Abstract: A piston discharge structure for a plasma cloud excitation engine is provided. The piston discharge structure includes a movement electrode, a distributed multi-cavity combustion chamber, a fixed electrode, and a variable interval discharge region. The movement electrode is provided at a top portion of a piston and includes a first combination shape and a first movement electrode structure, the distributed multi-cavity combustion chamber is provided at the top portion of the piston, the fixed electrode is provided at a top portion of a cylinder block or a bottom portion of a cylinder head and including a second combination shape and a second structure, and the variable interval discharge region is defined by the movement electrode and the fixed electrode.

Abstract: The present disclosure provides a preparation method of an artificial antibody. The preparation method includes the following steps: screening a target siRNA from a conserved gene or a microsatellite of a coronavirus, synthesizing a small hairpin RNA (shRNA) that has a loop by complementary sense and antisense strands of the siRNA, synthesizing an ACE2 capable of binding to a receptor-binding domain (RBD), and synthesizing the artificial antibody including an shRNA region and an ACE2 region by ligating the ACE2 to sense and antisense strands of the shRNA separately. The bivalent ACE2 is used for neutralization of the RBD and targeted delivery of the shRNA; the shRNA is ligated to the virus through the ACE2 and enters target cells with virus infection, thereby avoiding a side effect of non-specific delivery of the shRNA to uninfected cells, as well as resisting the variant strain and neutralizing the virus with the ACE2.

Abstract: When it comes to monitoring human health, today's consumers are limited to so called “health trackers,” which count steps and calculate calorie burns. Traditional health trackers are only capable of measuring heart rate and are limited to external measurements. These devices are not capable of obtaining the internal body data and do not have access to human fluids. The personal health shield personal cloud case cover (or “health PCCC”) can not only analyze human fluids but also fluids being consumed by the user (food and drinks). The data collected from the fluids is then compared to a cloud or local data base. The results are displayed on a phone, tablet, personal computers, television, or any other device either mounted in the PCCC or connected to the health PCCC.

Abstract: Disclosed herein is a controlled drug release system of photoresponsive nanocarriers. Also provided are methods of making the nanocarriers. Also provided are method of using the nanocarriers for the treatment of diseases.

Abstract: Compositions and methods for selective mTOR inhibition and/or increase of autophagy in a tissue of a subject have been developed for the treatment of cancer. Caged mTOR inhibitor prodrugs including photo-cleavable protecting groups are provided for selective chemotherapy through an optochemical treatment system. Pharmaceutical compositions of mTOR inhibitors that are deactivated (caged) with a photo-removable protecting group to controllably block the inhibitory activity of the inhibitor are provided. The photo-removable group is cleavable upon exposure to light irradiation, releasing the active inhibitor of mTOR signaling and autophagy at the site of irradiation. An exemplary caged mTOR inhibitor prodrug is a caged OSI-027 prodrug having a DEACM moiety bound thereto (cOSI-027). The cOSI-027 is activated in the region of a tumor by removal of the DEACM protecting group by exposure to light at 420 nm.

Abstract: A radio frequency (RF) front end device has a signal traveling from a first antenna to a second antenna in an uplink path and a signal traveling from a third antenna to a fourth antenna in a downlink path. The device is under the control of automatic on/off controller (AOOC) which upon receiving a signal indication from a receive signal detector and amplifier (RSDA) turns on the operations of power amplifier (PA) and simultaneously turns off a low noise amplifier (LNA). This LNA is turned off when the power amplifier is turned on to prevent uplink path and downlink path forming a feedback loop which would result in oscillation, noise and interference.

Abstract: A Handy Base Station (HBS) which is capable of connecting through a base portion into a power socket (e.g., lamp socket). The HBS may have a plurality of functional modules capable of being detachably mounted in a housing. One of the functional modules may be a light emitter such as a light emitting diode (LED). Another module may be a a communication module which may communicate using a wire line or wirelessly using standard wireless communication protocols. Further disclosed is a combination unit which has the HBS located on a pole such as a utility pole with a landing pad for an unmanned aerial vehicle (UAV) to allow the UAV a recharging location between deliveries and to allow the HBS to guide the UAV on its flight.

Abstract: An antenna element comprises one or more directors, a resonator, and a three dimensional ground assembly. Parts of the antenna element are arranged on three metal layers. A top layer has an unconnected metal bar which forms a beam director, a resonator and a top part of the ground assembly. The resonator is an integral piece substantially in the form of a loop connected to a feed line and a feed line terminal ending. The feed line terminal ending serves as the ground plane for the feed line as well as providing impedance matching from the external transceiver circuit to the resonator. The ground assembly includes a top layer ground connected to a plurality of metallized half cylindrical hole channels (or metallized via holes) which connect to a ground terminal in a bottom layer.

Abstract: A system for monitoring a tank truck operation platform and for guiding and positioning vehicles and a method of using the same, the system includes operation platforms. Each of the operation platforms is provided with a lifting support. The operation platform is installed with an upper-position sensor, a lower-position sensor, and a stress sensor, which communicate with a central control device mounted on the operation platform. The central control device communicates with a distance meter and an in-place sensor for detecting the vehicle. The central control device may send signals to a display device, and information of platform status and vehicle position guidance are displayed on the display device to offer the driver with guidance information including whether the platform is safe and available, the moving direction of the vehicle, and position relative to the platform. Meanwhile, the central control device can receive identification information sent by the vehicle.

Abstract: A communication device comprising: a first unit having a first antenna, a second antenna, and a first signal transmitting and receiving circuitry; a second unit having a third antenna, a fourth antenna, and a second signal transmitting and receiving circuitry, wherein the second unit is located in proximity to the first unit; and wherein the second unit is capable of receiving signals at a first signal frequency, down converting the signals to a second signal frequency, and relaying the signals through a barrier to the first unit. Wherein the first signal frequency is in the millimeter wave range and the second signal frequency is in the microwave range.

Abstract: A piston discharge structure for a plasma cloud excitation engine is provided. The piston discharge structure includes a movement electrode, a distributed multi-cavity combustion chamber, a fixed electrode, and a variable interval discharge region. The movement electrode is provided at a top portion of a piston and includes a first combination shape and a first movement electrode structure, the distributed multi-cavity combustion chamber is provided at the top portion of the piston, the fixed electrode is provided at a top portion of a cylinder block or a bottom portion of a cylinder head and including a second combination shape and a second structure, and the variable interval discharge region is defined by the movement electrode and the fixed electrode.

Abstract: The present disclosure relates generally to instantaneous communication network systems and methods and, in particular, in one or more embodiments, the present disclosure relates to a first multi-mode and multi-frequency communication device capable of connecting directly with a proximate second first multi-mode and multi-frequency communication device. A display screen on the communication device is capable of displaying icons and avatars over a map to show other communication devices which are proximate.

Abstract: This disclosure provides methods of treating cancer with an inhibitor of ubiquitin specific peptidase 9X alone or in combination with an immune checkpoint pathway inhibitor.

Abstract: The field of various phototriggered drug release and photoreactions, including reactions generally based on triplet-triplet energy transfer with light excitation at long wavelengths. Systems and methods for absorbing energy in a photosensitizer, and methods for making or using such systems, kits including such systems. The systems and methods comprise transferring that energy by triplet-triplet energy transfer to cleave a cleavable or other active moiety, for instance, in order to cause the release of a releasable moiety. In some cases, these may be contained within a suitable carrier material, for example, a particle or a micelle. Such systems and methods may be used in a variety of applications, including various biological or physical applications. For example, such systems and methods may be useful for delivering drugs or other releasable moieties to regions of a subject.

Abstract: An antenna array for millimeter wave communications with a cell tower having a base station which allow for penetration of signals within a vehicle, building, glass or the like. In alternative embodiments, it may be a plurality of antenna arrays in communication with a base station (or cell tower) to provide 360 degrees of reception.

Abstract: The present invention relates to a rice seedling substrate and a preparation method thereof, which is of the technical field of rice planting. The rice seedling substrate according to the invention was prepared from the raw materials includes the following by volume: 40-60% of dredging sediment, 30-50% of vegetable straw, and 10-30% of hickory shell. The rice seedling substrate according to the invention can not only turn waste into treasure to improve the recycling rate of sediment and agricultural and forestry waste resources, but also save the limited cultivated soils, reduce the production cost of rice seedling substrate, and promote the healthy and sustainable development of rice planting. Therefore, The inventive substrate has significant benefits in terms of economics, sociology and ecology.

Abstract: A detection device and detection method for fusion of tactile sensing and optical tomography, including a handheld probe, a controller for performing signal control and data acquisition on the handheld probe and communicating with a computer, and the computer for performing data analysis and image reconstruction and display on controller information. The handheld probe includes a probe front cover. A tactile sensor, a probe base, and a photoelectric sensor module disposed in sequence are sandwiched between a first probe side cover and a second probe side cover matching the probe front cover. An optical fiber connected to the photoelectric sensor module is interposed between the first probe side cover and the second probe side cover. A detection method based on the detection device comprises detecting tumors inside biological tissue, and detecting physical changes (i.e. local hardness) of the tissue and functional changes (i.e. blood supply distribution) of the tissue.

Abstract: A mobile robot includes a body, a driving system connected to the body and configured to drive the mobile robot move on ground, a detecting module supported by the body and a controller received in the body. The detecting module includes a light source emitting light towards the ground, and a light sensor configured to obtain characteristic information and a shutter value of an image of the ground. The controller is configured to adjust the intensity of the light source according to the characteristic information of the image and monitor conditions of the ground according to the shutter value, which can accurately detect conditions of the ground and prevent misjudgment of the mobile robot.