Patents by Inventor Weilan Ye

Weilan Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel secreted polypeptide and methods of treatment of bone disorders
    Publication number: 20030044897
    Abstract: The present invention is directed to a novel polypeptide and to nucleic acid molecules encoding that polypeptide. Also provided herein are methods of treating and diagnosing bone disorders.
    Type: Application
    Filed: December 13, 2001
    Publication date: March 6, 2003
    Applicant: GENENTECH, INC.
    Inventors: Audrey Goddard, William I. Wood, Weilan Ye, Zemin Zhang
  • Method of dopaminergic and serotonergic neuron formation from neuroprogenitor cells
    Patent number: 6277820
    Abstract: The present invention relates to neuronal formation and methods of treating diseases characterized by abnormalities in the activity of dopaminergic (DA) and serotonergic (5HT) neurons. In particular, the invention relates to a method of forming serotonergic neurons in vitro by contacting neuroprogenitor cells to an effective amount of native sequence, variants and functional fragments of FGF-4, FGF-8 and Shh. Additionally, disclosed is a method for forming dopaminergic neurons by contacting neuroprogenitor cells to an effective amount of FGF-8 and Shh. Further described are compositions, cell culture compositions and medical devices which contain sufficient amount of FGF-8, Shh or FGF-8, Shh and FGF-4 to stimulate differentiation into dopaminergic or serotonergic neurons, respectively.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: August 21, 2001
    Assignee: Genentech, Inc.
    Inventors: Arnon Rosenthal, Mary A. Hynes, Weilan Ye