, and a storage medium. The method includes that: virtual warehouse location in-warehouse information is received based on a cancel instruction of a first item acquisition task and based on a determination result that a package is in an undelivered state; an item being ex-warehoused is determined based on a generation instruction of a second item acquisition task and based on a determination result that it is determined that the second item acquisition task includes the item and a route includes an express delivery station; and the item and virtual warehouse location ex-warehouse information are associated with the second item acquisition task.

Abstract: Provided are an intermediate for synthesizing a camptothecin derivative, a preparation method therefor, and the use thereof. An intermediate A can be obtained from 3-fluoro-4-methylaniline by means of acylation, bromination, and cross-coupling reactions. The intermediate A can be used for preparing an intermediate B to further prepare exatecan mesylate. The intermediate compound B can be obtained from the intermediate A by means of a rearrangement reaction, and exatecan mesylate can be obtained from the intermediate compound B by means of deprotection for acetamido and amino at the a site, a condensation reaction, and a hydrolysis reaction. The reaction starting materials have a low price, the reaction conditions of each step are moderate, the operation is simple, and the yield is high, such that the intermediate is suitable for industrial production.

Abstract: The present disclosure relates to benzimidazole derivatives, a preparation method therefor and a medical use thereof. Specifically, the present disclosure relates to a benzimidazole derivative represented by the general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and its use as a therapeutic agent, in particular its use for the treatment of diseases related to P2X3 activity.

Abstract: Provided are a chimeric antigen receptor targeting CD20 antigen and a preparation method thereof. The extracellular antigen binding domain of the chimeric antigen receptor includes an antibody heavy chain variable region shown in SEQ ID NO: 7 or 9 or 33 and an antibody light chain variable region shown in SEQ ID NO: 11 or 13 or 35, and is capable of killing tumor cells.

Abstract: The present invention relates to compounds of formula (I), ab (I), wherein R1 to R3 and L are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Abstract: It is provided a method performed by a beamformer device for channel sounding in a network including a beamformer device and at least one beamformee device. In each round of channel sounding, the beamformer device may send an announcement message including identification information of beamformee devices included in a list when the list is not empty and clearing the list, wherein the beamformee devices included in the list have moved a distance exceeding a threshold value.

Abstract: The present invention relates to an R-T-B sintered magnet and a preparation method thereof. The sintered magnet includes a grain boundary region T1, a shell layer region T2 and an R2Fe14B grain region T3; at 10 ?m to 60 ?m from a surface of the sintered magnet toward a center thereof, an area ratio of the shell layer region T2 to the R2Fe14B grain region T3 is 0.1 to 0.3, and a thickness of the shell layer region T2 is 0.5 ?m to 1.2 ?m; and an average coating percent of the shell layer region T2 on the R2Fe14B grain region T3 is 80% or more. In the present invention, by optimizing a preparation process and a microstructure of a traditional rare earth permanent magnet, diffusion efficiency of heavy rare earth in the magnet is improved, such that coercivity of the magnet is greatly improved, and manufacturing cost is reduced.

Abstract: The present invention relates to compounds of formula (I), wherein R1 to R3 and n are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.

Abstract: Applications of spermine or its pharmaceutically acceptable derivative in preparation of an SAICAR synthetase activity interfering agent or inhibitor. Applications of spermine or its pharmaceutically acceptable derivative in preparation of antitumor drug.