Patents by Inventor Weilan Ye

Weilan Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-LRP5 ANTIBODIES AND METHODS OF USE
    Publication number: 20190010228
    Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
    Type: Application
    Filed: June 26, 2018
    Publication date: January 10, 2019
    Applicant: Genentech, Inc.
    Inventors: Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu
  • Method of treating retinopathy with an anti-LRP5 antibody
    Patent number: 10035854
    Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: July 31, 2018
    Assignee: GENENTECH, INC.
    Inventors: Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu
  • ANTI-LRP5 ANTIBODIES AND METHODS OF USE
    Publication number: 20170166636
    Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
    Type: Application
    Filed: November 11, 2016
    Publication date: June 15, 2017
    Applicant: Genentech, Inc.
    Inventors: Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu
  • Methods for inhibiting angiogenesis using EGFL8 antagonists
    Patent number: 9549971
    Abstract: The present invention provides methods of using EGFL8 antagonists to inhibit vascular development and to treat related disorders.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: January 24, 2017
    Assignee: GENENTECH, INC.
    Inventors: Weilan Ye, Han Lu
  • Anti-LRP5 antibodies and methods of use
    Patent number: 9522954
    Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: December 20, 2016
    Assignee: GENENTECH, INC.
    Inventors: Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu
  • ANTI-LRP5 ANTIBODIES AND METHODS OF USE
    Publication number: 20160185855
    Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
    Type: Application
    Filed: October 9, 2015
    Publication date: June 30, 2016
    Applicant: GENENTECH INC.
    Inventors: Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu
  • Antibodies
    Patent number: 9284376
    Abstract: The present invention relates to the use of VEGF antagonists and a novel anti-?5?1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-?5?1 antibodies and methods of making and using them.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: March 15, 2016
    Assignee: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
  • TREATMENT OF DISORDERS WITH ALTERED VASCULAR BARRIER FUNCTION
    Publication number: 20150366930
    Abstract: The present invention provides methods of using RASIP1 agonists and antagonists to modulate vascular barrier function and regulate new vessel formation, and to treat related disorders.
    Type: Application
    Filed: January 23, 2015
    Publication date: December 24, 2015
    Inventors: Weilan YE, Leon H. PARKER, Christopher W. WILSON
  • Anti-LRP5 antibodies and methods of use
    Patent number: 9200072
    Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: December 1, 2015
    Assignee: GENENTECH INC.
    Inventors: Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu
  • NOVEL ANTI- ALPHA5 BETA1 ANTIBODIES AND USES THEREOF
    Publication number: 20150203581
    Abstract: The present invention provides new anti-?5?1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 23, 2015
    Inventors: Wei-Ching LIANG, Gregory D. PLOWMAN, Yan WU, Weilan YE
  • METHODS FOR INHIBITING OCULAR ANGIOGENESIS
    Publication number: 20150093375
    Abstract: The present invention provides methods of using TSPAN12 and Norrin antagonists to inhibit ocular vascular development and to treat related disorders.
    Type: Application
    Filed: April 25, 2014
    Publication date: April 2, 2015
    Applicant: GENENTECH, INC.
    Inventors: Harald J. JUNGE, Weilan YE
  • Anti-?5?1 antibodies and uses thereof
    Patent number: 8962275
    Abstract: The present invention provides new anti-?5?1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: February 24, 2015
    Assignee: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
  • Antibodies
    Patent number: 8840887
    Abstract: The present invention relates to the use of VEGF antagonists and a novel anti-?5?1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-?5?1 antibodies and methods of making and using them.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: September 23, 2014
    Assignee: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
  • Compositions and methods for modulating vascular development
    Patent number: 8790646
    Abstract: The present invention provides methods of using EGFL7 antagonist to modulate vascular development. Also provided herein are methods of screening for modulators of EGFL7 activity. Furthermore, methods of treatment using EGFL7 antagonists are provided.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: July 29, 2014
    Assignee: Genentech Inc.
    Inventors: Ellen Filvaroff, Weilan Ye, Leon H. Parker, IV, Jo-Anne S. Hongo, Maike Schmidt
  • TREATMENT OF DISORDERS WITH ALTERED VASCULAR BARRIER FUNCTION
    Publication number: 20140005113
    Abstract: The present invention provides methods of using RASIP1 agonists and antagonists to modulate vascular barrier function and regulate new vessel formation, and to treat related disorders.
    Type: Application
    Filed: September 10, 2013
    Publication date: January 2, 2014
    Applicant: Genentech, Inc.
    Inventors: Weilan Ye, Leon H. Parker, IV, Christopher W. Wilson
  • COMBINATORIAL THERAPY
    Publication number: 20140004038
    Abstract: The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.
    Type: Application
    Filed: December 7, 2012
    Publication date: January 2, 2014
    Applicant: Genentech, Inc.
    Inventors: Anan Chuntharapai, Gregory D. Plowman, Marc Tessier-Lavigne, Yan Wu, Weilan Ye
  • HUMANIZED ANTI-EGFL7 ANTIBODIES AND METHODS USING SAME
    Publication number: 20130324704
    Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
    Type: Application
    Filed: July 17, 2013
    Publication date: December 5, 2013
    Inventors: Weilan YE, Mark S. Dennis, Jill Fredrickson
  • Humanized anti-EGFL7 antibodies and methods using same
    Patent number: 8574576
    Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: November 5, 2013
    Assignee: Genentech, Inc.
    Inventors: Weilan Ye, Mark S. Dennis, Jill Fredrickson
  • HUMANIZED ANTI-EGFL7 ANTIBODIES AND METHODS USING SAME
    Publication number: 20130287779
    Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
    Type: Application
    Filed: June 17, 2013
    Publication date: October 31, 2013
    Inventors: Weilan YE, Mark S. Dennis, Jill Fredrickson
  • NOVEL ANTI- ALPHA5BETA1 ANTIBODIES AND USES THEREOF
    Publication number: 20130095096
    Abstract: The present invention provides new anti-?5?1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
    Type: Application
    Filed: December 22, 2011
    Publication date: April 18, 2013
    Applicant: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye